Results 91 to 100 of about 170,722 (268)

Caspase‐dependent and ‐independent apoptosis of mast cells induced by withdrawal of IL‐3 is prevented by Toll‐like receptor 4‐mediated lipopolysaccharide stimulation [PDF]

, 2003
Hideshi Yoshikawa, Kachio Tasaka, Hideshi Yoshikawa, Kachio Tasaka   +3 more
openalex   +1 more source

A Multicenter Validation of a Fully Automated Chemiluminescence Immunoassay for Plasma Elafin in Psoriasis Diagnosis and Severity Assessment

Advanced Science, EarlyView.
The fully automated CLIA demonstrates high sensitivity and specificity for plasma Elafin, achieving 88% diagnostic accuracy and an AUC of 0.92 for psoriasis detection in a multicenter cohort. The assay reliably distinguishes psoriasis from other dermatoses, objectively stratifies disease severity, and allows longitudinal monitoring, supporting its ...
Jingkun Yi, Meng Xu, Ling Han, Zhining Dong, Ruimin Liu, Xiaomei Zhang, Di Hu, Chuanjian Lu, Xiaobo Yu   +8 more
wiley   +1 more source

Degradation of the heparin matrix of mast cell granules by cultured fibroblasts. [PDF]

, 1983
F.M. Atkins, DD Metcalfe
openalex   +1 more source

Adverse roles of mast cell chymase-1 in COPD [PDF]

, 2022
Liu Gang, Andrew G Jarnicki, Keshav R. PAUDEL, Wenying Lu, Ridhima Wadhwa, Ashleigh M Philp, Hannelore Van Eeckhoutte, Jacqueline E. Marshall, Vamshikrishna Malyla, Angelica Katsifis, Michael Fricker, Nicole G Hansbro, Kamal Dua, Nazanin Z. Kermani, Mathew S. Eapen, Angelica Tiotiu, K. Fan Chung, Gaetano Caramori, Ken Bracke, Ian M Adcock, Sukhwinder S Sohal, Peter A. Wark, Brian G. Oliver, Philip M Hansbro, Liu Gang, Andrew G Jarnicki, Keshav R. PAUDEL, Wenying Lu, Ridhima Wadhwa, Ashleigh M Philp, Hannelore Van Eeckhoutte, Jacqueline E. Marshall, Vamshikrishna Malyla, Angelica Katsifis, Michael Fricker, Nicole G Hansbro, Kamal Dua, Nazanin Z. Kermani, Mathew S. Eapen, Angelica Tiotiu, K. Fan Chung, Gaetano Caramori, Ken Bracke, Ian M Adcock, Sukhwinder S Sohal, Peter A. Wark, Brian G. Oliver, Philip M Hansbro   +47 more
openalex   +1 more source

Novel Role of Gut‐Derived Roseburia Intestinalis in Safeguarding Intestinal Barrier Integrity and Microenvironment Homeostasis During Arsenic Exposure

Advanced Science, EarlyView.
Arsenic exposure disrupts intestinal barriers and gut microenvironment. Fecal microbiota transplantation (FMT) alleviates arsenic‐induced damage, with gut‐derived Roseburia intestinalis (R.i) identified as a key protective strain. R.i administration counters arsenic toxicity through immunomodulatory pathways and metabolites.
Lixiao Zhou, Chunsong Wang, Jieying Gao, Xu Wu, Geng Li, Xuejun Jiang, Yinyin Xia, Jun Zhang, Bo Lv, Feng Zhao, Hongyang Zhang, Huifeng Pi, Jingfu Qiu, Shangcheng Xu, Zhen Zou, Chengzhi Chen   +15 more
wiley   +1 more source

INDUCTION OF CELLULAR MOVEMENTS IN MAST CELLS BY COLCHICINE TREATMENT [PDF]

, 1966
Jacques Padawer
openalex   +1 more source

Glucocorticoid Receptor Activation Reprograms NK Cells to Drive AREG‐Mediated Immunosuppression: A Pan‐Cancer Role for AREG

Advanced Science, EarlyView.
Natural killer cells, central to anti‐tumor defense, undergo unexpected reprogramming within the tumor microenvironment. Instead of producing IFN‐γ and TNF‐α, they elevate amphiregulin, a tumor‐promoting factor. This shift is linked to glucocorticoid receptor activity and prostaglandin signaling.
Qin Wei, Guirong Liang, Rui zeng, Yuancheng Li, Anlan Hong, Hongsheng Wang, Suying Feng, Yan Wang, Yetao Wang   +8 more
wiley   +1 more source

Overcoming EGFR‐Mediated Dendritic Cell Dysfunction to Enhance Anti‐tumor Immunity in EGFR‐Mutant NSCLC by Precisely Targeting CD73 With pH‐responsive Nanocarriers

Advanced Science, EarlyView.
EGFR mutations drive ERK/c‐Jun–mediated transcriptional activation of CD73, elevating adenosine levels and fostering an immunosuppressive TME by impairing DC maturation and CD8⁺ T cell priming. The pH‐responsive nanodrug F127ZIF‐8AB680 selectively inhibits CD73, normalizes adenosine metabolism, and re‐establishes effective anti‐tumor immunity ...
Xiaoling Shang, Xudong Geng, Zixu Wang, Shumin Yuan, Shanshan Ding, Ni Liu, Xinchun Ma, Xuan Sun, Huimin Wang, Ying Sun, Xun Qu, Guangwen Ren, Yong Qiang Li, Xiuwen Wang, Yanguo Liu   +14 more
wiley   +1 more source

T Cell Exhaustion and Dendritic Cell‐Mediated Tertiary Lymphoid Structures (TLSs) Modulation Affect Response to Neoadjuvant Chemoradiotherapy in Microsatellite Stable Rectal Cancer

Advanced Science, EarlyView.
Using multi‐omics analysis, this study demonstrates that immune characteristics of the tumor microenvironment, rather than mutational profiles, are more strongly correlated with treatment response. Specifically, early exhausted T cells and tertiary lymphoid structures regulation by LAMP3⁺ dendritic cells emerge as key predictors of favorable outcomes ...
Miao Wang, Jiejun Shi, Kai Xu, Leyi Yu, Xiaomao Yin, Jiexuan Wang, Lin Zhu, Xin Yang, Jingjing Qian, Wenqiang Wang, Liangchen Zhu, Xuan Dai, Zekun Zhao, Jinran Wu, Dongsheng Li, Zhiqian Hu, Qi Huang, Xinxing Li   +17 more
wiley   +1 more source

Activation of ryanodine-sensitive calcium store drives pseudo-allergic dermatitis via Mas-related G protein-coupled receptor X2 in mast cells

, 2023
Zhao Wang, Xi Zhao, Hongmei Zhou, Delu Che, Xiaojie Du, Dan Ye, Weihui Zeng, Songmei Geng, Zhao Wang, Xi Zhao, Hongmei Zhou, Delu Che, Xiaojie Du, Dan Ye, Weihui Zeng, Songmei Geng   +15 more
openalex   +1 more source