Results 21 to 30 of about 46,299 (322)
Increased vascular sympathetic modulation in mice with Mas receptor deficiency [PDF]
Journal of the Renin-Angiotensin-Aldosterone System, 2016 Introduction: The angiotensin-converting enzyme 2 (ACE2)/angiotensin (Ang)-(1–7)/Mas axis could modulate the heart rate (HR) and blood pressure variabilities (BPV) which are important predictors of cardiovascular risk and provide information about the ...
Ravizzoni Dartora, D. +17 more
core +6 more sources
Endothelin-1 downregulates Mas receptor expression in human cardiomyocytes
Molecular Medicine Reports, 2013 Endothelin-1 (ET-1) and the renin-angiotensin system (RAS) are involved in the pathogenesis of cardiac dysfunction. The Mas receptor is a functional binding site for angiotensin (Ang)‑(1-7), which is now considered a critical component of the RAS and exerts cardioprotective effects.
Zhiheng Chen +6 more
openalex +5 more sources
Mas Receptor Blockade Promotes Renal Vascular Response to Ang II after Partial Kidney Ischemia/Reperfusion in a Two-Kidney-One-Clip Hypertensive Rats Model. [PDF]
Int J Nephrol, 2021 Karimi F, Nematbakhsh M.
europepmc +3 more sources
Angiotensin-(1-7) and the g protein-coupled receptor MAS are key players in renal inflammation. [PDF]
PLoS ONE, 2009 Angiotensin (Ang) II mediates pathophysiologial changes in the kidney. Ang-(1-7) by interacting with the G protein-coupled receptor Mas may also have important biological activities.In this study, renal deficiency for Mas diminished renal damage in ...
Vanesa Esteban +11 more
doaj +3 more sources
Peptides, 2012 The Mas protooncogene encodes a G protein-coupled receptor that has been described as a functional receptor for the cardioprotective fragment of the renin-angiotensin system (RAS), Angiotensin (Ang)-(1-7).
Marco Fabricio Dias-Peixoto +2 more
exaly +2 more sources
Mitigating Cardiotoxicity of Dendrimers: Angiotensin-(1-7) via Its Mas Receptor Ameliorates PAMAM-Induced Cardiac Dysfunction in the Isolated Mammalian Heart. [PDF]
Pharmaceutics, 2022 Akhtar S +3 more
europepmc +3 more sources
Renal vascular response to angiotensin 1-7 in rats: the role of Mas receptor [PDF]
Research in Pharmaceutical Sciences, 2018 Recently a cross talk between angiotensin 1-7 (Ang1-7) receptor (MasR) and angiotensin II receptors types 1 and 2 (AT1R and AT2R) has been highlighted. The effects of MasR antagonist (A779) compared to the vehicle on the renal blood flow (RBF) and renal ...
Mehdi Nematbakhsh, Azam Mansouri
doaj +2 more sources
Mas is a G protein-coupled receptor (GPCR) that binds to Angiotensin (1-7) and it is evaluated as an important element of non classical Renin Angiotensin System. While the RAS axis has been considered as pro-inflammatory and pro-nociceptive by leveraging
Shalu Devi +2 more
openalex +3 more sources
, 2007 Cardiac remodelling occurs through cellular alterations in different physiological and pathological conditions which are still poorly understood. The reninangiotensin system is known to have an important role in this process. The recent identification of
Marco Fabrício Dias‐Peixoto
core +3 more sources
PLoS ONE, 2015 Angiotensin 1-7 (Ang 1-7) counter-regulates the cardiovascular actions of angiotensin II (Ang II). The present study investigated the protective effect of Ang 1-7 against Ang II-induced endoplasmic reticulum (ER) stress and endothelial dysfunction.
Dharmani Murugan +4 more
doaj +2 more sources