Results 41 to 50 of about 937,277 (225)
The m6A-related gene signature for predicting the prognosis of breast cancer [PDF]
PeerJ, 2021 N6-methyladenosine (m6A) modification has been shown to participate in tumorigenesis and metastasis of human cancers. The present study aimed to investigate the roles of m6A RNA methylation regulators in breast cancer.
Shanliang Zhong +5 more
doaj +2 more sources
Interaction between m6A methylation and noncoding RNA in glioma
Cell Death Discovery, 2022 AbstractGlioma is considered to be the most common brain malignancy in the central nervous system. At present, the aetiology of glioma is not clear. Due to its rapidly growth and easily recurrence, the prognosis of patients with glioma is very poor.
Nairong Tao +5 more
openaire +3 more sources
Frontiers in Oncology, 2019 N6-methyladenosine (m6A) is the most common form of mRNA modification, and is dynamically regulated by the m6A RNA methylation regulators. However, little is known about m6A in gastric cancer. The aim of this work is to investigate the effects of m6A RNA
Yunshu Su, Jinqi Huang, Jichang Hu
doaj +1 more source
RNA m6A methylation regulators in endometrial cancer (Review)
International Journal of Oncology, 2022 As one of the three major malignant tumor types of the female reproductive system, endometrial cancer (EC) is the most prevalent gynecologic cancer in developed countries. In recent years, the incidence of EC has increased worldwide, threatening the health and well‑being of women.
Shen, Siyi +4 more
openaire +2 more sources
m6A RNA methylation modulates antiviral response in celiac disease. [PDF]
Genes ImmunN6-methyladenosine (m6A) RNA modifications and reovirus infections have recently been implicated in the development of celiac disease. While viral infections are known to alter the RNA modification machinery of the host, their interplay in autoimmune tissue damage remains unexplored.
Sebastian-delaCruz M +11 more
europepmc +3 more sources
Molecular Cancer, 2021 The m 6 A RNA methylation is the most prevalent internal modification in mammalian mRNAs which plays critical biological roles by regulating vital cellular processes.
M. Uddin, Zhishan Wang, Cheng-Feng Yang
semanticscholar +1 more source
Abnormality of m6A mRNA Methylation Is Involved in Alzheimer’s Disease
Frontiers in Neuroscience, 2020 Alzheimer’s disease (AD), the most common form of dementia, is highly prevalent in older adults. The main clinical feature is the progressive decline of memory function, which eventually leads to the decline of cognitive function.
Min Han +7 more
doaj +1 more source
Frontiers in Genetics, 2021 Background: N6-Methyladenosine (m6A) methylation is the most prevalent internal posttranscriptional modification on mammalian mRNA. But its role in neuromyelitis optica spectrum disorders (NMOSD) is not known.Aims: To explore the mechanism of m6A in ...
Hong Yang +7 more
doaj +1 more source
m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells
Cell Reports, 2017 Summary RNA modifications play critical roles in important biological processes. However, the functions of N6-methyladenosine (m6A) mRNA modification in cancer biology and cancer stem cells remain largely unknown. Here, we show that m6A mRNA modification
Qi Cui +12 more
semanticscholar +1 more source
Journal of Hematology & Oncology, 2022 The tumor microenvironment (TME), which is regulated by intrinsic oncogenic mechanisms and epigenetic modifications, has become a research hotspot in recent years.
Fusheng Zhang +8 more
semanticscholar +1 more source