Results 41 to 50 of about 1,606 (115)
Hematology Reports, 2020 World Health Organization (WHO) declared coronavirus disease (COVID-19) a pandemic in March 2020. Currently almost every country in the world has reported cases with moderate to high mortality rates. The European Union (EU), the United States of America (
Seidu A. Richard +2 more
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Multiplex Degenerate Primer Design for Targeted Whole Genome Amplification of Many Viral Genomes
Advances in Bioinformatics, Volume 2014, Issue 1, 2014., 2014 Background. Targeted enrichment improves coverage of highly mutable viruses at low concentration in complex samples. Degenerate primers that anneal to conserved regions can facilitate amplification of divergent, low concentration variants, even when the strain present is unknown. Results.
Shea N. Gardner +6 more
wiley +1 more source
Family‐Specific Degenerate Primer Design: A Tool to Design Consensus Degenerated Oligonucleotides
Biotechnology Research International, Volume 2013, Issue 1, 2013., 2013 Designing degenerate PCR primers for templates of unknown nucleotide sequence may be a very difficult task. In this paper, we present a new method to design degenerate primers, implemented in family‐specific degenerate primer design (FAS‐DPD) computer software, for which the starting point is a multiple alignment of related amino acids or nucleotide ...
Javier Alonso Iserte +6 more
wiley +1 more source
Urgent pandemic messaging of WHO, World Bank, and G20 is inconsistent with their evidence base
Global Policy, Volume 15, Issue 4, Page 689-707, September 2024.Abstract When international agencies make claims of an “existential threat” to humanity and advocate for urgent action from countries, it should be a safe assumption that they are consistent with their own data. However, a review of the data and evidentiary citations underlying the claims of the World Health Organization (WHO), the World Bank, and the ...
David Bell +3 more
wiley +1 more source
Advances in Virology, Volume 2011, Issue 1, 2011., 2011 Several arenaviruses cause hemorrhagic fever disease in humans and pose a significant public health concern in their endemic regions. On the other hand, the prototypic arenavirus LCMV is a superb workhorse for the investigation of virus‐host interactions and associated disease.
Shuzo Urata +2 more
wiley +1 more source
Expression and Purification of Z Protein from Junín Virus
BioMed Research International, Volume 2010, Issue 1, 2010., 2010 Arenaviridae comprises 23 recognized virus species with a bipartite ssRNA genome and an ambisense coding strategy. The virions are enveloped and include nonequimolar amounts of each genomic RNA species, designated L and S, coding for four ORFs (N, GPC, L, and Z).
S. E. Goñi +11 more
wiley +1 more source
Multifunctional Mobile Module Complex for Analysis of Pathogenic Biological Materials (Agents)
Вестник войск РХБ защиты, 2023 Multifunctional mobile module complex for analysis of pathogenic biological materials (agents) (MKA PBA) and for the support of the decisions of the operational groups of the Ministry of Defence of Russia in case of biological emergencies, has been ...
M. V. Supotnitskiy
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A single mutation (V64G) within the RING Domain of Z attenuates Junin virus.
PLoS Neglected Tropical Diseases, 2020 Junin virus (JUNV) is a New World arenavirus that is the causative agent of Argentine hemorrhagic fever (AHF). Candid#1 (Can) is a live-attenuated vaccine strain of JUNV that since its introduction has resulted in a marked decrease in AHF incidence ...
Steven J Hallam +7 more
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Heliyon, 2021 Arenaviral infections often result lethal hemorrhagic fevers, affecting primarily in African and South American regions. To date, there is no FDA-approved licensed vaccine against arenaviruses and treatments have been limited to supportive therapy. Hence,
Kazi Faizul Azim +6 more
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The Ectodomain of Glycoprotein from the Candid#1 Vaccine Strain of Junin Virus Rendered Machupo Virus Partially Attenuated in Mice Lacking IFN-αβ/γ Receptor. [PDF]
PLoS Neglected Tropical Diseases, 2016 Machupo virus (MACV), a New World arenavirus, is the etiological agent of Bolivian hemorrhagic fever (BHF). Junin virus (JUNV), a close relative, causes Argentine hemorrhagic fever (AHF).
Takaaki Koma +7 more
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