Results 11 to 20 of about 2,479,436 (371)

Evolution of an expanded mannose receptor gene family. [PDF]

open access: goldPLoS ONE, 2014
Sequences of peptides from a protein specifically immunoprecipitated by an antibody, KUL01, that recognises chicken macrophages, identified a homologue of the mammalian mannose receptor, MRC1, which we called MRC1L-B.
Karen Staines   +3 more
doaj   +6 more sources

The Mannose Receptor: From Endocytic Receptor and Biomarker to Regulator of (Meta)Inflammation [PDF]

open access: yesFrontiers in Immunology, 2021
The mannose receptor is a member of the C-type lectin (CLEC) family, which can bind and internalize a variety of endogenous and pathogen-associated ligands.
Hendrik J. P. van der Zande   +4 more
doaj   +3 more sources

Mannose Ligands for Mannose Receptor Targeting. [PDF]

open access: yesInt J Mol Sci
The mannose receptor (MR, CD 206) is an endocytic receptor primarily expressed by macrophages and dendritic cells, which plays a critical role in both endocytosis and antigen processing and presentation. MR carbohydrate recognition domains (CRDs) exhibit a high binding affinity for branched and linear oligosaccharides.
Paurević M   +2 more
europepmc   +4 more sources

Mannose receptor is an HIV restriction factor counteracted by Vpr in macrophages [PDF]

open access: yeseLife, 2020
HIV-1 Vpr is necessary for maximal HIV infection and spread in macrophages. Evolutionary conservation of Vpr suggests an important yet poorly understood role for macrophages in HIV pathogenesis.
Jay Lubow   +11 more
doaj   +3 more sources

Structural analysis of carbohydrate binding by the macrophage mannose receptor CD206. [PDF]

open access: goldJ Biol Chem, 2021
Feinberg H   +6 more
europepmc   +4 more sources

Soluble mannose receptor induces proinflammatory macrophage activation and metaflammation. [PDF]

open access: yesProc Natl Acad Sci U S A, 2021
Significance Obesity-associated metaflammation is an emerging disease, in which proinflammatory macrophages play a decisive role. Here, we identified the soluble mannose receptor (sMR) as a regulator of metaflammation and demonstrated increased levels of
Embgenbroich M   +21 more
europepmc   +2 more sources

Diagnostic value of monocyte chemoattractant Protein-1, soluble mannose receptor, Presepsin, and Procalcitonin in critically ill children admitted with suspected sepsis [PDF]

open access: goldBMC Pediatrics, 2021
Introduction The differentiation between systemic inflammatory response syndrome and sepsis is very important as it determines essential treatment decisions, such as selection, initiation, and duration of antibiotic therapy.
Noha A. Hassuna   +7 more
doaj   +2 more sources

Macrophage mannose receptor, CD206, predict prognosis in patients with pulmonary tuberculosis [PDF]

open access: goldScientific Reports, 2018
Tuberculosis (TB) remains a leading cause of fatal infectious disease. Accumulations of macrophages are found in infected sites; thus, we hypothesized that a marker of activated macrophages may be related to prognosis of pulmonary TB (PTB).
Yuzo Suzuki   +13 more
openalex   +2 more sources

Cooperative stimulation of dendritic cells by Cryptococcus neoformans mannoproteins and CpG oligodeoxynucleotides. [PDF]

open access: yesPLoS ONE, 2008
While mannosylation targets antigens to mannose receptors on dendritic cells (DC), the resultant immune response is suboptimal. We hypothesized that the addition of toll-like receptor (TLR) ligands would enhance the DC response to mannosylated antigens ...
Jennifer M Dan   +3 more
doaj   +12 more sources

Macrophage Activation Markers, Soluble CD163 and Mannose Receptor, in Liver Fibrosis. [PDF]

open access: yesFront Med (Lausanne), 2020
Macrophages are essential components of the human host immune system, which upon activation facilitates a broad pallet of immunomodulatory events including release of pro- or anti-inflammatory cytokines and chemokines, restoration of immune homeostasis ...
Gantzel RH   +6 more
europepmc   +2 more sources

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