Results 31 to 40 of about 1,789,414 (194)
Вестник войск РХБ защиты, 2023 This review is dedicated to the peculiarities of pathogenesis of the experimental Bolivian hemorrhagic fever (BHF) - the disease, caused by Machupo virus (Arenaviridae family).
T. E. Sizikova +4 more
doaj +1 more source
Ribonucleoprotein transport in Negative Strand RNA viruses
Biology of the Cell, Volume 115, Issue 1, January 2023., 2023 The genome replication of Negative‐sense, single‐stranded RNA viruses most‐often segregate in membrane‐less environments called inclusion bodies (IBs). These “organelles” usually locate far from the cell surface from where new virions are released. Here, for each viral family, we discuss how the genome progeny is transported from the IBs to reach the ...
Cédric Diot +2 more
wiley +1 more source
Chapare virus, a newly discovered arenavirus isolated from a fatal hemorrhagic fever case in Bolivia. [PDF]
PLoS Pathogens, 2008 A small focus of hemorrhagic fever (HF) cases occurred near Cochabamba, Bolivia, in December 2003 and January 2004. Specimens were available from only one fatal case, which had a clinical course that included fever, headache, arthralgia, myalgia, and ...
Simon Delgado +11 more
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Recruitment of dynein and kinesin to viral particles
The FASEB Journal, Volume 36, Issue 5, May 2022., 2022 Abstract Dynein and kinesin are cytoskeletal motor proteins involved in transporting cellular cargos and viruses. Throughout viral infection, they actively participate in the virus life cycle in the cell during entry, genome replication, and departure.
Sayi’Mone Tati, Laleh Alisaraie
wiley +1 more source
Observation of arenavirus nucleoprotein heptamer assembly
FEBS Open Bio, Volume 11, Issue 4, Page 1076-1083, April 2021., 2021 The nucleoprotein associates with RNA to form a ribonucleoprotein complex. The nucleoprotein trends to self‐assemble into heptameric rings. Theses rings represent stable intermediate states representative of the average full turn of the Arenaviridae ribonucleoprotein filament.
Nicolas Papageorgiou +6 more
wiley +1 more source
mBio, 2022 Transmission of the New World hemorrhagic fever arenaviruses Junín virus (JUNV) and Machupo virus (MACV) to humans is facilitated, in part, by the interaction between the arenavirus GP1 glycoprotein and the human transferrin receptor 1 (hTfR1).
Weng M. Ng +9 more
doaj +1 more source
Application of spectral library prediction for parallel reaction monitoring of viral peptides
PROTEOMICS, Volume 21, Issue 7-8, April 2021., 2021 Abstract A major part of the analysis of parallel reaction monitoring (PRM) data is the comparison of observed fragment ion intensities to a library spectrum. Classically, these libraries are generated by data‐dependent acquisition (DDA). Here, we test Prosit, a published deep neural network algorithm, for its applicability in predicting spectral ...
Marica Grossegesse +3 more
wiley +1 more source
Frontiers in Microbiology, 2021 Ebola virus infection causes severe hemorrhagic fever, and its mortality rates varied from 25 to 90% in the previous outbreaks. The highly infectious and lethal nature of this virus highlights the need for reliable and sensitive diagnostic methods to ...
Wenwu Yao +5 more
doaj +1 more source
PLoS Pathogens, 2021 Signal-regulatory protein alpha (SIRPA) is a well-known inhibitor of phagocytosis when it complexes with CD47 expressed on target cells. Here we show that SIRPA decreased in vitro infection by a number of pathogenic viruses, including New World and Old ...
Nicolás Sarute +6 more
doaj +1 more source
Rescue of a recombinant Machupo virus from cloned cDNAs and in vivo characterization in interferon (αβ/γ) receptor double knockout mice. [PDF]
J Virol, 2014 Patterson M +12 more
europepmc +2 more sources