Results 21 to 30 of about 82,856 (307)
An Extended Conformation of the Macrophage Mannose Receptor [PDF]
Journal of Biological Chemistry, 2001 The macrophage mannose receptor mediates phagocytosis of pathogenic microorganisms and endocytosis of potentially harmful soluble glycoproteins by recognition of their defining carbohydrate structures. The mannose receptor is the prototype for a family of receptors each having an extracellular region consisting of 8-10 domains related to C-type ...
Catherine E. Napper +2 more
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Characterization of functional mannose receptor in a continuous hybridoma cell line
BMC Immunology, 2012 Background The mannose receptor is the best described member of the type I transmembrane C-type lectins; however much remains unanswered about the biology of the receptor.
Vigerust David J +2 more
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Molecules, 2019 Macrophages play an important role in the regulation of inflammation and immune response as well as the pathogenesis of chronic inflammatory diseases and cancer.
Kai Shibaguchi +5 more
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The Mannose Receptor Is Involved in the Phagocytosis of Mycobacteria-Induced Apoptotic Cells
Journal of Immunology Research, 2016 Upon Mycobacterium tuberculosis infection, macrophages may undergo apoptosis, which has been considered an innate immune response. The pathways underlying the removal of dead cells in homeostatic apoptosis have been extensively studied, but little is ...
Teresa Garcia-Aguilar +3 more
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The mannose receptor mediates dengue virus infection of macrophages. [PDF]
PLoS Pathogens, 2008 Macrophages (MØ) and mononuclear phagocytes are major targets of infection by dengue virus (DV), a mosquito-borne flavivirus that can cause haemorrhagic fever in humans. To our knowledge, we show for the first time that the MØ mannose receptor (MR) binds
Joanna L Miller +6 more
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Binding Properties of the Mannose Receptor
Immunobiology, 2001 A comprehensive approach to the study of mannose receptor (MR) biology has unveiled an unexpected level of complexity and stresses the importance of post-translational modifications and gene regulation in the analysis of protein function. The existence of endogenous tissue ligands for the MR highlights the need to reduce MR expression in antigen ...
Siamon Gordon +3 more
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Mannose receptor regulates motility [PDF]
The Journal of Cell Biology, 2006 ![Graphic][1] Myoblasts fail to fuse if they lack the mannose receptor (bottom). If myoblasts are to fuse with nascent myotubes and thus form muscles, they must apparently migrate and chew up extracellular matrix (ECM), according to Jansen and Pavlath (page [403][2 ...
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Stage-specific sampling by pattern recognition receptors during Candida albicans phagocytosis.
PLoS Pathogens, 2008 Candida albicans is a medically important pathogen, and recognition by innate immune cells is critical for its clearance. Although a number of pattern recognition receptors have been shown to be involved in recognition and phagocytosis of this fungus ...
Sigrid E M Heinsbroek +5 more
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Frontiers in Plant Science, 2021 Gaucher disease is an inherited lysosomal storage disorder caused by a deficiency of functional enzyme β-glucocerebrosidase (GCase). Recombinant GCase has been used in enzyme replacement therapy to treat Gaucher disease. Importantly, the terminal mannose
Naphatsamon Uthailak +7 more
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Carbohydrate recognition by the mannose-6-phosphate receptors [PDF]
Current Opinion in Structural Biology, 2009 The two P-type lectins, the 46kDa cation-dependent mannose-6-phosphate (Man-6-P) receptor (CD-MPR), and the 300kDa cation-independent Man-6-P receptor (CI-MPR), are the founding members of the growing family of mannose-6-phosphate receptor homology (MRH) proteins.
Linda J. Olson +2 more
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