Results 71 to 80 of about 12,026,666 (219)

Number of colonic MAIT cell TCRB sequences found, and their overlap with blood MAIT cells.

, 2023
Number of colonic MAIT cell TCRB sequences found, and their overlap with blood MAIT cells.
Donna M. Shows (17334267), James D. Lord (17334270), Andrew J. Konecny (17334264)   +2 more
core   +1 more source

Biological functions of MAIT cells in tissues

Molecular Immunology, 2021
Mucosal associated invariant T (MAIT) cells have a recognised innate-like capacity for antibacterial host defence, consequent on the specificity of their T cell receptor (TCR) for small molecule metabolites produced by a range of prokaryotic and fungal species, their effector memory phenotype, and their expression of cytotoxic molecules.
Klenerman, Paul, Hinks, Timothy S.C., Ussher, James E.   +2 more
openaire   +2 more sources

Mucosal-Associated Invariant T Cells Display Diminished Effector Capacity in Oesophageal Adenocarcinoma

Frontiers in Immunology, 2019
Oesophageal adenocarcinoma (OAC) is an aggressive malignancy with poor prognosis, and incidence is increasing rapidly in the Western world. Mucosal-associated invariant T (MAIT) cells recognize bacterial metabolites and kill infected cells, yet their ...
Ashanty M. Melo, Aisling M. O'Brien, James J. Phelan, Susan A. Kennedy, Nicole A. W. Wood, Natacha Veerapen, Gurdyal S. Besra, Niamh E. Clarke, Emma K. Foley, Akshaya Ravi, Finbar MacCarthy, Dermot O'Toole, Narayamasami Ravi, Narayamasami Ravi, John V. Reynolds, John V. Reynolds, Melissa J. Conroy, Andrew E. Hogan, Andrew E. Hogan, Jacintha O'Sullivan, Margaret R. Dunne   +20 more
doaj   +1 more source

Mucosal-Associated Invariant T Cell Response to Acute Exercise and Exercise Training in Older Obese Women

Sports, 2021
(1) Background: Obesity is a major global public health concern as it is associated with many of the leading causes of preventable deaths. Exercise reduces obesity-induced inflammation; however, it is unknown how exercise training may impact mucosal ...
Lauren C. Bates, Erik D. Hanson, Michael M. Levitt, Bryan Richie, Elise Erickson, David B. Bartlett, Melody D. Phillips   +6 more
doaj   +1 more source

Mucosal-associated invariant T (MAIT) cells produce growth factors and influence the regeneration of hepatic spheroids [PDF]

, 2022
openContesto: Il fegato è un importante sito immunologico che riceve prodotti batterici, tossine e antigeni di varia natura dal tratto gastrointestinale. Per operare una difesa efficace si basa principalmente su un solido sistema immunitario innato e il
TASIN, IRENE
core  

MAIT cell activation and dynamics associated with COVID-19 disease severity

Science immunology, 2020
MAIT cell activation and decline in blood are associated with COVID-19 severity, features that dynamically recover in convalescence. Severe COVID-19 is characterized by excessive inflammation of the lower airways.
Tiphaine Parrot, J. Gorin, A. Ponzetta, Kimia T. Maleki, Tobias Kammann, Johanna E. M. Emgård, André Perez-Potti, T. Sekine, Olga Rivera-Ballesteros, E. Folkesson, O. Rooyackers, L. Eriksson, A. Norrby-Teglund, H. Ljunggren, N. Björkström, S. Aleman, M. Buggert, J. Klingström, K. Strålin, J. Sandberg   +19 more
semanticscholar   +1 more source

MAIT cell compartment characteristics are associated with the immune response magnitude to the BNT162b2 mRNA anti-SARS-CoV-2 vaccine

Molecular Medicine, 2022
Mucosa-associated invariant T (MAIT) cells are unconventional T cells with innate-like capacity to rapidly respond to microbial infection via MR1-restricted antigen recognition.
Caroline Boulouis, Tobias Kammann, Angélica Cuapio, Tiphaine Parrot, Yu Gao, Elli Mouchtaridi, David Wullimann, J. Lange, Puran Chen, Mira Akber, Olga Rivera Ballesteros, J. R. Muvva, Margaret Katie Michal Gunnar Ola Anders Stephan Lotta Per A Sällberg Chen Healy Sobkowiak Söderdahl Blennow Ös, Margaret Sällberg Chen, K. Healy, M. Sobkowiak, Gunnar Söderdahl, O. Blennow, Anders Österborg, Stephan Mielke, L. Hansson, P. Ljungman, A. Norlin, Emilie Wahren-Borgström, G. Bogdanovic, S. Muschiol, Fredrika Hellgren, K. Loré, C. I. Smith, J. Vesterbacka, O. Kieri, P. Nowak, P. Bergman, M. Buggert, H. Ljunggren, S. Aleman, J. Sandberg   +36 more
semanticscholar   +1 more source

Isolation and Characterization of MAIT Cells from Tumor Tissues

, 2019
Mucosal-associated invariant T (MAIT) cell infiltration has been demonstrated in colorectal and hepatocellular carcinoma, and their ability to produce Th1- and Th17-associated cytokines, as well as their cytotoxic function, suggests that MAIT cells may ...
Quiding-Järbrink, Marianne,, William Rodin, Sundström, Patrik,, Patrik Sundström, Marianne Quiding Järbrink, Rodin, William,   +5 more
core   +1 more source

MAIT cells in autoimmunity

Japanese Journal of Clinical Immunology, 2012
Mucosal associated invariant T (MAIT) cells are restricted by a nonpolymorphic MHC-related molecule-1 (MR1), and express an invariant TCRα chain: Vα7.2-Jα33 in humans and Vα19-Jα33 in mice. MAIT cells are selected in the thymus, but, interestingly, MAIT cells require B cells as well as commensal flora for their peripheral expansion.
openaire   +5 more sources

Classic Costimulatory Interactions in MAIT Cell Responses: From Gene Expression to Immune Regulation.

Clinical and Experimental Immunology, 2023
Mucosa-associated invariant T (MAIT) cells are evolutionarily conserved, innate-like T lymphocytes with enormous immunomodulatory potentials.
Nicole I. Wang, M. Ninkov, S. M. Haeryfar   +2 more
semanticscholar   +1 more source