Results 21 to 30 of about 181,163 (261)
Dysregulated epigenetic modifications in psoriasis [PDF]
Experimental Dermatology, 2021 AbstractThe observed incidence of psoriasis has been gradually increasing over time (J Am Acad Dermatol, 03, 2009, 394), but the underlying pathogenic factors have remained unclear. Recent studies suggest the importance of epigenetic modification in the pathogenesis of psoriasis.
Chang Zeng +2 more
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Crosstalk between epigenetic modification and circRNA in colorectal cancer: recent advances
Shanghai Jiaotong Daxue xuebao. Yixue ban, 2023 Colorectal cancer (CRC) is generally regarded as the third frequent malignancy worldwide, while current diagnosis and treatment of the disease are limited.
PENG Tian, XU Leiming
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Transcription factors direct epigenetic reprogramming at specific loci in human cancers
Frontiers in Genetics, 2023 The characterization of epigenetic changes during cancer development and progression led to notable insights regarding the roles of cancer-specific epigenetic reprogramming.
Han Jiang, Guoxin Li
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Small-Molecule Inhibitors Overcome Epigenetic Reprogramming for Cancer Therapy
Frontiers in Pharmacology, 2021 Cancer treatment is a significant challenge for the global health system, although various pharmacological and therapeutic discoveries have been made.
Wenjing Xiao +11 more
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Epigenetic modifications as therapeutic targets [PDF]
Nature Biotechnology, 2010 Epigenetic modifications work in concert with genetic mechanisms to regulate transcriptional activity in normal tissues and are often dysregulated in disease. Although they are somatically heritable, modifications of DNA and histones are also reversible, making them good targets for therapeutic intervention.
Kelly, Theresa K +2 more
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Frontiers in Physiology, 2023 Skeletal muscles, the largest organ responsible for energy metabolism in most mammals, play a vital role in maintaining the body’s homeostasis.
Junjie Xu, Chenglong Li, Xiaolong Kang
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Change of epigenetic modification and human reproduction
Asian Pacific Journal of Reproduction, 2016 In recent years, it has become consumedly clear that changing of epigenetic modification is essential during both early and late oogenesis and spermatogenesis. Also epigenetic modifications are involved in some cases such as embryo development and growth,
Jafar Nouri Nojadeh, Hossein Daghghagh
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Epigenetic modification and BRAF gene mutation in thyroid carcinoma
Cancer Cell International, 2021 Thyroid cancer remains the most prevailing endocrine malignancy, and a progressively increasing incidence rate has been observed in recent years, with 95% of thyroid cancer represented by differentiated thyroid carcinomas. The genetics and epigenetics of
Guo Huang +6 more
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Editorial: Epigenetic Modifications in Mesothelioma [PDF]
Frontiers in Oncology, 2021 We are pleased to announce the publication of this Research Topic focusing on epigenetic modifications in mesothelioma. Epigenetic modification has been investigated for the past two decades. It is a key process of cellular development as well as carcinogenesis.
Yuen Yee Cheng +2 more
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Fruit development and epigenetic modifications [PDF]
New Phytologist, 2020 SummaryFruit development is a complex process that is regulated not only by plant hormones and transcription factors, but also requires epigenetic modifications. Epigenetic modifications include DNA methylation, histone post‐translational modifications, chromatin remodeling and noncoding RNAs.
Tang, Dengguo +2 more
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