Results 111 to 120 of about 29,619 (221)

Role of mucosal-associated invariant T cells dynamics in pathogenesis of Sjögren syndrome

Scientific Reports
Sjögren syndrome (SS) is an autoimmune disease characterized by chronic inflammatory infiltrates in the salivary and lacrimal glands. Mucosal-associated invariant T (MAIT) cells are a subset of innate-like T-cells, predominantly found in mucosal tissues ...
Jeanne Chauffier, Henri Berger de Gallardo, Mathieu F. Chevalier, Aïcha Kante, Marion Lambert, Xavier Cabrol, Elisa Aldersons, Stéphane Mouly, Karine Champion, Blanca Amador-Borrero, Ruxandra Burlacu, William Bigot, Homa Adle-Biassete, Rachid Kaci, Aurélie Selvanadin, Martine Cohen-Solal, Amélie Coudert, Sophie Caillat-Zucman, Damien Sène, Cloé Comarmond   +19 more
doaj   +1 more source

Arming of MAIT Cell Cytolytic Antimicrobial Activity Is Induced by IL-7 and Defective in HIV-1 Infection.

PLoS Pathogens, 2015
Mucosa-associated invariant T (MAIT) cells represent a large innate-like evolutionarily conserved antimicrobial T-cell subset in humans. MAIT cells recognize microbial riboflavin metabolites from a range of microbes presented by MR1 molecules. MAIT cells
Edwin Leeansyah, Jenny Svärd, Joana Dias, Marcus Buggert, Jessica Nyström, Máire F Quigley, Markus Moll, Anders Sönnerborg, Piotr Nowak, Johan K Sandberg   +9 more
doaj   +1 more source

Mucosal-associated invariant T cells in cancer: dual roles, complex interactions and therapeutic potential

Frontiers in Immunology
Mucosal-associated invariant T (MAIT) cells play diverse roles in cancer, infectious diseases, and immunotherapy. This review explores their intricate involvement in cancer, from early detection to their dual functions in promoting inflammation and ...
Mesut Yigit, Omer Faruk Basoglu, Derya Unutmaz   +2 more
doaj   +1 more source

Estrogen Induced Regulation of Mucosal-Associated Invariant T Cells in Asthma

Journal of Immunology Research
Asthma affects over 300 million people worldwide, with increasing rates annually. Males have higher asthma prevalence in adolescence, while females exhibit higher rates in adulthood. Reduced mucosal-associated invariant T (MAIT) cells are found in severe
Shubhanshi Trivedi, Samuel E. Aamodt, Thomas P. Huecksteadt, Elizabeth J. Myers, Grace Helen McGee, Jackson G. Cacioppo, Jeffrey Aubé, Robert Paine, Daniel T. Leung, Kristi J. Warren   +9 more
doaj   +1 more source

Immune checkpoint blockade improves the activation and function of circulating mucosal-associated invariant T (MAIT) cells in patients with non-small cell lung cancer

OncoImmunology
Mucosal-associated invariant T (MAIT) cells constitute one of the most numerous unconventional T cell subsets, and are characterized by rapid release of Th1- and Th17-associated cytokines and increased cytotoxic functions following activation. MAIT cells
Patrik Sundström, Nikita Dutta, William Rodin, Andreas Hallqvist, Sukanya Raghavan, Marianne Quiding Järbrink   +5 more
doaj   +1 more source

Maite Ezcurdia

Análisis Filosófico, 2019
Eleonora Orlando, Diana Perez
openaire   +2 more sources

CXCR6-positive circulating mucosal-associated invariant T cells can identify patients with non-small cell lung cancer responding to anti-PD-1 immunotherapy

Journal of Experimental & Clinical Cancer Research
Background Mucosal-associated invariant T (MAIT) cells have been reported to regulate tumor immunity. However, the immune characteristics of MAIT cells in non-small cell lung cancer (NSCLC) and their correlation with the treatment efficacy of immune ...
Jingjing Qu, Binggen Wu, Lijun Chen, Zuoshi Wen, Liangjie Fang, Jing Zheng, Qian Shen, Jianfu Heng, Jianya Zhou, Jianying Zhou   +9 more
doaj   +1 more source

Optimization of armored spherical tanks for storage on the lunar surface [PDF]

A redundancy strategy for reducing micrometeroid armoring mass is investigated, with application to cryogenic reactant storage for a regenerative fuel cell (RFC) on the lunar surface.
Bents, D. J., Knight, D. A.
core   +1 more source

Mucosal-Associated Invariant T (MAIT) cells are impaired in Th17 associated primary and secondary immunodeficiencies

The recently described Mucosal Associated Invariant T (MAIT) cells mediate specific recognition of bacterial and fungal vitamin B2 metabolites. As innate T cells, they possess broad effector responses, including IFN- including Iproduction, that are ...
Barcenas-Morales, Gabriela, Döffinger, Rainer, Eren, Efrem, Faust, Saul N., Gao, Yifang, Ottensmeier, Christian H., Rae, William, Ramakrishnan, Keseva, Williams, Anthony P.   +8 more
core   +1 more source

ON THE PRICE OF RECREATION GOODS AS A DETERMINANT OF MALE LABOR SUPPLY [PDF]

This paper examines whether and how changes in the price of goods consumed in conjunction with leisure time influence the life-cycle allocation of work effort by part of prime-age males.
Jorge González-Chapela
core