Results 31 to 40 of about 30,858,840 (226)

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

Membranous nephropathy [PDF]

open access: yesBrazilian Journal of Nephrology, 2023
Membranous nephropathy is a glomerulopathy, which main affected target is the podocyte, and has consequences on the glomerular basement membrane. It is more common in adults, especially over 50 years of age.
Márcio Dantas   +5 more
doaj   +1 more source

sj-pdf-1-cjk-10.1177_20543581211052729 – Supplemental material for Qualitative and Quantitative Dosage of the Anti M-Type Phospholipase A2 Receptor Autoantibody: One-Year Experience in Quebec’s Reference Center

open access: yes, 2021
Supplemental material, sj-pdf-1-cjk-10.1177_20543581211052729 for Qualitative and Quantitative Dosage of the Anti M-Type Phospholipase A2 Receptor Autoantibody: One-Year Experience in Quebec’s Reference Center by Simon Leclerc, Karim Benkirane, Annie ...
Simon Leclerc (1862623)   +8 more
core   +1 more source

Enhanced expression of the M-type phospholipase A2 receptor in glomeruli correlates with serum receptor antibodies in primary membranous nephropathy [PDF]

open access: yesKidney International, 2012
The M-type phospholipase A2 receptor (PLA2R) is the major target antigen in idiopathic membranous nephropathy with detectable autoantibodies in the serum of up to 70% of patients. In retrospective studies, the PLA2R-autoantibody titer in the serum was sometimes negative indicating their measurement alone may be inconclusive.
Hoxha, Elion   +8 more
openaire   +2 more sources

Diagnostic Test Accuracy of Serum Anti-PLA2R Autoantibodies and Glomerular PLA2R Antigen for Diagnosing Idiopathic Membranous Nephropathy: An Updated Meta-Analysis

open access: yesFrontiers in Medicine, 2018
BackgroundM-type phospholipase A2 receptor (PLA2R) is known as a major antigen on podocytes, which is involved with the pathogenesis of idiopathic membranous nephropathy (iMN).
Weiying Li, Yuliang Zhao, Ping Fu
doaj   +1 more source

Critical evaluation of cancer risks in glomerular disease

open access: yesTranslational Oncology, 2022
The increased cancer incidence in patients with glomerular disease can be secondary to an intrinsic immune dysfunction associated with the disease or/and extrinsic factors, especially immunosuppressants. The treatment for paraneoplastic glomerulopathy is
Zaw Thet   +5 more
doaj   +1 more source

Clinical significance of antibodies to the M-type phospholipase A2 receptor in patients with primary membranous nephropathy

open access: yesClinical pharmacology and therapy, 2023
To evaluate the significance of circulating antibodies to the M-type phospholipase A2 receptor (anti-PLA2R) in the diagnosis of primary membranous nephropathy (MN) and the determination of the clinical features of the disease.
O.A. Li   +4 more
openaire   +1 more source

Relationship between membrane phosphatidylinositol-4,5-bisphosphate and receptor-mediated inhibition of native neuronal M channels [PDF]

open access: yes, 2005
The relationship between receptor-induced membrane phosphatidylinositol-4'5'-bisphosphate (PIP2) hydrolysis and M-current inhibition was assessed in single-dissociated rat sympathetic neurons by simultaneous or parallel recording of membrane current and ...
Abogadie, FC   +6 more
core   +2 more sources

Efficacy and Safety of Different Immunosuppressive Therapies in Patients With Membranous Nephropathy and High PLA2R Antibody Titer

open access: yesFrontiers in Pharmacology, 2022
Background: This study aimed to evaluate clinical features and prognosis and therapy option of patients with different risk ranks based on antibody against the M-type phospholipase-A2-receptor (PLA2Rab) level in seropositive M-type phospholipase-A2 ...
Le Deng   +7 more
doaj   +1 more source

Serum anti-phospholipase A2 receptor (PLA2R) antibody detected at diagnosis as a predictor for clinical remission in patients with primary membranous nephropathy: a meta-analysis

open access: yesBMC Nephrology, 2019
Background The diagnostic value of serum M-type phospholipase A2 receptor antibody (sPLA2R-ab) expression in patients with primary membranous nephropathy (PMN) has been established.
Yufeng Liang   +3 more
doaj   +1 more source

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