Results 111 to 120 of about 78,708 (218)
The use of transgenic parasites in malaria vaccine research
Expert Review of Vaccines, 2017 Introduction: Transgenic malaria parasites expressing foreign genes, for example fluorescent and luminescent proteins, are used extensively to interrogate parasite biology and host-parasite interactions associated with malaria pathology.
Ahmad Syibli Othman +5 more
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Routine malaria vaccination in Africa: a step toward malaria eradication?
Malaria JournalMalaria remains a significant global health challenge, with nearly half of the world's population at risk of infection. In 2022 alone, malaria claimed approximately 608,000 lives, with 76% of these fatalities occurring in children under the age of five ...
Olivier Sibomana +9 more
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Recent advances on vaccines against malaria: A review
Asian Pacific Journal of Tropical MedicineThis review aims to summarize the currently viable vaccine strategies including the approved vaccines and the those in trials for next-generation malaria vaccines. Data on malaria vaccine development was collected through a comprehensive review.
Shiza Malik, Yasir Waheed
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PLoS ONE, 2019 The development of effective malaria vaccines remains a global health priority. Currently, the most advanced vaccine, known as RTS,S, has only shown modest efficacy in clinical trials.
Jo-Anne Chan +14 more
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Human Vaccines & Immunotherapeutics, 2017 Although vaccines would be the ideal tool for control, prevention, elimination, and eradication of many infectious diseases, developing of parasites vaccines such as malaria vaccine is very complex.
Shima Mahmoudi, Hossein Keshavarz
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Wise Blood: The Principle of Overcoming in Disease and Immunity (Part 1) [PDF]
, 2020 The immune system is an intelligently made system designed for interaction with microbes even in a perfect world; it is more than a defense. However, in a post-fall world, it is primarily a body’s defense system.
Gillen, Alan L., Huy, Keoprommony
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Indian journal of pathology & microbiology, 1997 Recently it has become evident that he same candidate antigen can be shared by several of the parasite stages, and thus the concept of a multistage vaccine is becoming more and more attractive. A TDR Task Force evaluated the promise and stage of development of some 20 existing asexual blood stage candidate antigens and prepared a strategy for their ...
S K, Khurana, V H, Talib
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A new malaria vaccination tool based on replication-competent Plasmodium falciparum parasites
EMBO Molecular MedicineRecently licensed subunit vaccines represent the first and, thus far, the only approved agents for vaccination against malaria. However, these vaccines still fail to confer highly effective long-lasting protective immunity.
Diana Moita, Miguel Prudêncio
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Conducting Controlled human infection model studies in India is an ethical obligation [PDF]
, 2018 Weighing competing obligations and achieving the “greatest balance” of right over wrong guides an individual, an agency or a country in determining what ought to be done in an ethically challenging situation.
Dholakia, S. Y., Dholakia, Saumil
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Global Public Goods and Global Health [PDF]
, 2012 The repair rate on electron beam welded diaphragm hasn’t been at the desired level at Siemens SIT for several years. An improvement program the past five years has reduce the repair rate from 60% to 12-15% but the goal of 5% repair rate hasn’t been met ...
Gartner, David
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