Results 51 to 60 of about 44,822 (222)

Using phage Lytic Enzymes to Control Pathogenic Bacteria [PDF]

BMC Oral Health, 2006
Our laboratory has developed phage lytic enzymes to prevent infection by specifically destroying disease bacteria on mucous membranes and in blood. Enzymes specific for S. pneumoniae and S. pyogenes have been developed to be used nasally and orally to control these organisms in environments such as hospitals and nursing homes to prevent or markedly ...
openaire   +3 more sources

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Characterization of Three Phages Lytic for Brucella Species

Journal of General Virology, 1973
Summary The brucella phages A422, M51 and S708 were examined and compared with the Tbilisi reference phage. A422 was found to be identical in host range, adsorption pattern, physical and chemical stability and serological specificity with Tbilisi phage.
J A, Morris, M J, Corbel, J I, Phillip
openaire   +2 more sources

Programmable Klebsiella pneumoniae Phage Tropism Enabled by Scalable Receptor‐Binding Protein Mining and Modular Assembly

Advanced Science, EarlyView.
This work introduces a scalable, data‐driven strategy that turns the vast sequence diversity of phage receptor‐binding proteins into modular tools for engineering customizable phages. By clustering and experimentally validating diverse RBPs, the authors build an accurate map linking sequence to host specificity and create plug‐and‐play modules that ...
Shisong Jing, Yiyao Song, Xianbiao Bi, Yuqin Song, Dawei Wei, Jiangqing Huang, Yuan Zeng, Gang Zhang, Rong Zhang, Chao Wang, Jie Feng   +10 more
wiley   +1 more source

Toward Understanding Phage:Host Interactions in the Rumen; Complete Genome Sequences of Lytic Phages Infecting Rumen Bacteria

Frontiers in Microbiology, 2017
The rumen is known to harbor dense populations of bacteriophages (phages) predicted to be capable of infecting a diverse range of rumen bacteria. While bacterial genome sequencing projects are revealing the presence of phages which can integrate their ...
Rosalind A. Gilbert, Rosalind A. Gilbert, William J. Kelly, Eric Altermann, Eric Altermann, Sinead C. Leahy, Sinead C. Leahy, Catherine Minchin, Diane Ouwerkerk, Diane Ouwerkerk, Athol V. Klieve, Athol V. Klieve   +11 more
doaj   +1 more source

Characterization of a lytic Pseudomonas aeruginosa phage vB_PaeP_ASP23 and functional analysis of its lysin LysASP and holin HolASP

Frontiers in Microbiology, 2023
In this study, we isolated a lytic Pseudomonas aeruginosa phage (vB_PaeP_ASP23) from the sewage of a mink farm, characterized its complete genome and analyzed the function of its putative lysin and holin.
Jiaqi Cui, Xiaojie Shi, Xinwei Wang, Huzhi Sun, Yanxin Yan, Feiyang Zhao, Can Zhang, Wenhua Liu, Ling Zou, Lei Han, Qiang Pan, Huiying Ren   +11 more
doaj   +1 more source

Comparative susceptibility of mosquito populations in North Queensland, Australia to oral infection with dengue virus. [PDF]

, 2014
Dengue is the most prevalent arthropod-borne virus, with at least 40% of the world's population at risk of infection each year. In Australia, dengue is not endemic, but viremic travelers trigger outbreaks involving hundreds of cases.
Anderson, Andrew F. van den Hurk, Armstrong, Armstrong, Beebe, Beebe, Bennett, Bosio, Chevillon, Elizabeth A. McGraw, Endersby, Failloux, Forrester, Francesca D. Frentiu, Frentiu, Gubler, Gubler, Gubler, Guzman, Halstead, Halstead, Hanna, Holmes, Holmes, Huber, Kien, Knox, Kyle, Lambrechts, Lambrechts, Moreira, Neff, Nigel W. Beebe, Parameswaran, Paupy, Rosen, Ross, Scott L. O'Neill, Tat Siong Ng, Thomas Walker, Van Den Hurk, Vasilakis, Vazeille-Falcoz, Warrilow, Xi, Ye, Yixin H. Ye, Yoon   +47 more
core   +2 more sources

Alternating High‐Fat and Polysaccharide Diets Modulates Gut Phage‐Bacterial Interplay

Advanced Science, EarlyView.
This study reveals how alternating high‐fat and polysaccharide diets reshape the human gut virome and enhance phage‐bacteria interactions. Using large‐scale metagenomic meta‐analysis and a time‐resolved mouse model, the authors show that diets strongly modulate phage abundance, lifestyle, and gene exchange, offering new insights into nutrition‐guided ...
Fengxiang Zhao, Ruiqi Zhang, Rujun Wei, Huimin Fan, Yongfei Hu, Wenyu Shi, Jinfeng Wang   +6 more
wiley   +1 more source

The Novel Enterococcus Phage vB_EfaS_HEf13 Has Broad Lytic Activity Against Clinical Isolates of Enterococcus faecalis

Frontiers in Microbiology, 2019
Enterococcus faecalis is a Gram-positive, facultative anaerobic bacterium frequently found in the gastrointestinal tract, oral cavity, and periodontal tissue.
Dongwook Lee, Jintaek Im, Hongjun Na, Sangryeol Ryu, Cheol-Heui Yun, Seung Hyun Han   +5 more
doaj   +1 more source

Force for ancient and recent life: viral and stem-loop RNA consortia promote life. [PDF]

, 2014
Lytic viruses were thought to kill the most numerous host (i.e., kill the winner). But persisting viruses/defectives can also protect against viruses, especially in a ubiquitous virosphere. In 1991, Yarmolinsky et al.
Villarreal, Luis P
core   +1 more source