Results 111 to 120 of about 26,139 (253)

Complete genome sequence of the Clostridium difficile laboratory strain 630Δerm reveals differences from strain 630, including translocation of the mobile element CTn5 [PDF]

, 2015
Molecular Technology and Informatics for Personalised Medicine and ...
Adam P Roberts, Arnoud M Schmitz, Erika van Eijk, Hilary P Browne, Jeroen Frank, Seyed Anvar, Wai Leung, Wiep Smits   +7 more
core   +1 more source

Advanced extracellular vesicle immunotherapy

FlexMat, EarlyView.
A diagrammatic depiction of the therapeutic applicability of extracellular vesicles (EVs) in immunotherapy. This review explores the dual roles of tumor‐derived and immune cell‐derived EVs in cancer immunotherapy, discusses recent progress in EV engineering that improve their clinical utility, and evaluates their potential to augment existing ...
Jingjing Zhang, Yunfei Mu, Xianyue Ji, Xiaoting Jiang, Ruiheng Wang, Xianguang Ding, Lianhui Wang   +6 more
wiley   +1 more source

Nuclear localised more sulphur accumulation1 epigenetically regulates sulphur homeostasis in Arabidopsis thaliana [PDF]

, 2016
Sulphur (S) is an essential element for all living organisms. The uptake, assimilation and metabolism of S in plants are well studied. However, the regulation of S homeostasis remains largely unknown.
A Becker, A Goyer, A Maruyama-Nakashita, A Maruyama-Nakashita, A Maruyama-Nakashita, AD Hanson, AD Hanson, AF Pendle, AM Catanzariti, Anna Koprivova, B Lahner, B Shane, BR Lee, Brian Dilkes, CG Kawashima, CG Kawashima, D Gorlich, D Mao, D Secco, Dai-Yin Chao, David E Salt, DY Chao, Francisco J. Sandoval, G Liang, G Tsakraklides, GZ Luo, H Bauwe, H Rouached, H Takahashi, H Takahashi, H Tian, H Zhang, Hermann Bauwe, HM Hubberten, HR Zhou, JA Law, John Danku, K Arnold, K Burstenbinder, L Schirch, L Yong-Villalobos, L Yong-Villalobos, LM Voll, M Barberon, M Bielecka, M Eisenhut, M Sauter, Markus Wirtz, MW Jones-Rhoades, MY Hirai, N Engel, N Guex, N Terry, N Yoshimoto, N Yoshimoto, PP Sahu, PS Hosmani, RT Taylor, Rüdiger Hell, S Alfadhli, S Kosugi, S Lee, S Li, S Liu, Sanja Roje, SG Mugford, SJ Clough, Stanislav Kopriva, Steffen Müller, T Fujiwara, T Kamiya, T Leustek, T Matsushita, TF Fu, Thomas Leustek, TT Calikowski, V Chinnusamy, V Schirch, W Huang da, W Wen, WA Loenen, X Zhang, Xin-Yuan Huang, XY Huang, XY Huang, Y Hacham, Y Wan, Y Xi, Y Zhang, Y Zhang, Z Wei   +90 more
core   +3 more sources

Tumor‐educated platelets in cancer diagnostics and prognostics: A critical appraisal and roadmap for clinical translation

International Journal of Cancer, EarlyView.
Abstract Tumor‐educated platelets (TEPs) are emerging as a compelling frontier in liquid biopsy, functioning as dynamic, systemic sensors that sequester and process tumor‐derived biomolecules. This interaction imprints an integrated molecular signature of malignancy—spanning the transcriptome, proteome, lipidome, and crucially, the captured genome ...
Whi‐An Kwon, Min‐Kyung Lee, Eunyong Ahn, Heeyeon Kim, Yong Sang Song, Taejin Ahn   +5 more
wiley   +1 more source

Transcriptome-Wide High-Throughput m6A Sequencing of Differential m6A Methylation Patterns in the Human Rheumatoid Arthritis Fibroblast-Like Synoviocytes Cell Line MH7A

Journal of Inflammation Research, 2021
Hui Jiang1,2 *,* Kefeng Cao3 *,* Chang Fan,1,2 Xiaoya Cui,1,2 Yanzhen Ma,1,2 Jian Liu1 1Experimental Center of Clinical Research, First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, Anhui, People’s Republic of China; 2School ...
Jiang H, Cao K, Fan C, Cui X, Ma Y, Liu J   +5 more
doaj  

-methyladenosine (mA)-circHECA from secondary hair follicle of cashmere goats: identification, regulatory network and expression regulated potentially by methylation of its host gene promoter [PDF]

Animal Bioscience
Objective The objective of this study was to identify the N6-methyladenosine (m6A)-circHECA molecule in secondary hair follicles (SHFs) of cashmere goats, and generate its potential regulatory network, as well as explore the potential relationship ...
Jincheng Shen, Taiyu Hui, Man Bai, Yixing Fan, Yubo Zhu, Qi Zhang, Ruqing Xu, Jialiang Zhang, Zeying Wang, Wenxin Zheng, Wenlin Bai   +10 more
doaj   +1 more source

Role of FTO in adipocyte development and function: recent insights [PDF]

, 2015
In 2007, FTO was identified as the first genome-wide association study (GWAS) gene associated with obesity in humans. Since then, various animal models have served to establish the mechanistic basis behind this association.
Merkestein, Myrte, Sellayah, Dyan
core   +2 more sources

Regulatory mechanisms of m6A methylation in dilated cardiomyopathy

American Journal of Translational Research
Dilated cardiomyopathy (DCM) is a complex heart condition marked by genetic mutations, myocardial dysfunction, and progressive heart failure. N6-methyladenosine (m6A) methylation, a key epigenetic modification, plays a crucial role in DCM by regulating gene expression in various pathologic processes, including cardiomyocyte death, inflammation ...
Hao, Zhang, Haiyang, Guo, Fengjiao, Han, Yang, Zheng   +3 more
openaire   +2 more sources

Endometrial Stromal Cell Senescence: A Non‐Negligible Factor in Recurrent Pregnancy Loss

iMetaMed, EarlyView.
As populations age, links between female reproductive aging and infertility are increasingly evident. Cellular senescence, characterized by near‐irreversible cell‐cycle arrest and accumulation of damage, can impair tissue function. In the endometrium, aberrant senescence of endometrial stromal cells (EnSCs) may compromise receptivity, hinder embryo ...
Shuang Wu, Cenlan Bu, Qinzheng Xu, Xi Cheng, Junrong Zhang, Jinling Chen, Yun‐Zhao Xu   +6 more
wiley   +1 more source

Cytosine methylated DNA synthesized by Taq polymerase used to assay methylation sensitivity of restriction endonuclease HinfI [PDF]

, 1991
We have studied the resistance of cytosine methylated DNA to digestion by the restriction endonuclease HinfI, using a simple PCR procedure to synthesize DNA of known sequence in which every cytosine is methylated at the 5 position.
Colasanti, J., Sundaresan, V.
core   +1 more source