Results 31 to 40 of about 46,299 (322)

Interaction Between Mas and the Angiotensin AT1 Receptor in the Amygdala

Journal of Neurophysiology, 2000
The Mas-protooncogene is a maternally imprinted gene encoding an orphan G protein–coupled receptor expressed mainly in limbic structures of the rodent CNS.
Michael Bader, Doris Albrecht, Oliver Von Bohlen Und Halbach, Thomas Walther   +3 more
core   +3 more sources

Activation of central Angiotensin-(1-7)/Mas receptor alleviates synaptic damage in diabetes-associated cognitive impairment via modulating AKT/FOXO1/PACAP axis. [PDF]

Int J Biol Sci
Tian S, Wu T, Zhang Z, Lv S, Ji X, Zhao Z, Ma X, Wang J, Bi Y.   +8 more
europepmc   +3 more sources

Interaction Between the Angiotensin-(1–7) Mas Receptor and the Dopamine D2 Receptor [PDF]

Hypertension, 2021
Ang (angiotensin) 1–7 MasR (Mas receptor) and D2R (dopamine D2 receptor) stimulation is coupled to anti-inflammatory responses. In the present work, we investigated the hypothesis that the anti-inflammatory action mediated by both receptors results from MasR-D2R heteromerization. Human monocyte (THP-1) cells differentiated to macrophages and exposed to
Natalia L. Rukavina Mikusic, Mauro G. Silva, Luciana R. Mazzitelli, Robson A.S. Santos, Karina A. Gómez, Hernán E. Grecco, Mariela M. Gironacci   +6 more
openaire   +4 more sources

Glycosylated Ang-(1-7) MasR Agonist Peptide Poly Lactic-co-Glycolic Acid (PLGA) Nanoparticles and Microparticles in Cognitive Impairment: Design, Particle Preparation, Physicochemical Characterization, and In Vitro Release

Pharmaceutics, 2022
Heart failure (HF) causes decreased brain perfusion in older adults, and increased brain and systemic inflammation increases the risk of cognitive impairment and Alzheimer’s disease (AD).
David Encinas-Basurto, John P. Konhilas, Robin Polt, Meredith Hay, Heidi M. Mansour   +4 more
doaj   +1 more source

Renin-Angiotensin System: A Review of Historical Perspectives

Galician Medical Journal, 2023
The article is a review of publications concerning historical perspectives of the renin-angiotensin system. The discovery of its components is presented in chronological order, beginning with the initial identification of renin and proceeding to the ...
Olga Kovalyova, Anna Zhuravlyova, Svitlana Ivanchenko   +2 more
doaj   +1 more source

Angiotensin-(1-7) receptor Mas is an essential modulator of extracellular matrix protein expression in the heart

Regulatory Peptides, 2012
Carlos Henrique De Castro, Anderson J Ferreira, Natalia Alenina   +2 more
exaly   +3 more sources

Lateral Preoptic Area Neurons Activated by Angiotensin-(1–7) Increase Intravesical Pressure: A Novel Feature in Central Micturition Control

Frontiers in Physiology, 2021
Central micturition control and urine storage involve a multisynaptic neuronal circuit for the efferent control of the urinary bladder. Electrical stimulation of the lateral preoptic area (LPA) at the level of the decussation of the anterior commissure ...
Gustavo B. Lamy, Eduardo M. Cafarchio, Bárbara do Vale, Bruno B. Antonio, Daniel P. Venancio, Janaina S. de Souza, Rui M. Maciel, Gisele Giannocco, Gisele Giannocco, Patrik Aronsson, Monica A. Sato   +10 more
doaj   +1 more source

The MA Helix Is Important for Receptor Assembly and Function in the α4β2 nACh Receptor

Membranes, 2023
Pentameric ligand-gated ion channels (pLGICs) are expressed throughout the central and peripheral nervous systems of vertebrates and modulate many aspects of human health and disease. Recent structural and computational data indicate that cation-selective pLGICs contain a long helical extension (MA) of one of the transmembrane helices. The MA helix has
Dorottya I. Fricska, Susanne M. Mesoy, Sarah C. R. Lummis   +2 more
openaire   +4 more sources

A comparison between virus- versus patients-centred therapeutic attempts to reduce COVID-19 mortality

Emerging Microbes and Infections, 2021
Since December 2019, coronavirus disease 2019 (COVID-19), caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has changed our lives.
Serge Camelo, Mathilde Latil, Sam Agus, Waly Dioh, Stanislas Veillet, René Lafont, Pierre J. Dilda   +6 more
doaj   +1 more source

Alterações cardiovasculares induzidas por fenilefrina em animais Knockout para o receptor Mas

, 2011
Sympathetic activation is modulated by adrenergic receptors and stimulation of these receptors by excessive circulating catecholamines causes cardiac remodeling, with consequent deterioration of myocardial function. It is known that the Renin-Angiotensin
Amanda Parreira
openalex   +2 more sources