Results 11 to 20 of about 879,513 (265)
M2 polarization enhances silica nanoparticle uptake by macrophages [PDF]
Frontiers in Pharmacology, 2015 While silica nanoparticles have enabled numerous industrial and medical applications, their toxicological safety requires further evaluation. Macrophages are the major cell population responsible for nanoparticle clearance in vivo.
Alexandra K Kiemer +21 more
core +3 more sources
Novel Markers to Delineate Murine M1 and M2 Macrophages.
PLoS ONE, 2015 Classically (M1) and alternatively activated (M2) macrophages exhibit distinct phenotypes and functions. It has been difficult to dissect macrophage phenotypes in vivo, where a spectrum of macrophage phenotypes exists, and also in vitro, where low or non-
Lindsay M. Webb +17 more
core +2 more sources
M2 macrophages predict response to neoadjuvant chemotherapy in triple negative breast cancer patients. [PDF]
Sci RepMacrophages, the predominant immune-related stromal cells within tumor microenvironment, could be polarized into M1 and alternative M2 macrophages.
Chen WX +7 more
europepmc +2 more sources
Glomerulonephritis with crescents in childhood; etiologies and significance of M2 macrophages
The Turkish Journal of Pediatrics, 2022 Background. Crescentic glomerulonephritis (CGN) is a rapidly progressive and rare cause of glomerulonephritis in childhood. The aim of this study is to evaluate demographic data of children with crescentic glomerulonephritis, to classify the ...
Gözdem Kaykı +9 more
doaj +1 more source
Inhibitory Prodrug Approach for Selective Elimination of Immunosuppressive M2 Macrophages [PDF]
, 2022 Tumor associated macrophages (TAMs) support tumor development and have emerged as important regulators of therapeutic response to cytostatic agents. To target TAMs, we have developed a novel drug delivery approach which induces drug release in response ...
Martijn, Verdoes +1 more
core +2 more sources
Mathematics in Applied Sciences and Engineering, 2020 Replicating oncolytic viruses provide promising treatment strategies against cancer. However, the success of these viral therapies depends mainly on the complex interactions between the virus particles and the host immune cells. Among these immune cells,
Nada Almuallem, Raluca Eftimie
doaj +1 more source
Induction of unique macrophage subset by simultaneous stimulation with LPS and IL-4
Frontiers in Immunology, 2023 Macrophages manifest as various subtypes that play diverse and important roles in immunosurveillance and the maintenance of immunological homeostasis in various tissues.
Kei Ishida +16 more
doaj +1 more source
Cells, 2020 The role of the innate immune system in ovarian cancer is gaining importance. The relevance of tumor-associated macrophages (TAM) is insufficiently understood.
Ann Vankerckhoven +8 more
doaj +1 more source
M1/M2 macrophages and their overlaps – myth or reality? [PDF]
, 2023 Macrophages represent heterogeneous cell population with important roles in defence mechanisms and in homoeostasis. Tissue macrophages from diverse anatomical locations adopt distinct activation states.
Cecrdlova, Eva +6 more
core +1 more source
PLoS Pathogens, 2020 After HSV-1 infection, macrophages infiltrate early into the cornea, where they play an important role in HSV-1 infection. Macrophages are divided into M1 or M2 groups based on their activation.
Ujjaldeep Jaggi +6 more
doaj +1 more source