Results 11 to 20 of about 937,277 (225)
m6A RNA methylation attenuates thermotolerance in Arabidopsis
bioRxivHeat stress severely affects plant growth, causing significant crop yield losses. To counteract this, plants employ adaptive strategies, including chromatin and transcriptional regulation of heat stress-related genes. However, the role of RNA methylation
Kirti Shekhawat +6 more
semanticscholar +4 more sources
The role of RNA m6A methylation in lipid metabolism
Frontiers in Endocrinology, 2022 The m6A methylation is the most numerous modification of mRNA in mammals, coordinated by RNA m6A methyltransferases, RNA m6A demethylases, and RNA m6A binding proteins. They change the RNA m6A methylation level in their specific manner.
Yuting Wang +5 more
doaj +3 more sources
The role of m6A RNA methylation in cancer metabolism [PDF]
Molecular Cancer, 2022 Metabolic reprogramming is one of the main characteristics of malignant tumors, which is due to the flexible changes of cell metabolism that can meet the needs of cell growth and maintain the homeostasis of tissue environments.
Yuan-Yuan An, Huayan Duan
semanticscholar +4 more sources
The Critical Role of RNA m6A Methylation in Cancer [PDF]
Cancer Research, 2019 Abstract Since the identification of the first RNA demethylase and the establishment of methylated RNA immunoprecipitation-sequencing methodology 6 to 7 years ago, RNA methylation has emerged as a widespread phenomenon and a critical regulator of transcript expression. This new layer of regulation is termed “epitranscriptomics.” The most
Lan, Q +5 more
openaire +5 more sources
The role of m6A RNA methylation in cancer.
Biomedicine & Pharmacotherapy, 2019 N6-methyladenosine (m6A), the most abundant internal modification of RNA in eukaryotic cells, has gained increasing attention in recent years. The m6A modification affects multiple aspects of RNA metabolism, ranging from RNA processing, nuclear export ...
Tingyi Sun, Rui-Yan Wu, Ming Liang
semanticscholar +3 more sources
Changes in m6A RNA methylation contribute to heart failure progression by modulating translation
European Journal of Heart Failure, 2019 Deregulation of epigenetic processes and aberrant gene expression are important mechanisms in heart failure. Here we studied the potential relevance of m6A RNA methylation in heart failure development.
Tea Berulava +18 more
semanticscholar +2 more sources
The roles and mechanism of m6A RNA methylation regulators in cancer immunity.
Biomedicine & Pharmacotherapy, 2023 N6-methyladenosine (m6A), the most common internal modification in RNA, can be regulated by three types of regulators, including methyltransferases (writers), demethylases (erasers), and m6A binding proteins (readers). Recently, immunotherapy represented
Lu Chen +11 more
semanticscholar +3 more sources
The role of m6A RNA methylation in human cancer [PDF]
Molecular Cancer, 2019 N6-methyladenosine (m6A) is identified as the most common, abundant and conserved internal transcriptional modification, especially within eukaryotic messenger RNAs (mRNAs).
Xiao-Yu Chen, Jing Zhang, Jin-Shui Zhu
semanticscholar +4 more sources
The interplay between m6A RNA methylation and noncoding RNA in cancer
Journal of Hematology & Oncology, 2019 N6-methyladenosine (m6A) methylation, one of the most common RNA modifications, has been reported to execute important functions that affect normal life activities and diseases.
Shuai Ma +8 more
semanticscholar +4 more sources
A Role for m6A RNA Methylation in Heart Failure Development? [PDF]
European Journal of Heart Failure, 2019 This article refers to ‘Changes in m6A RNA methylation contribute to heart failure progression by modulating translation’ by T. Berulava et al., published in this issue on pages 54–66.
Yvan, Devaux, Anne Yaël, Nossent
openaire +4 more sources