Results 51 to 60 of about 2,779 (193)

Multiplex Degenerate Primer Design for Targeted Whole Genome Amplification of Many Viral Genomes

Advances in Bioinformatics, Volume 2014, Issue 1, 2014., 2014
Background. Targeted enrichment improves coverage of highly mutable viruses at low concentration in complex samples. Degenerate primers that anneal to conserved regions can facilitate amplification of divergent, low concentration variants, even when the strain present is unknown. Results.
Shea N. Gardner, Crystal J. Jaing, Maher M. Elsheikh, José Peña, David A. Hysom, Monica K. Borucki, Paul Harrison   +6 more
wiley   +1 more source

Comparison of Vaccine Platforms for Machupo Virus

Vaccines
Background/Objectives: Pathogenic mammarenaviruses cause severe hemorrhagic and neurologic disease in humans. Machupo virus (MACV), a New World (NW) mammarenavirus, causes Bolivian hemorrhagic fever in humans, and there are no approved vaccines. Methods:
Rachel Erickson, Hiromi Muramatsu, Sachchidanand Tiwari, Sowmya Sriram, Fernanda Caroline Coirada, Norbert Pardi, Paul Bates   +6 more
doaj   +1 more source

Interaction of silver nanoparticles with Tacaribe virus [PDF]

, 2010
Background Silver nanoparticles possess many unique properties that make them attractive for use in biological applications. Recently they received attention when it was shown that 10 nm silver nanoparticles were bactericidal, which is ...
Janice L Speshock, Richard C Murdock, Laura K Braydich-Stolle, Amanda M Schrand, Saber M Hussain   +4 more
core   +2 more sources

Urgent pandemic messaging of WHO, World Bank, and G20 is inconsistent with their evidence base

Global Policy, Volume 15, Issue 4, Page 689-707, September 2024.
Abstract When international agencies make claims of an “existential threat” to humanity and advocate for urgent action from countries, it should be a safe assumption that they are consistent with their own data. However, a review of the data and evidentiary citations underlying the claims of the World Health Organization (WHO), the World Bank, and the ...
David Bell, Garrett Wallace Brown, Jean von Agris, Blagovesta Tacheva   +3 more
wiley   +1 more source

Arenavirus Budding

Advances in Virology, Volume 2011, Issue 1, 2011., 2011
Several arenaviruses cause hemorrhagic fever disease in humans and pose a significant public health concern in their endemic regions. On the other hand, the prototypic arenavirus LCMV is a superb workhorse for the investigation of virus‐host interactions and associated disease.
Shuzo Urata, Juan Carlos de la Torre, Fadila Bouamr   +2 more
wiley   +1 more source

Multifunctional Mobile Module Complex for Analysis of Pathogenic Biological Materials (Agents)

Вестник войск РХБ защиты, 2023
Multifunctional mobile module complex for analysis of pathogenic biological materials (agents) (MKA PBA) and for the support of the decisions of the operational groups of the Ministry of Defence of Russia in case of biological emergencies, has been ...
M. V. Supotnitskiy
doaj   +1 more source

Expression and Purification of Z Protein from Junín Virus

BioMed Research International, Volume 2010, Issue 1, 2010., 2010
Arenaviridae comprises 23 recognized virus species with a bipartite ssRNA genome and an ambisense coding strategy. The virions are enveloped and include nonequimolar amounts of each genomic RNA species, designated L and S, coding for four ORFs (N, GPC, L, and Z).
S. E. Goñi, C. S. Borio, F. B. Romano, R. P. Rota, M. G. Pilloff, J. A. Iserte, M. A. Tortorici, B. I. Stephan, M. F. Bilen, P. D. Ghiringhelli, M. E. Lozano, Norbert K. Herzog   +11 more
wiley   +1 more source

Combination of highly antigenic nucleoproteins to inaugurate a cross-reactive next generation vaccine candidate against Arenaviridae family

Heliyon, 2021
Arenaviral infections often result lethal hemorrhagic fevers, affecting primarily in African and South American regions. To date, there is no FDA-approved licensed vaccine against arenaviruses and treatments have been limited to supportive therapy. Hence,
Kazi Faizul Azim, Tahera Lasker, Rahima Akter, Mantasha Mahmud Hia, Omar Faruk Bhuiyan, Mahmudul Hasan, Md Nazmul Hossain   +6 more
doaj   +1 more source

Bioterrorism [PDF]

, 2006
Terrorism preparedness is a highly specific component of general emergency preparedness. In addition to the unique pediatric issues involved in general emergency preparedness, terrorism preparedness must consider several additional issues, including the ...
Markenson, David, Redlener, Irwin E.
core   +2 more sources

Measurement of Antibodies to Machupo Virus by the Indirect Fluorescent Technique

Experimental Biology and Medicine, 1973
Bolivian hemorrhagic fever (BHF) was first recognized in the Province of Beni, Bolivia, in 1959 (1), and cases have continued to occur since then. Recent outbreaks have confirmed the fact that clinical manifestations can be quite nonspecific. Laboratory diagnosis is handicapped by a scarcity of facilities in the endemic region, as well as by the hazard
C J, Peters, P A, Webb, K M, Johnson
openaire   +2 more sources