VIPR: a probabilistic algorithm for analysis of microbial detection microarrays [PDF]
, 2010 Background All infectious disease oriented clinical diagnostic assays in use today focus on detecting the presence of a single, well defined target agent or a set of agents.
Adam F Allred +6 more
core +2 more sources
The Current State of Vaccine Development for Specific Prophylactics of Arenaviral Hemorrhagic Fevers
Проблемы особо опасных инфекций, 2018 Presently, the Arenavirus genus (Arenaviridae family) includes 26 individual species of viruses. It is divided into two main groups – Old World arenaviruses and New World arenaviruses.
T. E. Sizikova +3 more
doaj +1 more source
Absence of an N-Linked Glycosylation Motif in the Glycoprotein of the Live-Attenuated Argentine Hemorrhagic Fever Vaccine, Candid #1, Results in Its Improper Processing, and Reduced Surface Expression [PDF]
, 2017 Junin virus (JUNV), a highly pathogenic New World arenavirus, is the causative agent of Argentine hemorrhagic fever (AHF). The live-attenuated Candid #1 (Can) strain currently serves as a vaccine for at-risk populations. We have previously shown that the
Alexey V. Seregin +7 more
core +1 more source
DNAZYMES AS A METHOD FOR NIPAH HENIPAVIRUS DETECTION
International Journal of Infectious Diseases, 2023 Intro: Deoxyribozymes (Dz) are short synthetic DNA oligonucleotides that catalyze the cleavage of a phosphodiester bond between nucleotides in the presence of divalent metal ions.
A. Kirichenko +4 more
doaj +1 more source
Modelling the severe acute respiratory syndrome epidemic [3] [PDF]
, 2003 published_or_final_versio
Chau, PH, Yip, PSF
core
The Protein Kinase Receptor Modulates the Innate Immune Response against Tacaribe Virus
Viruses, 2021 The New World (NW) mammarenavirus group includes several zoonotic highly pathogenic viruses, such as Junin (JUNV) or Machupo (MACV). Contrary to the Old World mammarenavirus group, these viruses are not able to completely suppress the innate immune ...
Hector Moreno, Stefan Kunz
doaj +1 more source
Japanese encephalitis virus counteracts BST2 restriction via its envelope protein E. [PDF]
, 2017 It has been well documented that BST2 restricts the release of enveloped viruses by cross-linking newly produced virions to the cell membrane. However, it is less clear whether and how BST2 inhibits the release of enveloped viruses which bud via the ...
Fu, M +11 more
core +1 more source
Lassa fever. Part 1. Etiology, epidemiology and clinical manifestations
Инфекция и иммунитет, 2022 Lassa fever is a natural focal disease dangerous for humans. In the larger part of sub-Saharan West Africa 37.7 million people in 14 countries live in areas where living conditions are suitable for zoonotic transmission of the virus from secretions of ...
Elena I. Kazachinskaia +3 more
doaj +1 more source
Targeting of arenavirus RNA synthesis by a carboxamide-derivatized aromatic disulfide with virucidal activity. [PDF]
, 2013 Several arenaviruses can cause severe hemorrhagic fever (HF) in humans, representing a public health threat in endemic areas of Africa and South America.
Damonte, Elsa Beatriz +4 more
core +2 more sources
TIM-family Proteins Promote Infection of Multiple Enveloped Viruses through Virion-associated Phosphatidylserine [PDF]
, 2013 Human T-cell Immunoglobulin and Mucin-domain containing proteins (TIM1, 3, and 4) specifically bind phosphatidylserine (PS). TIM1 has been proposed to serve as a cellular receptor for hepatitis A virus and Ebola virus and as an entry factor for dengue ...
Ahmed, Asim Aminsharif +11 more
core +7 more sources