Results 61 to 70 of about 1,606 (115)

Fiebres hemorrágicas por Arenavirus en Latinoamérica

Salud Uninorte, 2010
Las fiebres hemorrágicas virales producidas por Arenavirus incluyen a los virus endémicos en África (Lassa) y el virus de la coriomeningitis linfocítica (LCMV), de distribución mundial, y los Arenavirus del Nuevo Mundo o Complejo Tacaribe, que incluye a ...
Ella Soto, Salim Mattar
doaj  

The Current State of Vaccine Development for Specific Prophylactics of Arenaviral Hemorrhagic Fevers

Проблемы особо опасных инфекций, 2018
Presently, the Arenavirus genus (Arenaviridae family) includes 26 individual species of viruses. It is divided into two main groups – Old World arenaviruses and New World arenaviruses.
T. E. Sizikova, V. N. Lebedev, S. I. Syromyatnikova, S. V. Borisevich   +3 more
doaj   +1 more source

An attenuated Machupo virus with a disrupted L-segment intergenic region protects guinea pigs against lethal Guanarito virus infection

Scientific Reports, 2017
Machupo virus (MACV) is a New World (NW) arenavirus and causative agent of Bolivian hemorrhagic fever (HF). Here, we identified a variant of MACV strain Carvallo termed Car91 that was attenuated in guinea pigs.
Joseph W. Golden, Brett Beitzel, Jason T. Ladner, Eric M. Mucker, Steven A. Kwilas, Gustavo Palacios, Jay W. Hooper   +6 more
doaj   +1 more source

Future Developments and Applications of the Vaccines against Dangerous Viral Infections, RNA-Replicon-Based, Obtained from the Venezuelan Equine Encephalomyelitis Virus

Проблемы особо опасных инфекций, 2014
The members of the Filoviridae (Marburg and Ebola viruses) and Arenaviridae (Lassa, Lujo, Machupo, Junin, Guanarito, Sabia viruses) families are the etiological agents of particularly dangerous viral hemorrhagic fevers.
A. A. Petrov, V. N. Lebedev, T. M. Plekhanova, L. F. Stobva, O. N. Sidorova, E. V. Mel’Nikova, S. V. Borisevich   +6 more
doaj   +1 more source

A multivalent and cross-protective vaccine strategy against arenaviruses associated with human disease.

PLoS Pathogens, 2009
Arenaviruses are the causative pathogens of severe hemorrhagic fever and aseptic meningitis in humans, for which no licensed vaccines are currently available. Pathogen heterogeneity within the Arenaviridae family poses a significant challenge for vaccine
Maya F Kotturi, Jason Botten, John Sidney, Huynh-Hoa Bui, Lori Giancola, Matt Maybeno, Josie Babin, Carla Oseroff, Valerie Pasquetto, Jason A Greenbaum, Bjoern Peters, Joey Ting, Danh Do, Lo Vang, Jeff Alexander, Howard Grey, Michael J Buchmeier, Alessandro Sette   +17 more
doaj   +1 more source

A New Transferrin Receptor Aptamer Inhibits New World Hemorrhagic Fever Mammarenavirus Entry

Molecular Therapy: Nucleic Acids, 2016
Pathogenic New World hemorrhagic fever mammarenaviruses (NWM) utilize Glycoprotein 1 (GP1) to target the apical domain of the human transferrin receptor (hTfR) for facilitating cell entry. However, the conservation between their GP1s is low.
Keith E Maier, Rohit K Jangra, Kevin R Shieh, David K Cureton, Hui Xiao, Erik L Snapp, Sean P Whelan, Kartik Chandran, Matthew Levy   +8 more
doaj   +1 more source

Historical trends demonstrate a pattern of increasingly frequent and severe spillover events of high-consequence zoonotic viruses. [PDF]

BMJ Glob Health, 2023
Meadows AJ, Stephenson N, Madhav NK, Oppenheim B.   +3 more
europepmc   +1 more source

Understanding machupo virus: A neglected arenavirus with global health importance. [PDF]

World J Virol
Uppala PK, Karanam SK, Kandra NV, Edhi S.   +3 more
europepmc   +1 more source

Reemergence of Bolivian Hemorrhagic Fever, 2007–2008

Emerging Infectious Diseases, 2009
Patricia V. Aguilar, Wilfredo Camargo, Jorge Vargas, Carolina Guevara, Yelin Roca, Vidal Felices, Alberto Laguna-Torres, Robert B. Tesh, Thomas G. Ksiazek, Tadeusz J. Kochel   +9 more
doaj   +1 more source

Junín virus and Argentine haemorrhagic fever: Virology, pathogenesis, diagnosis, and prevention strategies. [PDF]

World J Virol
Karanam SK, Uppala PK, Kandra NV, Edhi S.   +3 more
europepmc   +1 more source