Autoreactivity to malondialdehyde-modifications in rheumatoid arthritis is linked to disease activity and synovial pathogenesis [PDF]
J Autoimmun. 2017 Nov; 84:29-45, 2017 Oxidation-associated malondialdehyde (MDA) modification of proteins can generate immunogenic neo-epitopes that are recognized by autoantibodies. In health, IgM antibodies to MDA-adducts are part of the natural antibody pool, while elevated levels of IgG anti-MDA are associated with inflammatory conditions.
arxiv +1 more source
Terahertz radiation by optical rectification in a hydrogen-bonded organic molecular ferroelectric crystal, 2-phenylmalondialdehyde [PDF]
Jpn. J. Appl. Phys. 53, 09PD07 (2014); Special issue on
"Ferroelectric Materials and Their Applications", 2014 Terahertz radiation by optical rectification has been observed at room temperature in a hydrogen-bonded organic molecular ferroelectric crystal, 2-phenyl malondialdehyde (PhMDA). The radiated electromagnetic wave consisted of a single-cycle terahertz pulse with a temporal width of $\sim$ 0.5 ps.
arxiv +1 more source
Biochemically altered human erythrocytes as a carrier for targeted delivery of primaquine: an in vitro study [PDF]
Arch. Pharm. Res. (2011) 34: 563, 2019 The aim of this study was to investigate human erythrocytes as a carrier for targeted drug delivery of primaquine (PQ). The process of PQ loading in human erythrocytes, as well as the effect of PQ loading on the oxidative status of erythrocytes, was also studied.
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Scanning Electron Microscopy and Metabolite Measurement Revealed the Stress Mechanism of PS-COOH Microplastics on Rhodotorula mucilaginosa AN5 [PDF]
arXiv, 2022 Microplastics in the marine environment have been paid more and more attention by researchers, and the impact of these substances on marine microorganisms can not be ignored. Studies have shown that PS-COOH Microplastics are harmful to marine molluscs, algae and monads.
arxiv
Depressed serum IgM levels in SLE are restricted to defined subgroups [PDF]
, 2017 Natural IgM autoantibodies have been proposed to convey protection from autoimmune pathogenesis. Herein, we investigated the IgM responses in 396 systemic lupus erythematosus (SLE) patients, divided into subgroups based on distinct autoantibody profiles. Depressed IgM levels were more common in SLE than in matched population controls.
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Digital Quantum Simulation of Laser-Pulse Induced Tunneling Mechanism in Chemical Isomerization Reaction [PDF]
arXiv, 2018 Using quantum computers to simulate polyatomic reaction dynamics has an exponential advantage in the amount of resources needed over classical computers. Here we demonstrate an exact simulation of the dynamics of the laser-driven isomerization reaction of asymmetric malondialdehydes.
arxiv
Delayed treatment with nimesulide reduces measures of oxidative stress following global ischemic brain injury in gerbils [PDF]
Neuroscience Research 47(2): 245-253 (2003), 2007 Metabolism of arachidonic acid by cyclooxygenase is one of the primary sources of reactive oxygen species in the ischemic brain. Neuronal overexpression of cyclooxygenase-2 has recently been shown to contribute to neurodegeneration following ischemic injury.
arxiv
Efficacy of Put and Spd sprayed on leaves from Brassica juncea plants against Cd2+-induced oxidative stress [PDF]
arXiv, 2008 The protective effect exerted by polyamines (Put and Spd) against cadmium (Cd) stress was investigated in Brassica juncea plants. Treatment with CdCl2 (75 micro-Mole) resulted in a rise of Cd accumulation, a decrease of fresh and dry weights in every plant organ, an increase of free polyamine content at limb and stem levels as well as a decrease at ...
arxiv