Results 11 to 20 of about 181,163 (261)
Epigenetic modification in Parkinson’s disease [PDF]
Frontiers in Cell and Developmental Biology, 2023 Parkinson’s disease (PD) is a common neurodegenerative disorder caused by genetic, epigenetic, and environmental factors. Recent advance in genomics and epigenetics have revealed epigenetic mechanisms in PD.
Hao Song +17 more
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Epigenetic modifications in the accumulation and function of myeloid-derived suppressor cells
Frontiers in Immunology, 2022 Myeloid-derived suppressor cells (MDSCs) are key players under various pathologic conditions, such as cancer. Epigenetic modifications such as DNA methylation, RNA-mediated processes, and histone modification can alter gene transcription, and thus ...
Liangjie Xu +6 more
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Frontiers in Oncology, 2021 BackgroundIncreasing evidence has indicated that abnormal epigenetic factors such as RNA m6A modification, histone modification, DNA methylation, RNA binding proteins and transcription factors are correlated with hepatocarcinogenesis.
Maoqing Lu +5 more
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Epigenetic Modifications and Therapy in Uveitis [PDF]
Frontiers in Cell and Developmental Biology, 2021 Uveitis is a sight-threatening intraocular inflammation, and the exact pathogenesis of uveitis is not yet clear. Recent studies, including multiple genome-wide association studies (GWASs), have identified genetic variations associated with the onset and progression of different types of uveitis, such as Vogt–Koyanagi–Harada (VKH) disease and Behcet’s ...
Yanli Zou +7 more
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Readout of Epigenetic Modifications [PDF]
Annual Review of Biochemistry, 2013 This review focuses on a structure-based analysis of histone posttranslational modification (PTM) readout, where the PTMs serve as docking sites for reader modules as part of larger complexes displaying chromatin modifier and remodeling activities, with the capacity to alter chromatin architecture and templated processes.
Dinshaw J, Patel, Zhanxin, Wang
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Editorial: Epigenetic modification in neurological diseases [PDF]
Frontiers in GeneticsMojgan Rastegar
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Research progress of immune response regulated by epigenetic modification in pneumonia
Shanghai Jiaotong Daxue xuebao. Yixue ban, 2023 Pneumonia is one of the most common infectious diseases, and although considerable progress has been made in the diagnosis and treatment of pneumonia, it is still associated with high mortality, prolonged hospitalization, and significant medical ...
WANG Qing, HAN Xiao, ZHANG Xiaobo
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Epigenetic modifications in cancer [PDF]
Clinical Genetics, 2011 Kanwal R, Gupta S. Epigenetic modifications in cancer.Cancer initiation and progression is controlled by both genetic and epigenetic events. The complexity of carcinogenesis cannot be accounted for by genetic alterations alone but also involves epigenetic changes. Epigenetics refers to the study of mechanisms that alter gene expression without altering
R, Kanwal, S, Gupta
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Epigenetics: Novel crucial approach for osteogenesis of mesenchymal stem cells
Journal of Tissue Engineering, 2023 Bone has a robust regenerative potential, but its capacity to repair critical-sized bone defects is limited. In recent years, stem cells have attracted significant interest for their potential in tissue engineering. Applying mesenchymal stem cells (MSCs)
Zhaohua Wang +8 more
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Epigenetic Regulation in Pathology of Atherosclerosis: A Novel Perspective
Frontiers in Genetics, 2021 Atherosclerosis, characterized by atherosclerotic plaques, is a complex pathological process that involves different cell types and can be seen as a chronic inflammatory disease.
Haishuang Tang +4 more
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