Results 21 to 30 of about 4,686 (145)

Genetic variants of m1A modification genes and the risk of neuroblastoma: novel insights from a Chinese case-control study [PDF]

Human Genomics
Background The N1-adenosine methylation (m1A) modification plays a significant role in various cancers. However, the functions of m1A modification genes and their variants in neuroblastoma remain to be elucidated.
Jiaming Chang, Lei Lin, Wenli Zhang, Jiliang Yang, Mengzhen Zhang, Huimin Yin, Xinxin Zhang, Chunlei Zhou, Yan Zou, Jing He   +9 more
doaj   +2 more sources

Identification and validation of an m1A-score model to predict outcomes and immunomodulation in lung squamous cell carcinoma by integrated analysis of single-cell and bulk RNA sequencing [PDF]

Discover Oncology
Lung squamous cell carcinoma (LUSC) is a common and aggressive subtype of lung cancer, characterized by difficult treatment and poor prognosis. N1-methyladenosine (m1A) is an RNA modification that plays a crucial role in various biological processes ...
Han Gong, Haihang Zhang, Lin Zhu, Jing Liu, Dehui Xiong, Yibin Zhang   +5 more
doaj   +2 more sources

The m1A modification of tRNAs: a translational accelerator of T-cell activation. [PDF]

Cell Mol Immunol, 2022
Chen C, Ye L.
europepmc   +3 more sources

tRNA-m¹A modification: a translational checkpoint for T cell expansion. [PDF]

Cell Res, 2023
Pei W, Kuchroo VK.
europepmc   +3 more sources

Comprehensive analyses of m1A regulator-mediated modification patterns determining prognosis in lower-grade glioma (running title: m1A in LGG)

Heliyon
N1-methyladenosine (m1A) modification is a crucial post-transcriptional regulatory mechanism of messenger RNA (mRNA) in living organisms. Few studies have focused on analysis of m1A regulators in lower-grade gliomas (LGG).
Kunjian Lei, Yilei Sheng, Min Luo, Junzhe Liu, Chuandong Gong, Shigang Lv, Wei Tu, Minhua Ye, Miaojing Wu, Bing xiao, Hua Fang, Haitao Luo, Xinjun Liu, Xiaoyan Long, Xingen Zhu, Kai Huang, Jingying Li   +16 more
doaj   +3 more sources

Methyladenine as a regulator of biomolecular condensation [PDF]

Frontiers in Molecular Biosciences
Ribonucleotide modifications modulate RNA structure and stability, thereby influencing RNA turnover and a wide range of cellular functions. Recent studies have revealed that specific RNA modifications can also affect the formation, composition, and ...
Roberto Arsiè, Gian G. Tartaglia, R. Martin Vabulas   +2 more
doaj   +2 more sources

Correction: The landscape of m1A modification and its posttranscriptional regulatory functions in primary neurons.

Elife, 2023
Zhang C, Yi X, Hou M, Li Q, Li X, Lu L, Qi E, Wu M, Qi L, Jian H, Qi Z, Lv Y, Kong X, Bi M, Feng S, Zhou H.   +15 more
europepmc   +3 more sources

ALKBH3 suppresses ischemia/reperfusion‐induced PANoptosis by regulating the ZBED6/STAT1/AIM2 axis through m1A demethylation [PDF]

Clinical and Translational Medicine
Background Myocardial ischemia/reperfusion (I/R) injury induces an intense inflammatory response and involves multiple cell death pathways. PANoptosis, an integrated cell death process involving pyroptosis, apoptosis and necroptosis, is a major driver of
Hongtao Diao, Chunlei Wang, Yuting Xiong, Qiaoyue Zhao, Xinyue Zhang, Xiaohui Qi, Yuan Zou, Jiaxuan Li, Linghua Zeng, Wei Si, Feng Zhang, Ping Pang, Ning Wang, Yu Bian, Baofeng Yang   +14 more
doaj   +2 more sources

N1-methyladenosine modification in cancer biology: Current status and future perspectives

Computational and Structural Biotechnology Journal, 2022
Post-transcriptional modifications in RNAs regulate their biological behaviors and functions. N1-methyladenosine (m1A), which is dynamically regulated by writers, erasers and readers, has been found as a reversible modification in tRNA, mRNA, rRNA and ...
Jiexin Li, Haisheng Zhang, Hongsheng Wang   +2 more
doaj   +1 more source

Comprehensive of N1-Methyladenosine Modifications Patterns and Immunological Characteristics in Ovarian Cancer

Frontiers in Immunology, 2021
Backgroundrecently, many researches have concentrated on the relevance between N1-methyladenosine (m1A) methylation modifications and tumor progression and prognosis.
Jinhui Liu, Can Chen, Yichun Wang, Cheng Qian, Junting Wei, Yan Xing, Jianling Bai   +6 more
doaj   +1 more source