Results 31 to 40 of about 222,900 (341)
MAP3K kinases and kidney injury
Nefrología (English Edition), 2019 Mitogen-activated protein kinases (MAP kinases) are functionally connected kinases that regulate key cellular process involved in kidney disease such as all survival, death, differentiation and proliferation.
Leticia Cuarental +7 more
doaj +3 more sources
Journal of Lipid Research, 2001 This study was conducted on human Jurkat T cell lines to elucidate the role of EPA and DHA, n-3 PUFA, in the modulation of two mitogen-activated protein (MAP) kinases, that is, extracellular signal-regulated kinases 1 and 2 (ERK1 and ERK2).
Anne Denys +2 more
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Journal of Biological Chemistry, 1993 Xenopus 45-kDa mitogen-activated protein (MAP) kinase kinase (MAPKK) is a serine/threonine/tyrosine kinase, which activates MAP kinase (MAPK) by phosphorylating its threonine and tyrosine residues. MAPKK is active only when its threonine and/or serine residues are phosphorylated.
S, Matsuda, Y, Gotoh, E, Nishida
openaire +2 more sources
An evolutionary perspective on the kinome of malaria parasites [PDF]
, 2012 Malaria parasites belong to an ancient lineage that diverged very early from the main branch of eukaryotes. The approximately 90-member plasmodial kinome includes a majority of eukaryotic protein kinases that clearly cluster within the AGC, CMGC, TKL ...
Andrew B. Tobin +6 more
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Expression of Novel Kinase MAP3K19 in Various Cancers and Survival Correlations
Frontiers in Bioscience-Landmark, 2022 Mitogen Activated Protein (MAP) kinases are a category of serine/threonine kinases that have been demonstrated to regulate intracellular events including stress responses, developmental processes, and cancer progression Although many MAP kinases have ...
Khoa Nguyen +20 more
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Analysis of somatic mutations across the kinome reveals loss-of-function mutations in multiple cancer types [PDF]
, 2017 In this study we use somatic cancer mutations to identify important functional residues within sets of related genes. We focus on protein kinases, a superfamily of phosphotransferases that share homologous sequences and structural motifs and have many ...
Bose, Ron, Kumar, Runjun D
core +2 more sources
BMC Genomics, 2006 Background As in other eukaryotes, plant mitogen-activated protein kinase (MAPK) cascades are composed of three classes of hierarchically organized protein kinases, namely MAPKKKs, MAPKKs, and MAPKs.
Ellis Brian E +5 more
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Molecules, 2021 The purpose of this work is to investigate the protein kinase inhibitory activity of constituents from Acacia auriculiformis stem bark. Column chromatography and NMR spectroscopy were used to purify and characterize betulin from an ethyl acetate soluble ...
Augustine A. Ahmadu +16 more
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Signaling pathways for transduction of the initial message of the glycocode into cellular responses [PDF]
, 1998 The sugar units of glycan structures store information and establish an alphabet of life. The language of the oligosaccharide coding units is deciphered by receptors such as lectins and the decoded message can be transduced by multiple signaling pathways.
Gabius, Hans-Joachim, Villalobo, A.
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BWMK1, a Novel MAP Kinase Induced by Fungal Infection and Mechanical Wounding in Rice
Molecular Plant-Microbe Interactions, 1999 The activation of the mitogen-activated protein (MAP) kinases by different environmental stresses has been previously observed in several dicot plant species. Here, we report the isolation of a novel MAP kinase in rice that is induced during infection by
Chaozu He +3 more
doaj +1 more source