Results 21 to 30 of about 879,513 (265)

"Re-educating" tumor-associated macrophages by targeting NF-kappaB [PDF]

, 2008
The nuclear factor kappaB (NF-kappaB) signaling pathway is important in cancer-related inflammation and malignant progression. Here, we describe a new role for NF-kappaB in cancer in maintaining the immunosuppressive phenotype of tumor-associated ...
Balkwill, F.R., Mcneish, I., Kellie A. Charles, Thorsten Hagemann, Robinson, S.C., Hagemann, T, Charles, KA, Balkwill, FR, Hagemann, T., Charles, K.A., Iain McNeish, Kulbe, H., Lawrence, T., McNeish, I, Robinson, SC, Thompson, RG, Hagen Kulbe, Richard G. Thompson, Frances R. Balkwill, Stephen C. Robinson, Toby Lawrence, Thompson, R.G., Lawrence, T, Kulbe, H   +23 more
core   +1 more source

Potential injurious effects of the fine particulate PM2.5 on the progression of atherosclerosis in apoE-deficient mice by activating platelets and leukocytes

Archives of Medical Science, 2018
Introduction Exposure to the fine particulate matter PM2.5 is strongly associated with atherosclerotic diseases, creating considerable public concern. Nevertheless, the mechanisms have not been fully elucidated.
Xuecan Zhu, Pei Zhao, Yonggang Lu, Lijing Huo, Mingchen Bai, Fang Yu, Yanqing Tie   +6 more
doaj   +1 more source

Decidual Macrophages Are Significantly Increased in Spontaneous Miscarriages and Over-Express FasL [PDF]

, 2012
Decidual macrophages (DM) are the second most abundant population in the fetal-maternal interface. Their role has been so far identified as being local immuno-modulators favoring the maternal tolerance to the fetus.
Iordanis Navrozoglou, Darius Dian, Antonis Makrigiannakis, Sabine Guenther, Anz, David, Jeschke, Udo, Klaus Friese, Udo Jeschke, Thomas Vrekoussis, Vrekoussis, Thomas, Knabl, Julia, Dian, Darius, Julia Knabl, Bayer, Birgit, Heublein, Sabine, Navrozoglou, Iordanis, Friese, Klaus, Sabine Heublein, Makrigiannakis, Antonis, David Anz, Guenther, Sabine, Birgit Bayer   +21 more
core   +1 more source

Preferential stimulation of melanocytes by M2 macrophages to produce melanin through vascular endothelial growth factor

Scientific Reports, 2022
Post-inflammatory hyperpigmentation is a skin discoloration process that occurs following an inflammatory response or wound. As the skin begins to heal, macrophages first exhibit a proinflammatory phenotype (M1) during the early stages of tissue repair ...
Heeju Han, Yena Kim, Hyunkyung Mo, Si Hwa Choi, Kijun Lee, Yeri Alice Rim, Ji Hyeon Ju   +6 more
doaj   +1 more source

Human annexin A6 interacts with influenza A virus protein M2 and negatively modulates infection [PDF]

, 2011
The influenza A virus M2 ion channel protein has the longest cytoplasmic tail (CT) among the three viral envelope proteins and is well conserved between different viral strains.
Béatrice Nal, François Kien, Ma, H, Kien, F, Leo Lit Man Poon, Zhang, Y, Tse, KS, Poon, LLM, Maniere, M, Nadège Lagarde, Yang Zhang, Maxime Manière, Nal, B, Kong San Tse, Huailiang Ma, Lagarde, N, Ma, Huailiang, Manière, Maxime, Kien, François, Zhang, Yang, Poon, Leo Lit Man, Lagarde, Nadège, Tse, Kong San, Nal, Béatrice   +23 more
core   +1 more source

Donor‐derived M2 macrophages attenuate GVHD after allogeneic hematopoietic stem cell transplantation

Immunity, Inflammation and Disease, 2021
Introduction Graft‐versus‐host disease (GVHD) is frequent and fatal complication following allogeneic hematopoietic stem cell transplantation (HSCT) and characteristically involves skin, gut, and liver. Macrophages promote tissue regeneration and mediate
Ryo Hanaki, Hidemi Toyoda, Shotaro Iwamoto, Mari Morimoto, Daisuke Nakato, Takahiro Ito, Kaori Niwa, Keishiro Amano, Ryotaro Hashizume, Isao Tawara, Masahiro Hirayama   +10 more
doaj   +1 more source

Intrahepatic cholangiocarcinoma induced M2-polarized tumor-associated macrophages facilitate tumor growth and invasiveness

Cancer Cell International, 2020
Background M2-polarized tumor-associated macrophages (M2-TAMs) have been shown to correlate with the progression of various cancers, including intrahepatic cholangiocarcinoma (ICC).
Hui Yuan, Zelong Lin, Yingjun Liu, Yuchuan Jiang, Ke Liu, Mengxian Tu, Nan Yao, Chen Qu, Jian Hong   +8 more
doaj   +1 more source

Macrophages and ym1⁺ M2 macrophages.

, 2022
(A) Immunofluorescence staining with Alexa Fluor 488 (green; anti-mac-3 antibody), Alexa Fluor 647 (pink; anti-ym1 antibody), and DAPI (blue) were observed on day 7.
Yukari Nakajima (67614), Shin-ichi Horike (2178772), Toshio Nakatani (457543), Kanae Mukai (676017), Makiko Meguro-Horike (28674), Arya Iswara (12225073)   +5 more
core   +1 more source

Expression of the Inhibitory CD200 Receptor Is Associated with Alternative Macrophage Activation [PDF]

, 2010
Classical macrophage activation is inhibited by the CD200 receptor (CD200R). Here, we show that CD200R expression was specifically induced on human in vitro polarized macrophages of the alternatively activated M2a subtype, generated by incubation with IL-
Brouwer, Michael S. M., Huitinga, I., Voehringer, David, Raes, G., van Eijk, Marco, Hoek, Robert M., Hamann, J., Huitinga, Inge, Koning, N., Brouwer, M.S., Raes, Geert, Pouwels, W., Voehringer, D., Koning, Nathalie, Van Eijk, M., Hoek, R.M., Pouwels, Walter, Hamann, Jörg   +17 more
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Exosomes derived from reparative M2-like macrophages prevent bone loss in murine periodontitis models via IL-10 mRNA

Journal of Nanobiotechnology, 2022
Background Periodontitis is characterized by progressive inflammation and alveolar bone loss resulting in tooth loss finally. Macrophages including pro-inflammatory M1-like macrophages and reparative M2-like macrophages play a vital role in inflammation ...
Xutao Chen, Zhuo Wan, Liu Yang, Shuang Song, Zhaoyue Fu, Kang Tang, Lihua Chen, Yingliang Song   +7 more
doaj   +1 more source