Results 271 to 280 of about 1,875,792 (320)
METTL16 Contributes to Coronary Heart Disease by Inducing TET2 m6A Modification. [PDF]
Ruan R, Zhang Y.
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Molecular Cell, 2023
In the cytoplasm, mRNAs are dynamically partitioned into translating and non-translating pools, but the mechanism for this regulation has largely remained elusive.
Yafen, Yu Zhou
exaly +2 more sources
In the cytoplasm, mRNAs are dynamically partitioned into translating and non-translating pools, but the mechanism for this regulation has largely remained elusive.
Yafen, Yu Zhou
exaly +2 more sources
Current Insights into Obesity and m6A Modification
Obesity has emerged as a global health challenge, closely associated with multiple metabolic diseases, such as cardiovascular diseases, type 2 diabetes, and non-alcoholic fatty liver disease.
Chen Meng, Di Yang
semanticscholar +3 more sources
The roles and implications of RNA m6A modification in cancer
Nature Reviews Clinical Oncology, 2023Xiaolan Deng, Ying Qing, Huilin Huang
exaly +2 more sources
Modulation of circRNA Metabolism by m6A Modification [PDF]
N6-methyladenosine (m6A) is an RNA modification well-known for its contribution to different processes controlling RNA metabolism, including splicing, stability, and translation of mRNA. Conversely, the role of m6A on the biogenesis and function of circular RNAs (circRNAs) has yet to be addressed.
Gaia Di TIMOTEO +2 more
exaly +4 more sources
N6‐methyladenosine (m6A) Modification in Preeclampsia
Reproductive Sciences, 2023Recently, epitranscriptional modification of N6-methyladenosine (m6A) has received growing attention in the research on the pathogenesis of preeclampsia. Advances in m6A sequencing have revealed the molecular mechanism and importance of m6A modification.
Tingting Zhang +6 more
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RNA m6A modification meets plant hormones
Nature PlantsPlant hormones are essential signalling molecules that control and coordinate diverse physiological processes in plant development and adaptation to ever-fluctuating environments. This hormonal regulation of plant development and environmental responses has recently been shown to extensively involve the most widespread RNA modification, N6 ...
Lisha Shen, Hao Yu
semanticscholar +3 more sources
The role of m6A modification in pediatric cancer
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2022With the development of RNA modification research, the importance of N6-methyladenosine (m6A) in tumors cannot be ignored. m6A promotes the self-renewal of tumor stem cells and the proliferation of tumor cells. It affects post-transcriptional gene expression through epigenetic mechanisms, combining various factors to determine proteins' fate and ...
Yongping, Chen +4 more
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Exploring the role of m6A modification in cancer
PROTEOMICS, 2022Abstract m6A is one of the most common, abundant, and conserved post‐transcriptional modifications that regulate broad biological processes in the human body through m6A regulators. m6A regulators are figuratively classified according to their functions: writers, erasers, and readers, which can methylate RNAs, demethylate RNAs, and ...
Yongqi Wei, Yin Li, Chunlai Lu
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