Results 31 to 40 of about 10,829,007 (362)
Mast Cell, the Neglected Member of the Tumor Microenvironment: Role in Breast Cancer
Journal of Immunological Research, 2018 Mast cells are unique tissue-resident immune cells that secrete a diverse array of biologically active compounds that can stimulate, modulate, or suppress the immune response.
Angélica Aponte-López +3 more
semanticscholar +1 more source
BMC Immunology, 2010 Background Mast cells have recently gained new importance as immunoregulatory cells that are involved in numerous pathological processes. One result of these processes is an increase in mast cell numbers at peripheral sites.
Pastor Maria +8 more
doaj +1 more source
Perivascular mast cells regulate vein graft neointimal formation and remodeling [PDF]
PeerJ, 2015 Objective. Emerging evidence suggests an important role for mast cells in vein graft failure. This study addressed the hypothesis that perivascular mast cells regulate in situ vascular inflammatory and proliferative responses and subsequent vein graft ...
Junxi Wu +9 more
doaj +2 more sources
Marine Drugs, 2018 UV light, especially UVB, is known as a trigger of allergic reaction, leading to mast cell degranulation and histamine release. In this study, phlorotannin Fucofuroeckol-A (F-A) derived from brown algal Ecklonia stolonifera Okamura was evaluated for its ...
Thanh-Sang Vo +7 more
semanticscholar +1 more source
The mast cell and mast cell disease
Journal of the American Academy of Dermatology, 1995 Mast cell disease or mastocytosis is a heterogeneous group of clinical disorders characterized by the proliferation and accumulation of mast cells in a variety of tissues, most often the skin. The signs and symptoms of mast cell disease are varied, dependent on the localization of mast cells in different organs and the local and systemic effects of ...
J, Longley, T P, Duffy, S, Kohn
openaire +2 more sources
Mast Cell: A Multi-Functional Master Cell
Frontiers in Immunology, 2016 Mast cells are immune cells of the myeloid lineage and are present in connective tissues throughout the body. The activation and degranulation of mast cells significantly modulates many aspects of physiological and pathological conditions in various ...
Melissa Krystel-Whittemore +2 more
semanticscholar +1 more source
Rapid Mast Cell Generation from Gata2 Reporter Pluripotent Stem Cells
Stem Cell Reports, 2018 Summary: Mast cells are tissue-resident immune cells. Their overgrowth/overactivation results in a range of common distressing, sometimes life-threatening disorders, including asthma, psoriasis, anaphylaxis, and mastocytosis. Currently, drug discovery is
Mari-Liis Kauts +13 more
doaj +1 more source
Cell Communication and Signaling, 2018 Mast cells may activate fibroblasts and contribute to remodeling processes in the lung. However, the mechanism behind these actions needs to be further investigated. Fibroblasts are major regulators of on-going remodeling processes.
Mariam Bagher +5 more
semanticscholar +1 more source
Frontiers in Neuroscience, 2017 Mast cells are localized throughout the body and mediate allergic, immune, and inflammatory reactions. They are heterogeneous, tissue-resident, long-lived, and granulated cells.
D. Kempuraj +9 more
semanticscholar +1 more source
Mediators of Inflammation, 2016 Mast cells are primary effector cells of allergy, and recruitment of mast cells in involved tissue is one of the key events in allergic inflammation. Tryptase is the most abundant secretory product of mast cells, but little is known of its influence on ...
Xin Liu +8 more
doaj +1 more source