Results 61 to 70 of about 4,686 (145)

Additional file 1 of m1A methylation modification patterns and metabolic characteristics in hepatocellular carcinoma

open access: yes, 2022
Additional file 1: Table S1. Clinical Characteristics of the HCC patients in TCGA and ICGC; Figure S1. Expression levels of m1A regulators in HCC and normal tissues; Figure S2. Unsupervised clustering of m1A regulators and metabolic characteristics in each cluster; Figure S3.
Tong, Chengcheng, Wang, Wei, He, Chiyi
openaire   +1 more source

Establishment of a new molecular subtyping and prognostic signature with m6A/m5C/m1A/m7G regulatory genes for hepatocellular carcinoma

open access: yesHeliyon, 2023
Background: RNA modification, including m6A, m5C, m1A, and m7G, participated in tumor progress. Therefore, the purpose of the present study was to explore the role of m6A/m5C/m1A/m7G regulatory genes in the prognosis and tumor microenvironment (TME) for ...
Ting Liu   +9 more
doaj   +1 more source

Parallel Liquid Biopsy Analysis of miR‐371a‐3p and Cell‐Free DNA in an Unselected Cohort of Patients With Testicular Germ Cell Tumors

open access: yesAndrology, EarlyView.
ABSTRACT Background Despite robust data showing strong potential to improve diagnosis and disease monitoring in testicular germ cell tumors (TGCTs), miR‐371a‐3p testing has not yet been implemented in routine clinical practice. Cell‐free DNA (cfDNA) represents another promising liquid biopsy biomarker that may provide complementary molecular ...
Laura Matouskova   +6 more
wiley   +1 more source

m1A inhibition fuels oncolytic virus-elicited antitumor immunity via downregulating MYC/PD-L1 signaling

open access: yesInternational Journal of Oral Science
N 1-methyladenosine (m1A) RNA methylation is critical for regulating mRNA translation; however, its role in the development, progression, and immunotherapy response of head and neck squamous cell carcinoma (HNSCC) remains largely unknown.
Shujin Li   +9 more
doaj   +1 more source

Neuroimaging and neurophysiology in infantile‐onset epilepsy after neonatal stroke

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
This population‐based retrospective cohort study of 55 newborn infants demonstrated that neonatal MRI and neonatal neurophysiology (amplitude‐integrated EEG, conventional EEG, and somatosensory evoked potentials) combined with follow‐up EEGs during the first year of life provide practical tools for identifying infants at the highest risk of developing ...
Sinikka La Grassa   +6 more
wiley   +1 more source

The Naturally Occurring m1A RNA Modification Can Be Efficiently Incorporated into RNA by SARS-CoV-2 RdRp

open access: yes, 2023
Abstract When it is in the template RNA, the naturally occurring m1A epitranscriptomic RNA modification was recently reported to be able to stop the RNA polymerization reaction catalyzed by the RNA dependent RNA polymerase (RdRp) of SARS-CoV-2. In this report, we report that m1A via its triphosphate form (m1ATP) can be incorporated into RNA by ...
Alexander Apostle   +3 more
openaire   +1 more source

Japanese Women's Attitudes Toward Learning Languages Other Than English in the Era of Global English

open access: yesInternational Journal of Applied Linguistics, EarlyView.
ABSTRACT This study on female Japanese learners of the Korean language is situated in the centuries‐long anti‐Korean sentiments in Japan, the global popularity of the Korean Wave, particularly among women, and the essentialized image of socially marginalized young Japanese women who study English with romantic desires for Western men.
Yoko Kobayashi
wiley   +1 more source

Enrichment‐Based Duplex PCR for Early Detection of Potentially Virulent Vibrio harveyi in Aquaculture

open access: yesJournal of Fish Diseases, EarlyView.
ABSTRACT Vibrio harveyi is an important bacterial pathogen in marine aquaculture, responsible for outbreaks affecting a wide range of fish species. Early detection of potentially virulent isolates in fish and environmental samples is essential for effective disease prevention and management, particularly under field conditions where the pathogen may be
Javier Barriga‐Cuartero   +4 more
wiley   +1 more source

m1A demethylase Alkbh3 regulates neurogenesis through m1A demethylation of Mmp15 mRNA

open access: yesCell & Bioscience
Background N1-Methyladenosine (m1A) is an abundant modification of transcripts regulating mRNA structure and translation efficiency. However, the characteristics and biological functions of mRNA m1A modification in adult hippocampal neurogenesis remain ...
Huan Wang   +9 more
doaj   +1 more source

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