Results 1 to 10 of about 181,163 (261)
Epigenetic modifications in neuropathic pain [PDF]
Molecular Pain, 2021 Neuropathic pain (NP) is a common symptom in many diseases of the somatosensory nervous system, which severely affects the patient’s quality of life. Epigenetics are heritable alterations in gene expression that do not cause permanent changes in the DNA ...
Danzhi Luo +7 more
doaj +3 more sources
Role of epigenetic modification in interferon treatment of hepatitis B virus infection
Frontiers in Immunology, 2022 Human hepatitis B virus (HBV) is a small, enveloped DNA virus that causes acute and chronic hepatitis. Chronic hepatitis B (CHB) is associated with hepatocellular carcinoma pathogenesis.
Zhijing Yang +17 more
doaj +1 more source
Epigenetic alterations in female urogenital organs cancer: Premise, properties, and perspectives
Scientific African, 2020 Cancer is a sickness, initiated and driven via accumulation and interaction of genetic and epigenetic modification of genes involved in regulation of cell communication, signaling and growth division.
Abdelkareem A. Ahmed +1 more
doaj +1 more source
RETRACTED: The Emerging Role of Epigenetics in Metabolism and Endocrinology
Biology, 2023 Each cell in a multicellular organism has its own phenotype despite sharing the same genome. Epigenetics is a somatic, heritable pattern of gene expression or cellular phenotype mediated by structural changes in chromatin that occur without altering the ...
Belay Zeleke Sibuh +8 more
doaj +1 more source
Epigenetic editing for autosomal dominant neurological disorders
Frontiers in Genome EditingEpigenetics refers to the molecules and mechanisms that modify gene expression states without changing the nucleotide context. These modifications are what encode the cell state during differentiation or epigenetic memory in mitosis.
Jennifer J. Waldo +2 more
doaj +1 more source
A global genome segmentation method for exploration of epigenetic patterns. [PDF]
PLoS ONE, 2012 Current genome-wide ChIP-seq experiments on different epigenetic marks aim at unraveling the interplay between their regulation mechanisms. Published evaluation tools, however, allow testing for predefined hypotheses only. Here, we present a novel method
Lydia Steiner +6 more
doaj +1 more source
Role of RNA N6-Methyladenosine Modification in Male Infertility and Genital System Tumors
Frontiers in Cell and Developmental Biology, 2021 Epigenetic alterations, particularly RNA methylation, play a crucial role in many types of disease development and progression. Among them, N6-methyladenosine (m6A) is the most common epigenetic RNA modification, and its important roles are not only ...
Shuai Liu +13 more
doaj +1 more source
Epigenetic regulation in the tumor microenvironment: molecular mechanisms and therapeutic targets
Signal Transduction and Targeted Therapy, 2023 Over decades, researchers have focused on the epigenetic control of DNA-templated processes. Histone modification, DNA methylation, chromatin remodeling, RNA modification, and noncoding RNAs modulate many biological processes that are crucial to the ...
Jing Yang +5 more
doaj +1 more source
Acta Pharmaceutica Sinica BLiver fibrosis, characterized by scar tissue formation, can ultimately result in liver failure. It's a major cause of morbidity and mortality globally, often associated with chronic liver diseases like hepatitis or alcoholic and non-alcoholic fatty liver
Runping Liu +5 more
doaj +1 more source
Research progress and applications of epigenetic biomarkers in cancer
Frontiers in PharmacologyEpigenetic changes are heritable changes in gene expression without changes in the nucleotide sequence of genes. Epigenetic changes play an important role in the development of cancer and in the process of malignancy metastasis.
Jianjun Gao +13 more
doaj +1 more source