Angiotensin-(1-7) and Mas receptor in the brain [PDF]
Exploration of Medicine, 2021 The renin-angiotensin system (RAS) is a key regulator of blood pressure and electrolyte homeostasis. Besides its importance as regulator of the cardiovascular function, the RAS has also been associated to the modulation of higher brain functions ...
Natalia L. Rukavina Mikusic +2 more
doaj +3 more sources
Mas-related G-protein–coupled receptors inhibit pathological pain in mice [PDF]
Proceedings of the National Academy of Sciences, 2010 An important objective of pain research is to identify novel drug targets for the treatment of pathological persistent pain states, such as inflammatory and neuropathic pain.
Altier +49 more
core +6 more sources
Mas Receptor Blockade Promotes Renal Vascular Response to Ang II after Partial Kidney Ischemia/Reperfusion in a Two-Kidney-One-Clip Hypertensive Rats Model. [PDF]
Int J Nephrol, 2021 Karimi F, Nematbakhsh M.
europepmc +3 more sources
An ACE2/Mas-related receptor MrgE axis in dopaminergic neuron mitochondria
Redox Biology, 2021 ACE2 plays a pivotal role in the balance between the pro-oxidative pro-inflammatory and the anti-oxidative anti-inflammatory arms of the renin-angiotensin system. Furthermore, ACE2 is the entry receptor for SARS-CoV-2.
Rita Valenzuela +9 more
doaj +4 more sources
Mitigating Cardiotoxicity of Dendrimers: Angiotensin-(1-7) via Its Mas Receptor Ameliorates PAMAM-Induced Cardiac Dysfunction in the Isolated Mammalian Heart. [PDF]
Pharmaceutics, 2022 Akhtar S +3 more
europepmc +3 more sources
Renal vascular response to angiotensin 1-7 in rats: the role of Mas receptor [PDF]
Research in Pharmaceutical Sciences, 2018 Recently a cross talk between angiotensin 1-7 (Ang1-7) receptor (MasR) and angiotensin II receptors types 1 and 2 (AT1R and AT2R) has been highlighted. The effects of MasR antagonist (A779) compared to the vehicle on the renal blood flow (RBF) and renal ...
Mehdi Nematbakhsh, Azam Mansouri
doaj +2 more sources
PLoS ONE, 2015 Angiotensin 1-7 (Ang 1-7) counter-regulates the cardiovascular actions of angiotensin II (Ang II). The present study investigated the protective effect of Ang 1-7 against Ang II-induced endoplasmic reticulum (ER) stress and endothelial dysfunction.
Dharmani Murugan +4 more
doaj +2 more sources
The Vasoactive Mas Receptor in Essential Hypertension. [PDF]
J Clin Med, 2020 The renin–angiotensin–aldosterone system (RAAS) has been studied extensively, and with the inclusion of novel components, it has become evident that the system is much more complex than originally anticipated. According to current knowledge, there are two main axes of the RAAS, which counteract each other in terms of vascular control: The classical ...
Povlsen AL +4 more
europepmc +5 more sources
Journal of Mazandaran University of Medical Sciences, 2020 Background and purpose: Chronic kidney disease is among the common diseases in the world. Studies show that women are more protected against renal diseases compared to men. On the other hand, vasodilatory axises of renin angiotensin system (angiotensin 1-
Shadan Saberi +2 more
doaj +2 more sources
Validation of commercial Mas receptor antibodies for utilization in Western Blotting, immunofluorescence and immunohistochemistry studies. [PDF]
PLoS ONE, 2017 Mas receptor (MasR) is a G protein-coupled receptor proposed as a candidate for mediating the angiotensin (Ang)-converting enzyme 2-Ang (1-7) protective axis of renin-angiotensin system.
Valeria Burghi +10 more
doaj +2 more sources