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Total synthesis and bioactivities of two proposed structures of maresin

open access: yesTotal synthesis and bioactivities of two proposed structures of maresin
Maresin is a potent anti-inflammatory lipid mediator derived from docosahexaenoic acid (DHA). A highly convergent total synthesis of two proposed structures of C7-epimeric maresins from the four known fragments was achieved in 17 steps. The three key coupling reactions were the BF3-mediated alkyne attack on the epoxide, chiral titanium complex-promoted
openaire  

SPMs exert anti-inflammatory and pro-resolving effects through positive allosteric modulation of the prostaglandin EP4 receptor. [PDF]

open access: yesProc Natl Acad Sci U S A
Alnouri MW   +14 more
europepmc   +1 more source

Inflammation dynamics modulate periodontal stem cell fate and function. [PDF]

open access: yesFront Immunol
Alves T   +3 more
europepmc   +1 more source

Proresolving Lipid Mediators in the Respiratory System. [PDF]

open access: yesAnnu Rev Physiol
Serhan CN, Levy BD.
europepmc   +1 more source

Inflammation and Resolution in Obesity-Related Cardiovascular Disease. [PDF]

open access: yesInt J Mol Sci
Karakasis P   +7 more
europepmc   +1 more source

Crosstalk between renin and arachidonic acid (and its metabolites). [PDF]

open access: yesLipids Health Dis
Das UN   +4 more
europepmc   +1 more source

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