Results 11 to 20 of about 497,028 (181)

Müller Glia to Müller Glia Extracellular Vesicle-Dependent Signaling Induces Multipotency Genes and l Expression in Response to N-methyl-D-aspartate (NMDA) Exposure

open access: yesASN Neuro, 2023
A strict localization into the neural retina and the capacity to survive many pathogenic conditions are unique characteristics of Müller glia. Retinal damage induces cellular and molecular changes that place Müller cells as focal points to either protect
Ana Karen Carapia   +6 more
doaj   +2 more sources

Analysis of Müller glia specific genes and their histone modification using Hes1-promoter driven EGFP expressing mouse

open access: yesScientific Reports, 2017
Retinal neurons and Müller glia are generated from a common population of multipotent retinal progenitor cells. We purposed to identify Müller glia-specific molecular signatures during retinal development. Using transgenic mice carrying the Hes1 promoter
Kazuko Ueno   +7 more
doaj   +2 more sources

Investigating Müller glia reprogramming in mice: a retrospective of the last decade, and a look to the future

open access: yesNeural Regeneration Research
Müller glia, as prominent glial cells within the retina, plays a significant role in maintaining retinal homeostasis in both healthy and diseased states.
Zhiyuan Yin   +5 more
doaj   +2 more sources

A Müller Glia-Retinal Pigment Epithelium Apical Network Surrounding Cone Outer Segments in Fish and Mouse. [PDF]

open access: yesGlia
Müller glia and the retinal pigment epithelium interact around cone outer segment in the subretinal space of both zebrafish and mouse. The contacts are established early during development but subsequent to outer segment emergence. ABSTRACT Homeostasis of the vertebrate retina critically depends on two non‐neuronal cell populations, Müller glia and the
Sharkova M   +6 more
europepmc   +2 more sources

In vivo and ex vivo evaluation of the responses of rat Müller glia after injury [PDF]

open access: yesScientific Reports
Retinal ex vivo systems have been widely used to investigate diverse physiological and pathological processes in the retina. Although retinal ex vivo systems are generally considered to approximate in vivo environment of the retina, careful evaluation of
Kaori Nomura-Komoike   +3 more
doaj   +2 more sources

Müller Glia Subtypes Define Neuro-Glial Associations and Spatial Morphogen Axes in the Zebrafish Retina. [PDF]

open access: yesGlia
Zebrafish Müller glia are heterogeneous in the early larval retina. Zebrafish Müller glia subtypes define a spatial axis of retinoic acid metabolism. Neuron‐associated glial programs identified in Zebrafish Müller glia are evolutionarily conserved in mammals. ABSTRACT Müller glia are instrumental macroglia of the vertebrate retina, once thought to be a
Storey SS   +3 more
europepmc   +2 more sources

Unusual morphology of foveal Müller glia in an adult human born pre-term [PDF]

open access: yesFrontiers in Cellular Neuroscience
The fovea of the human retina, a specialization for acute and color vision, features a high concentration of cone photoreceptors. A pit on the inner retinal aspect is created by the centrifugal migration of post-receptoral neurons.
Deepayan Kar   +9 more
doaj   +2 more sources

Yap Regulates Müller Glia Reprogramming in Damaged Zebrafish Retinas [PDF]

open access: yesFrontiers in Cell and Developmental Biology, 2021
Vertebrates such as zebrafish have the outstanding ability to fully regenerate their retina upon injury, while mammals, including humans, do not. In zebrafish, upon light-induced injury, photoreceptor regeneration is achieved through reprogramming of ...
Raquel Lourenço   +4 more
doaj   +2 more sources

Translatomic response of retinal Müller glia to acute and chronic stress

open access: yesNeurobiology of Disease, 2022
Analysis of retina cell type-specific epigenetic and transcriptomic signatures is crucial to understanding the pathophysiology of retinal degenerations such as age-related macular degeneration (AMD) and delineating cell autonomous and cell-non-autonomous
Ana J. Chucair-Elliott   +8 more
doaj   +2 more sources

Cellular Signaling in Müller Glia: Progenitor Cells for Regenerative and Neuroprotective Responses in Pharmacological Models of Retinal Degeneration

open access: yesJournal of Ophthalmology, 2019
Retinal degenerative diseases are a leading cause of visual impairment or blindness. There are many therapies for delaying the progression of vision loss but no curative strategies currently.
Yang Liu, Chenguang Wang, Guanfang Su
doaj   +2 more sources

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