Results 81 to 90 of about 8,365 (191)

m1A regulator-mediated methylation modification patterns correlated with autophagy to predict the prognosis of hepatocellular carcinoma

BMC Cancer
Background N1-methyladenosine (m1A), among the most common internal modifications on RNAs, has a crucial role to play in cancer development. The purpose of this study were systematically investigate the modification characteristics of m1A in ...
Yingmin Wu, Lian Li, Long Wang, Shenjie Zhang, Zhirui zeng, Jieyu Lu, Zhi Wang, Yewei Zhang, Shilong Zhang, Haiyang Li, Tengxiang Chen   +10 more
doaj   +1 more source

The Query-commit Problem [PDF]

, 2011
In the query-commit problem we are given a graph where edges have distinct probabilities of existing. It is possible to query the edges of the graph, and if the queried edge exists then its endpoints are irrevocably matched.
Molinaro, Marco, Ravi, R.
core  

Quons Restricted to the Antisymmetric Subspace: Formalism and Applications [PDF]

, 2002
In this work we develop a formalism to treat quons restricted to the antisymmetric part of their many-body space. A model in which a system of identical quons interact through a pairing force is then solved within this restriction and the differences ...
Amusia, Avancini, Avancini, Avancini, Avancini, Avancini, Cambiaggio, Cambiaggio, Chaichian, D.P. Menezes, Dukelsky, Edmonds, F.F. de Souza Cruz, Greenberg, Heiselberg, J.R. Marinelli, Keldysh, Lipkin, M.M. Watanabe de Moraes, Mysyrowics, Richardson, Richardson, Richardson, Ring, S.S. Avancini, Sierra, Wolfe   +26 more
core   +2 more sources

Establishment of a new molecular subtyping and prognostic signature with m6A/m5C/m1A/m7G regulatory genes for hepatocellular carcinoma

Heliyon, 2023
Background: RNA modification, including m6A, m5C, m1A, and m7G, participated in tumor progress. Therefore, the purpose of the present study was to explore the role of m6A/m5C/m1A/m7G regulatory genes in the prognosis and tumor microenvironment (TME) for ...
Ting Liu, Yang Wang, Zhizhao Li, Lei Sun, Kun Yang, Jiamin Chen, Xiaoyi Han, Liming Qi, Xingang Zhou, Peng Wang   +9 more
doaj   +1 more source

Estimating empirical codon hidden Markov models [PDF]

, 2017
Empirical codon models (ECMs) estimated from a large number of globular protein families outperformed mechanistic codon models in their description of the general process of protein evolution.
De Maio, Nicola, Holmes, Ian, Kosiol, Carolin, Schlötterer, Christian   +3 more
core   +1 more source

Ribozymes for RNA‐Catalyzed RNA Methylation and Labeling

Angewandte Chemie International Edition, EarlyView.
Ribozymes are powerful tools for site‐specific RNA modification. Their activities range from installing tags and fluorophores to generating natural RNA methylations, making them valuable tools to uncover the many functions that RNA plays in nature.
Carolin P. M. Scheitl, Claudia Höbartner   +1 more
wiley   +1 more source

m1A inhibition fuels oncolytic virus-elicited antitumor immunity via downregulating MYC/PD-L1 signaling

International Journal of Oral Science
N 1-methyladenosine (m1A) RNA methylation is critical for regulating mRNA translation; however, its role in the development, progression, and immunotherapy response of head and neck squamous cell carcinoma (HNSCC) remains largely unknown.
Shujin Li, Tian Feng, Yuantong Liu, Qichao Yang, An Song, Shuo Wang, Jun Xie, Junjie Zhang, Bifeng Yuan, Zhijun Sun   +9 more
doaj   +1 more source

Similarity Structure Analysis and Structural Equation Modeling in Studying Latent Structures: An Application to the Attitudes towards Portuguese Language Questionnaire [PDF]

, 2017
Several international studies such as PISA and PILRS (Progress in International Reading Literacy Study), have stressed the importance of positive attitudes and behaviours as facilitators of individuals reading literacy during the school years and ...
Candeias, A.A., Diniz, A., Roazzi, A.
core  

Genome-wide evidence for positive selection and recombination in Actinobacillus pleuropneumoniae [PDF]

, 2011
Background Actinobacillus pleuropneumoniae is an economically important animal pathogen that causes contagious pleuropneumonia in pigs. Currently, the molecular evolutionary trajectories for this pathogenic bacterium remain to require a better ...
Zhuofei Xu, Huanchun Chen, Rui Zhou
core   +1 more source

The Naturally Occurring m1A RNA Modification Can Be Efficiently Incorporated into RNA by SARS-CoV-2 RdRp

, 2023
Abstract When it is in the template RNA, the naturally occurring m1A epitranscriptomic RNA modification was recently reported to be able to stop the RNA polymerization reaction catalyzed by the RNA dependent RNA polymerase (RdRp) of SARS-CoV-2. In this report, we report that m1A via its triphosphate form (m1ATP) can be incorporated into RNA by ...
Alexander Apostle, Reed Arneson, Yinan Yuan, Shiyue Fang   +3 more
openaire   +1 more source