Results 71 to 80 of about 4,686 (145)

Harnessing Star Power: The Distinct Effects of Star Inventors on Radical and Incremental Innovation

Journal of Management Studies, EarlyView.
Abstract Star inventors are highly valuable resources, offering scarce knowledge and expertise that significantly enhance a firm's innovation performance. Beyond their expertise, what sets star inventors apart is their star status – a role that prescribes them high positions in organizational hierarchy and the power to steer resource allocation within ...
Murod Aliyev, Hyungseok David Yoon
wiley   +1 more source

Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis

Angewandte Chemie, Volume 138, Issue 25, 15 June 2026.
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley   +2 more sources

Periodontitis and Diabetes: Mechanistic Evidence of a Circular Relationship

Journal of Periodontal Research, EarlyView.
This narrative review aimed to explore the underlying mechanisms that connect periodontitis to diabetes (and vice versa) and that influence disease susceptibility, progression and response to treatment. ABSTRACT The circular relationship between periodontitis and diabetes mellitus is one of the most established oral‐systemic links.
Philip M. Preshaw, Ren Jie Jacob Chew, Charlene Enhui Goh, Ali A. Abdulkareem, Dana T. Graves   +4 more
wiley   +1 more source

Origin and formation of a chondritic xenolith in Krymka (LL3.2, breccia): Indications for a late formation of the accretionary breccia

Meteoritics &Planetary Science, EarlyView.
Abstract An unusual chondritic xenolith was found in two sequentially prepared thin sections of a sample from the Krymka (LL3.2) chondrite. The xenolith has a rounded, slightly deformed shape of about 5 mm in apparent diameter and is partially surrounded by a double rim made of an inner fine‐grained silicate‐rich rim and an outer sulfide‐rich rim.
Aelita Girich, Addi Bischoff, Samuel Ebert, Kazuhide Nagashima, Andreas Morlok, Harald Hiesinger, Jasper Berndt   +6 more
wiley   +1 more source

The Living Arrangements of Single Mothers in Latin America: Stratification by Education and Partnership Status

Population and Development Review, EarlyView.
Abstract One in four young mothers in Latin America raises her children without a partner, yet more than two‐thirds do so within extended households, typically with their own parents. Despite the social implications of single‐parent families, it remains unclear to what extent the prevalence and living arrangements of single mothers have evolved over ...
Federica Becca, Diego Alburez‐Gutierrez, Albert Esteve   +2 more
wiley   +1 more source

Clinical and Radiometabolic Correlatives of ddPCR Liquid Biopsy for BRAF V600 Mutated Melanoma

International Journal of Cancer, Volume 159, Issue 4, Page 1068-1078, 15 August 2026.
Commercial circulating tumor DNA (ctDNA) liquid biopsy tests are increasingly used for disease monitoring and surveillance in melanoma. However, data regarding the possible correlations between ctDNA and baseline clinical and radiometabolic parameters such as metastatic locations, tumor volume, and tumor glycolysis in patients with BRAF‐mutated ...
Ronen Stoff, Gokce Belge Bilgin, Yalda Nikanpour, Geoffrey B. Johnson, Benjamin R. Kipp, David M. Zahrieh, Katherine B. Geiersbach, Matthew S. Block, Svetomir N. Markovic   +8 more
wiley   +1 more source

Identification of the m6A/m5C/m1A methylation modification genes in Alzheimer’s disease based on bioinformatic analysis

Aging
As a progressive neurodegenerative disease, the comprehensive understanding of the pathogenesis of Alzheimer's disease (AD) is yet to be clarified. Modifications in RNA, including m6A/m5C/m1A, affect the onset and progression of many diseases. Consequently, this study focuses on the role of methylation modification in the pathogenesis of AD.Three AD ...
Tan, Qifa, Zhou, Desheng, Guo, Yuan, Chen, Haijun, Xie, Peng   +4 more
openaire   +2 more sources

Prediction of the individual risk for the development of brain metastases in patients with non‐oncogene‐addicted non‐small cell lung cancer: Real‐world data from the German prospective CRISP registry (AIO‐TRK‐0315)

International Journal of Cancer, Volume 159, Issue 3, Page 739-749, 1 August 2026.
What's New? Estimating the risk of developing brain metastases may enable earlier diagnosis and treatment, potentially reducing morbidity and mortality. Using the prospective CRISP lung cancer registry, the authors developed and validated a point‐based classifier for the risk of developing first brain metastases in patients with advanced or metastatic ...
Fabian Acker, Katharina Wenger, Martin Reck, Cornelius F. Waller, Petra Hoffknecht, Andre Bethge, Arnd Nusch, Marcel Reiser, Christiane Bernhardt, Michael Bendel, Carolin Lennartz, Annette Fleitz, Martina Jänicke, Paula Ludwig, Annika Groth, Frank Griesinger, Michael Thomas, Wilfried E. E. Eberhardt, Martin Sebastian, for the CRISP Registry Group, Juliana Ababei, Jürgen Alt, Andreas Ammon, Sven Philip Aries, Akin Atmaca, Ivo Azeh, Eva‐Maria Barkowsky, Stefan Bauer, Silvan Becker, Dirk Behringer, Michael Bendel, Robin Benkelmann, Veronika Berberich, André Bethge, Annalen Bleckmann, Michael Boesche, Sabine Bohnet, Harald‐Robert Bruch, Wolfgang Brückl, Ulrike Burkhard‐Meier, Dieter Bürkle, Daniel C. Christoph, Petros Christopoulos, Peter Czyborra, Klaus‐Ulrich Däßler, Maike de Wit, Tobias Dechow, Reinhard Depenbusch, Karl‐Matthias Deppermann, Nicolas Dickgreber, Lutz Dietze, Markus Dommach, Steffen Dörfel, Wilfried Eberhardt, Ekkehard Eigendorff, Corinna Elender, Wolfgang Elsel, Till‐Oliver Emde, Bastian Eul, Martin Faehling, Florian Fauth, Thomas Fietz, Dimitri Flieger, Helmut Forstbauer, Werner Freier, Christian Frenzel, Florian Fuchs, Roswitha Fuchs, Thomas Fühner, Tobias Gaska, Wolfgang Gleiber, Tobias Graefe, Ullrich Graeven, Christian Grah, Sibylle Greiner, Frank Griesinger, Christian Grohé, Matthias Groschek, Carolin Groß‐Ophoff‐Müller, Andreas Günther, Sylvia Gütz, Siegfried Haas, Matthias Hackenthal, Volker Hagen, Carla Verena Hannig, Richard Hansen, Andrea Heider, David Heigener, Kathrin Heinrich, Natalia Heinz, Christiane Hering‐Schubert, Jörg Heßling, Conrad Heuchel, Petra Hoffknecht, Patricia Hortig, Gerdt Hübner, Horst‐Dieter Hummel, Ulrich Hutzschenreuter, Gerald Illerhaus, Thomas Illmer, Georg Innig, Melanie Janning, Jan Janssen, Christian Junghanß, Christian Kaes, Ulrich Kaiser, Stefan Kaldune, Haytham Kamal, Kato Kambartel, Lale Kayikci, Jens Kern, Dorothea Kingreen, Ortwin Klein, Konrad Kokowski, Wolfgang Körber, Dirk Koschel, Benoit Krämer, Beate Krammer‐Steiner, Jonas Kuon, Eckart Laack, Christof Lamberti, Markus Lehmann, Rumo David Leistner, Rüdiger Liersch, Hartmut Linde, Migle Link, Jörg Lipke, Verena Luber, Andreas Lück, Gita Maher, Kerstin Martin, Martin Metzenmacher, Christian Meyerzum Büschenfelde, Philipp Meyn, Enno Moorahrend, Christian Mozek, Annette Müller, Lothar Müller, Michael Neise, Holger Nückel, Arnd Nusch, Tobias Overbeck, Matthias Paland, Henning Pelz, Volker Petersen, Bettina Peuser, Christian Plate, Margarete Plath, Stefan Pluntke, Munir Rababah, Martin Reck, Niels Reinmuth, Marcel Reiser, Roland Repp, Daniel Reschke, Achim Rittmeyer, Yolanda Rodemer, Georg Rußwurm, Parvis Sadjadian, Reiner Sandner, Annette Sauer, Harald Schäfer, Clemens Schiefer, Burkhard Schmidt, Stephan Schmitz, Folker Schneller, Jan Schröder, Gunter Schuch, Christoph Schulz, Christian Schulz, Mathias Schulze, Christian Schumann, Wolfgang Schütte, Martin Schwaiblmair, Marcus Schweigert, Peter Florian Schwindt, Martin Sebastian, Bernd Seese, Gernot Seipelt, Christoph Sick, Theodoros Skentos, Thomas Sorgenfrei, Axel Stang, Johannes Steiff, Heike Steiniger, Susanne Stetter, Runa Stiegler, Heidrun Stumme, Amanda Tufman, Jens Uhlig, Ursula Vehling‐Kaiser, Gunther Vogel, Eyck von der Heyde, Oliver Waidmann, Cornelius F. Waller, Georg Weißenborn, Florian Weißinger, Martin Wermke, Claas Wesseler, Jörg Wiegand, Ute Wieschermann, Stefan Wilhelm, Jochen Wilke, Mark‐Oliver Zahn, Matthias Zaiss, Matthias Zeth, Joachim Zimber, Björn Schöttker   +207 more
wiley   +1 more source

Towards an Integrated Staging Model for Bipolar Disorders: An International Society for Bipolar Disorders (ISBD) Staging Task Force Consensus Report

Bipolar Disorders, Volume 28, Issue 5, August 2026.
ABSTRACT Objectives Three clinical staging models for bipolar disorder (BD) have been published, each with a different but complementary approach and focus. The International Society for Bipolar Disorders Staging Task Force aimed to integrate these models into one comprehensive three‐dimensional staging model, separately rating bipolar spectrum ...
Ralph Kupka, Danella Hafeman, Madeleine McCallum, Afra van der Markt, Hailey Tremain, Martin Alda, Jorge Almeida, Taiane de Azevedo Cardoso, Vicent Balanzá‐Martínez, Boris Birmaher, David J. Bond, Elisa Brietzke, Ines Chendo, Iria Grande, Tomas Hajek, Manon Hillegers, Marcia Kauer‐Sant'Anna, Rodrigo Mansur, Ives Cavalcante Passos, Ana Gonzalez Pinto, Robert Post, Mauricio Tohen, Gustavo Vazquez, Eduard Vieta, Lakshmi N. Yatham, Flávio Kapczinski, Michael Berk, Anne Duffy   +27 more
wiley   +1 more source

m1A regulator‑mediated methylation modifications and gene signatures and their prognostic value in multiple myeloma

Experimental and Therapeutic Medicine
N1-methyladenosine (m1A), a methylation of RNA, is gaining attention for its role in diverse biological processes. However, the potential roles of m1A regulatory-mediated methylation modifications in multiple myeloma (MM) remain unclear. The mRNA expression of m1A regulators in normal plasma (NP; n=9) and MM (n=174) bone marrow plasma cells was ...
Fu, Jiaqi, Han, Xingjun, Gao, Wei, Yu, Manya, Cui, Xing   +4 more
openaire   +2 more sources