Results 171 to 180 of about 13,001 (185)

Treatment of highly virulent mammarenavirus infections—status quo and future directions

Expert Opinion on Drug Discovery
Mammarenaviruses are negative-sense bisegmented enveloped RNA viruses that are endemic in Africa, the Americas, and Europe. Several are highly virulent, causing acute human diseases associated with high case fatality rates, and are considered to be significant with respect to public health impact or bioterrorism threat.This review summarizes the status
Ivette Ariela Nunez, Anya Crane, Ian Crozier   +2 more
exaly   +3 more sources

Computer-aided rational design of a mRNA vaccine against Guanarito mammarenavirus

Biotechnology Letters
Guanarito mammarenavirus (GTOV) is a highly pathogenic virus that leads to Venezuelan hemorrhagic fever (VHF). Despite being a severe disease, there are currently no commercially available drugs or vaccines for its prevention.Here we computationally formulated a mRNA vaccine construct (VC) from the genome of GTOV to produce immunity against its ...
Mohibullah Shah, Asifa Sarfraz, Muhammad Shehroz, Asia Perveen, Samavia Jaan, Aqal Zaman, Umar Nishan, Arlindo A. Moura, Riaz Ullah, Zafar Iqbal, Mohamed A. Ibrahim   +10 more
openaire   +2 more sources

A Mammarenavirus Close to Lassa Virus in a Patient with Meningoencephalitis

New England Journal of Medicine
Sylvain Baize, Delphine Pannetier, Christophe Rodriguez, Laurence Josset, Franck de Laval, Bernadette Gergonne, Jean-Baptiste Mardon, Caroline Picard, Alexandra Journeaux, Damien Thomas, Elodie Moissonnier, Céline Ragot, Thibault Martinez, Estelle Lara, Anne-Laure Favier, Olivier Ferraris, Magali Billhot, Mathieu Cabon   +17 more
exaly   +2 more sources

Peptide based vaccine designing against endemic causing mammarenavirus using reverse vaccinology approach

Archives of Microbiology
The rodent-borne Arenavirus in humans has led to the emergence of regional endemic situations and has deeply emerged into pandemic-causing viruses. Arenavirus have a bisegmented ambisense RNA that produces four proteins: glycoprotein, nucleocapsid, RdRp and Z protein.
Dwaipayan, Chaudhuri, Joyeeta, Datta, Satyabrata, Majumder, Kalyan, Giri   +3 more
openaire   +2 more sources

Immunoinformatics analysis to design novel epitope based vaccine candidate targeting the glycoprotein and nucleoprotein of Lassa mammarenavirus (LASMV) using strains from Nigeria

Journal of Biomolecular Structure and Dynamics, 2022
Ohilebo Abdulateef Abass, Vladimir I Timofeev, Bishajit Sarkar   +2 more
exaly  

Chaperonin TRiC/CCT Participates in Mammarenavirus Multiplication in Human Cells via Interaction with the Viral Nucleoprotein

Journal of Virology, 2023
Haydar Witwit, Beatrice Cubitt, Juan Carlos de la Torre   +2 more
exaly  

The ReFRAME library as a comprehensive drug repurposing library to identify mammarenavirus inhibitors

Antiviral Research, 2019
Yu-Jin Kim, Beatrice Cubitt, Arnab K Chatterjee   +2 more
exaly  

One new species in the genus Mammarenavirus

2017
Jin, Qi, Zhiqiang Wu, Yang, Li, Du, Jiang, Buchmeier, Michael J., Charrel, Rémi, Clegg, Christopher S., Torre, Juan Carlos De La, DeRisi, Joseph L., Emonet, Sébastien, Gonzalez, Jean-Paul, Kuhn, Jens H., Lukashevich, Igor S., Peters, Clarence J., Sheli R. Radoshitzky, Romanowski, Victor, Salvato, Maria S., Stenglein, Mark D.   +17 more
openaire   +1 more source

Create one new species in genus Mammarenavirus (Bunyavirales: Arenaviridae)

2020
Z.-L. Shi, Kuhn, Jens H., Lukashevich, Igor S, J. Christopher S. Clegg, Gonzalez, Jean-Paul, Torre, Juan Carlos De La, Hepojoki, Jussi, Salvato, Maria, Stenglein, Mark, Buchmeier, Michael J, Charrel, Remi, Sheli Radoshitzky, Günther, Stephan, Romanowski, Victor, Lamballerie, Xavier De, Sironi, Manuela, B. Agwanda   +16 more
openaire   +1 more source

One (1) new species in the genus Mammarenavirus (Arenaviridae)

2018
Jorlan Fernandes, Guterres, Alexandro, Oliveira, Renata C, Chamberlain, John, Hewson, Roger, Elba R S Lemos   +5 more
openaire   +1 more source