Results 71 to 80 of about 755,261 (255)

Human annexin A6 interacts with influenza A virus protein M2 and negatively modulates infection [PDF]

, 2011
The influenza A virus M2 ion channel protein has the longest cytoplasmic tail (CT) among the three viral envelope proteins and is well conserved between different viral strains.
Béatrice Nal, François Kien, Ma, H, Kien, F, Leo Lit Man Poon, Zhang, Y, Tse, KS, Poon, LLM, Maniere, M, Nadège Lagarde, Yang Zhang, Maxime Manière, Nal, B, Kong San Tse, Huailiang Ma, Lagarde, N, Ma, Huailiang, Manière, Maxime, Kien, François, Zhang, Yang, Poon, Leo Lit Man, Lagarde, Nadège, Tse, Kong San, Nal, Béatrice   +23 more
core   +1 more source

Identification of potential biomarkers of M2-like macrophage-related genes in HCC.

, 2023
(A) WGCNA identified M2-like macrophage related genes in HCC. (B) Heatmap showing the differentially expressed genes in HCC. (C) The overlap of M2-like macrophage related genes and differentially expressed genes in HCC.
Qian Feng (302178), Linquan Wu (3138357), Hongcheng Lu (1351278)   +2 more
core   +1 more source

Dynamic Loading Regulates Meniscus‐Like Matrix Production in Human Mesenchymal Stromal Cell‐Seeded PET Scaffolds

Advanced Healthcare Materials, EarlyView.
Dynamic compression enhances mesenchymal stromal cell proliferation in nonwoven PET scaffolds under chondrogenic differentiation conditions and triggers mechanosensitive transcriptional programs associated with extracellular matrix remodeling. These findings highlight the potential of mechanically stimulated PET scaffolds as a promising platform for ...
Graciosa Quelhas Teixeira, Luisa de Roy, Anna‐Lotta Feldmeier, Mubashir Ahmad, Sofia Pilão, Maria Ahrens, Anita Ignatius, Carsten Linti, Andreas Martin Seitz   +8 more
wiley   +1 more source

Nanotubular TiO2 regulates macrophage M2 polarization and increases macrophage secretion of VEGF to accelerate endothelialization via the ERK1/2 and PI3K/AKT pathways

, 2019
Wei-Chang Xu,1,* Xiao Dong,1,* Jing-Li Ding,2 Ji-Chun Liu,1 Jian-Jun Xu,1 Yan-Hua Tang,1 Ying-Ping Yi,3 Chao Lu,1 Wei Yang,1 Jue-Sheng Yang,1 Yi Gong,1 Jian-Liang Zhou1 1Department of Cardiovascular Surgery, The Second Affiliated Hospital of Nanchang ...
Yi YP, Yang W, Xu WC, Zhou JL, Dong X, Ding JL, Yang JS, Tang YH, Lu C, Liu JC, Gong Y, Xu JJ   +11 more
core  

Targeting CD300a Signaling With a Phosphatidylserine‐Presenting Hydrogel Rescues Macrophage Dysfunction and Accelerates Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the proposed mechanism: PEG/RGD‐PSLs mimic apoptotic cells to engage PS receptors (notably CD300a), transducing an inhibitory signal that suppresses the MyD88/NF‐κB pathway, leading to global anti‐inflammatory and pro‐reparative effects.
Lele Wu, Xuetong Hao, Yang Zou, Xinglin Chen, Junyan Kong, Chunning Gu, Wenjie Ma, Zhongjun Yang, Huifen Liu, Mengmeng Liu, Xin Tong   +10 more
wiley   +1 more source

Role of macrophages in chronic kidney disease

Linchuang shenzangbing zazhi, 2020
Chronic kidney disease（CKD） has become a major health problem worldwide.This review describes the role of macrophages in CKD and highlights the importance of anti-inflammatory M2 macrophage activation in both renal fibrosis and wound healing processes ...
JIANG Ya-li, LIU Xiao-wei
doaj  

What was behind the M2 breakdown? [PDF]

A deterioration in the link between the M2 monetary aggregate and GDP, along with large errors in predicting M2 growth, led the Board of Governors to downgrade the M2 aggregate as a reliable indicator of monetary policy in 1993.
Cara Lown, Kenneth J. Robinson, Stavros Peristiani   +2 more
core  

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao, Lin Gan, Li Lu, Lizhi Ouyang, Yuan Xiong, Fawwaz Al‐Smadi, Guandong Dai, Mohammad‐Ali Shahbazi, Bobin Mi, Mengfei Liu, Guohui Liu   +10 more
wiley   +1 more source

Artificial intelligence model predicts M2 macrophage levels and HCC prognosis with only globally labeled pathological images

Frontiers in Oncology
Background and aimsThe levels of M2 macrophages are significantly associated with the prognosis of hepatocellular carcinoma (HCC), however, current detection methods in clinical settings remain challenging.
Huiyuan Tian, Yongshao Tian, Dujuan Li, Minfan Zhao, Qiankun Luo, Lingfei Kong, Tao Qin   +6 more
doaj   +1 more source

Transcriptional profiling identifies novel regulators of macrophage polarization.

PLoS ONE, 2018
Macrophages are key inflammatory immune cells that display dynamic phenotypes and functions in response to their local microenvironment. Major advances have occurred in understanding the transcriptional, epigenetic, and functional differences in various ...
Kimberline Y Gerrick, Elias R Gerrick, Anuj Gupta, Sarah J Wheelan, Srinivasan Yegnasubramanian, Elizabeth M Jaffee   +5 more
doaj   +1 more source