Results 101 to 110 of about 304,209 (218)

SLC10A4 regulates IgE-mediated mast cell degranulation in vitro and mast cell-mediated reactions in vivo

Scientific Reports, 2017
Mast cells act as sensors in innate immunity and as effector cells in adaptive immune reactions. Here we demonstrate that SLC10A4, also referred to as the vesicular aminergic-associated transporter, VAAT, modifies mast cell degranulation.
Hanna Pettersson, Behdad Zarnegar, Annika Westin, Viktor Persson, Christiane Peuckert, Jörgen Jonsson, Jenny Hallgren, Klas Kullander   +7 more
doaj   +1 more source

Globule leukocytes and mast cells in the rat trachea: their number, distribution, and response to compound 48/80 and dexamethasone. [PDF]

, 1988
Globule leukocytes in the epithelium of the rat trachea may be counterparts of mucosal mast cells that are located in the gastrointestinal tract. If they are indeed similar to mucosal mast cells, globule leukocytes would be expected to decrease in number
Calonico, LD, McDonald, DM, Nadel, JA, Tam, EK   +3 more
core  

Mast cells and canine mast cell tumours. A review [PDF]

Veterinary Quarterly, 2004
This article reviews the literature on mast cells and tumours derived from mast cells in the dog. Mast cells play a central role in inflammatory and immune reactions. Mast cells, normal and neoplastic, contain and release important biologically active substances: heparin, histamine, eosinophilic chemotactic factor and proteolytic enzymes.
openaire   +2 more sources

Structural and functional interaction between polyamine related molecules and biological membranes [PDF]

, 2016
La comunicación describe el conocimiento actual sobre las interacciones de biomoléculas relacionadas con el metabolismo de poliaminas con las estructuras y funciones de las membranas biológicasChanges induced by PA on nucleic acid (NA) conformation and ...
Acosta-Andrade, Carlos, Artetxe, I, Fajardo-Paredes, Ignacio José, Goñi, Félix, Lete, MG, Ruiz-Mirazo, Kepa, Sanchez-Jimenez, Francisca Maria, Urdiales-Ruiz, Jose Luis   +7 more
core  

Granzyme B from mast cells contributes to choroidal neovascularization in a model of wet age-related macular degeneration

Frontiers in Immunology
PurposeWet age-related macular degeneration (AMD) is characterized by choroidal neovascularization (CNV), yet current anti-VEGF therapies are ineffective in many patients.
Manjosh Uppal, Amir Hosseini, Khola Bilal, Neilan Tan, Zhengyuan Ai, Wania Khan, Isa Samad, Gurmohit Gill, Hyung-Suk Yoo, Harshini Chakravarthy, Chuan-Hui Kuo, Jeanne Xi, David J. Granville, Joanne A. Matsubara   +13 more
doaj   +1 more source

The phosphoinositide 3-kinase-dependent activation of Btk is required for optimal eicosanoid production and generation of reactive oxygen species in antigen-stimulated mast cells

, 2008
Activated mast cells are a major source of the eicosanoids PGD(2) and leukotriene C(4) (LTC(4)), which contribute to allergic responses. These eicosanoids are produced following the ERK1/2-dependent activation of cytosolic phospholipase A(2), thus ...
Beaven, Michael A., Gilfillan, Alasdair M., Kim, Mi-Sun, Kuehn, Hye Sun, Metcalfe, Dean D., Swindle, Emily J.   +5 more
core   +1 more source

Mast cell disease [PDF]

Postgraduate Medical Journal, 1967
T I, McBride, G A, McDonald, W P, Duguid
openaire   +2 more sources

Evidence for dysbiosis in the gut microbiome of patients with systemic mastocytosis

Journal of Allergy and Clinical Immunology: Global
Background: Limited research studies have investigated the role of the gut microbiome in systemic mastocytosis (SM), which is characterized by an aberrant expansion of clonal mast cells in specific tissues including the skin, marrow, liver, and the ...
Lauren E. Krausfeldt, PhD, Vivian Cao, MS, Richard Rodrigues, PhD, Wendy A. Henderson, PhD, Robin Eisch, RN, Linda M. Scott, LNP, Dean D. Metcalfe, MD, MS, Hirsh D. Komarow, MD   +7 more
doaj   +1 more source

Histamine and TNF-a release by rat peritoneal mast cells [PDF]

, 2011
Mast cells have been reported to be predominant in the vaginal smears of patients infected with T. vaginalis. In this study, we investigated whether T. vaginalis could induce mast cells to migrate and to produce TNF-alpha and histamine.
���������
core  

Changes in mast cells and in permeability of mesenteric microvessels under the effect of immobilization and electrostimulation [PDF]

It was shown that a reduction in the amount of mast cells in the mesentery and an increase in their degranulation was accompanied by an increase in vascular permeability of rat mesentery.
Gorizontova, M. P.
core   +1 more source