Results 31 to 40 of about 1,872,691 (138)

Correction: The landscape of m1A modification and its posttranscriptional regulatory functions in primary neurons

eLife, 2023
Chi Zhang, Xianfu Yi, Mengfan Hou, Qingyang Li, Xueying Li, Lu Lu, Enling Qi, Mingxin Wu, Lin Qi, Huan Jian, Zhangyang Qi, Yigang Lv, Xiaohong Kong, Mingjun Bi, Shiqing Feng, Hengxing Zhou   +15 more
semanticscholar   +3 more sources

Identification of the m6A/m5C/m1A methylation modification genes in Alzheimer’s disease based on bioinformatic analysis

Aging
Background: As a progressive neurodegenerative disease, the comprehensive understanding of the pathogenesis of Alzheimer’s disease (AD) is yet to be clarified. Modifications in RNA, including m6A/m5C/m1A, affect the onset and progression of many diseases.
Qifa Tan, Desheng Zhou, Yuan Guo, Haijun Chen, Peng Xie   +4 more
semanticscholar   +3 more sources

Clinician’s Guide to Epitranscriptomics: An Example of N1-Methyladenosine (m1A) RNA Modification and Cancer

Life
Epitranscriptomics is the study of modifications of RNA molecules by small molecular residues, such as the methyl (-CH3) group. These modifications are inheritable and reversible.
Ana Kvolik Pavić, Josipa Čonkaš, Ivan Mumlek, Vedran Zubčić, Petar Ozretić   +4 more
semanticscholar   +2 more sources

tRNA-m1A Modification Safeguards Fetal Liver HSPCs from DNA Damage via Maintaining Iron Homeostasis.

Blood Journal
Hematopoietic stem and progenitor cell (HSPC) development requires finely tuned gene expression programs, yet the role of tRNA modifications in this process remains largely unknown.
Yining Liu, Yichen Ma, Panfeng Li, Yong-Jiang li, Guixian Liang, Xiaoting Zhang, Baofeng Huang, Jinying Peng, Dongyuan Ma, Lu Wang, Ang Li, Chengqi Yi, Feng Liu   +12 more
semanticscholar   +2 more sources

Blood N1-methyladenosine (m1A) RNA modification and outcome after cardiac arrest [PDF]

Critical Care
Background Cardiac arrest (CA) is a leading cause of mortality and neurological disability. Prediction of post-CA outcomes is challenging. Epitranscriptomic (RNA) modifications are emerging as potential biomarkers due to their regulatory roles in RNA ...
V. Stopa, M. Sopić, François Bernardin, N. Legrave, Lu Zhang, P. Stammet, Yvan Devaux   +6 more
semanticscholar   +5 more sources

N1-methyladenosine modification in cancer biology: Current status and future perspectives

Computational and Structural Biotechnology Journal, 2022
Post-transcriptional modifications in RNAs regulate their biological behaviors and functions. N1-methyladenosine (m1A), which is dynamically regulated by writers, erasers and readers, has been found as a reversible modification in tRNA, mRNA, rRNA and ...
Jiexin Li, Haisheng Zhang, Hongsheng Wang   +2 more
doaj   +1 more source

Comprehensive of N1-Methyladenosine Modifications Patterns and Immunological Characteristics in Ovarian Cancer

Frontiers in Immunology, 2021
Backgroundrecently, many researches have concentrated on the relevance between N1-methyladenosine (m1A) methylation modifications and tumor progression and prognosis.
Jinhui Liu, Can Chen, Yichun Wang, Cheng Qian, Junting Wei, Yan Xing, Jianling Bai   +6 more
doaj   +1 more source

TRMT10C promotes mitochondrial fission through transferrin receptor m1A methylation modification and aggravates the progression of atrial fibrillation

Journal of Cell Communication and Signaling
Atrial fibrillation (AF) is a common cardiac arrhythmia often accompanied by structural remodeling of the atria, particularly fibrosis, and disruption of normal mitochondrial function.
Nijina Li, Hao Zhang
semanticscholar   +2 more sources

N1-Methyladenosine modification of mRNA regulates neuronal gene expression and oxygen glucose deprivation/reoxygenation induction

Cell Death Discovery, 2023
N1-Methyladenosine (m1A) is an abundant modification of transcripts, plays important roles in regulating mRNA structure and translation efficiency, and is dynamically regulated under stress.
Zhangyang Qi, Chi Zhang, Huan Jian, Mengfan Hou, Yongfu Lou, Yi Kang, Wei Wang, Yigang Lv, Shenghui Shang, Chaoyu Wang, Xueying Li, Shiqing Feng, Hengxing Zhou   +12 more
doaj   +1 more source

Comprehensive Analysis of the Function, Immune Profiles, and Clinical Implication of m1A Regulators in Lung Adenocarcinoma

Frontiers in Oncology, 2022
BackgroundPrevious studies have demonstrated that transcriptional RNA methyladenosine modification significantly affects tumor initiation and progression.
Guangyao Bao, Tian Li, Xiaojiao Guan, Yao Yao, Jie Liang, Yifang Xiang, Xinwen Zhong   +6 more
doaj   +1 more source