Results 111 to 120 of about 4,910,474 (212)

Mucosal Associated Invariant T cells in the human gastric mucosa and blood: Role in Helicobacter pylori infection

Frontiers in Immunology, 2015
Mucosal-associated invariant T (MAIT) cells represent a class of antimicrobial innate-like T cells that have been characterized in human blood, liver, lungs and intestine.
Jayaum S Booth, Jayaum S Booth, Rosangela eSalerno-Goncalves, Rosangela eSalerno-Goncalves, Thomas G Blanchard, Seema A. Patil, Seema A. Patil, Howard A. Kader, Anca M. Safta, Lindsay M. Morningstar, Steven J. Czinn, Bruce D. Greenwald, Bruce D. Greenwald, Marcelo B. Sztein, Marcelo B. Sztein, Marcelo B. Sztein   +15 more
doaj   +1 more source

Mucosal-associated invariant T (MAIT) cell contributions to mucosal immunity

, 2016
Thesis (Ph.D.)--University of Washington, 2016-10Mucosal-associated invariant T (MAIT) cells are a semi-invariant T cell subset that are located in blood, liver and mucosal tissues.
Slichter, Chloe Knights
core  

MAIT Cells with High PFN1 Expression Mediate Immune Activation and Metabolic Reprogramming in Psoriasis [PDF]

Man-Ning Wu,1– 3 Yue-Min Zou,1– 3 Xiang-Nan Zhou,2,3 Sangwon Hong,1– 3 Lei Wang,2,3 Yan-Ping Bai2,3 1Beijing University of Chinese Medicine, Beijing, 100029, People’s Republic of China; 2Department of Dermatology, China-Japan Friendship Hospital ...
Zou YM, Zhou XN, Bai YP, Wu MN, Hong S, Wang L   +5 more
core  

Aberrant MAIT cell transcription factor expression in chronic HIV-1 infection correlates with MAIT cell effector dysfunction.

, 2015
(A) Unstimulated PBMCs from 10 healthy controls and 17 HIV-1 infected, ART-untreated patients were stained for transcription factors, and their MAIT cell T-bet and Eomes expression profile was determined.
Joana Dias (786016), Jessica Nyström (277460), Markus Moll (109640), Edwin Leeansyah (366399), Marcus Buggert (153550), Máire F. Quigley (786017), Piotr Nowak (277458), Jenny Svärd (786015), Johan K. Sandberg (353026), Anders Sönnerborg (153581)   +9 more
core   +1 more source

Study of MAIT cell activation in viral infections in vivo [PDF]

, 2019
MAIT cells are abundant, highly evolutionarily conserved innate-like lymphocytes expressing a semi-invariant T cell receptor (TCR), which recognizes microbially derived small intermediate molecules from the riboflavin biosynthetic pathway.
Chen, Z, van Wilgenburg, Bonnie, Huimeng Wang, Alexandra J. Corbett, Wang, Huimeng, Koutsakos, M, Zhenjun Chen, Loh, Liyen, van Wilgenburg, B, Koutsakos, Marios, Loh, L, Wang, H, Katherine Kedzierska, Hinks, TSC, Corbett, AJ, Kedzierska, Katherine, Corbett, Alexandra J, Chen, Zhenjun, Hinks, Timothy SC, Timothy S. C. Hinks, Bonnie van Wilgenburg, Kedzierska, K, Liyen Loh, Marios Koutsakos   +23 more
core   +1 more source

A shotgun proteomic dataset of human mucosal-associated invariant T cells

Data in Brief
Mucosal-associated invariant T (MAIT) cells represent a unique unconventional T cell population important in eliciting immunomodulatory responses in a range of diseases, including infectious diseases, autoimmunity and cancer.
Harshi Weerakoon, John J. Miles, Michelle M. Hill, Ailin Lepletier   +3 more
doaj   +1 more source

Functions of mucosal associated invariant T cells in eye diseases

Frontiers in Immunology
Mucosal-associated invariant T (MAIT) cells are a unique subset of T cells that recognizes metabolites derived from the vitamin B2 biosynthetic pathway. Since the identification of cognate antigens for MAIT cells, knowledge of the functions of MAIT cells
Chihiro Fukui, Satoshi Yamana, Yanqi Xue, Mariko Shirane, Hiroki Tsutsui, Kenichiro Asahara, Keiko Yoshitomi, Takako Ito, Tantri Lestari, Eiichi Hasegawa, Nobuyo Yawata, Atsunobu Takeda, Koh-Hei Sonoda, Kensuke Shibata, Kensuke Shibata, Kensuke Shibata   +15 more
doaj   +1 more source

MAIT cell responses to Staphylococcus aureus and sensitivity to HlgAB toxin are modulated by activation and tissue-dependent virulence effects

mBio
Mucosa-associated invariant T (MAIT) cells are unconventional T cells with innate-like rapid antimicrobial effector functions and serve as resident sentinels at mucosal and non-mucosal barriers.
Elisa J. M. Raineri, Caroline Boulouis, Elli Mouchtaridi, Vera Nilsén, Curtis Cai, Tobias Kammann, Juliette Tabusse, Takuya Sekine, Nicole Wild, Christian Constantz, Eoghann White, Thomas R. Müller, Anne Marchalot, Sabrina Ferreira, Jyotsana Kaushal, Akhirunnesa Mily, Miriam Franklin, Elena Bonaiti, Mary-Lyn Eichhorn, John Bassett, Chris Stamper, Jeffrey Y. W. Mak, David P. Fairlie, Chris Tibbitt, Anna Norrby-Teglund, Nicole Marquardt, Jenny Mjösberg, Carl Jorns, Jenny Driving, Edwin Leeansyah, Marcus Buggert, Johan K. Sandberg   +31 more
doaj   +1 more source

IL-7 restores MAIT cell effector dysfunction.

, 2015
(A) MAIT cell arming following IL-7 treatment in vitro for 48 h in healthy controls (n = 8), and HIV-1 infected ART-untreated patients (n = 6). GrzA and Prf upregulation was determined as fold-change of geometric MFI to that of IL-7-untreated cells ...
Joana Dias (786016), Jessica Nyström (277460), Markus Moll (109640), Edwin Leeansyah (366399), Marcus Buggert (153550), Máire F. Quigley (786017), Piotr Nowak (277458), Jenny Svärd (786015), Johan K. Sandberg (353026), Anders Sönnerborg (153581)   +9 more
core   +1 more source

Diagnostic accuracy of interferon-gamma release assay and mucosal-associated invariant T cells in spinal tuberculosis

Scientific Reports
Conventional diagnostic methods for tuberculous spondylodiscitis (TS) require tissue biopsy, which can delay diagnosis. Immunodiagnostic approaches, including interferon-gamma release assays (IGRAs), have shown potential for improving TS diagnosis ...
Korawish Mekariya, Pisanukiet Saneewong Na Ayutthaya, Akkaraporn Naowanirut, Artit Wongsa, Boonrat Tassaneetrithep, Wiwit Tantibhedhyangkul, Popchai Ngamskulrungroj, Sorranart Muangsomboon, Pipat Cheiwvit, Sirichai Wilartratsami, Panya Luksanapruksa, Nasuda Danchaivijitr, Kitidete Boonchai, Apisit Rattanatanasarn, Monchai Ruangchainikom   +14 more
doaj   +1 more source