Results 51 to 60 of about 10,756,993 (383)
TH9 cells are required for tissue mast cell accumulation during allergic inflammation [PDF]
BACKGROUND: IL-9 is important for the growth and survival of mast cells. IL-9 is produced by T cells, natural killer T cells, mast cells, eosinophils, and innate lymphoid cells, although the cells required for mast cell accumulation during allergic ...
Akhtar, Nahid+6 more
core +1 more source
Mast Cells and Their Progenitors in Allergic Asthma
Mast cells and their mediators have been implicated in the pathogenesis of asthma and allergy for decades. Allergic asthma is a complex chronic lung disease in which several different immune cells, genetic factors and environmental exposures influence ...
Erika Méndez-Enríquez, Jenny Hallgren
doaj +1 more source
An Inflammation-Centric View of Neurological Disease: Beyond the Neuron [PDF]
Inflammation is a complex biological response fundamental to how the body deals with injury and infection to eliminate the initial cause of cell injury and effect repair.
Facci, Laura+3 more
core +2 more sources
Mast cells are primary effector cells of allergy, and recruitment of mast cells in involved tissue is one of the key events in allergic inflammation. Tryptase is the most abundant secretory product of mast cells, but little is known of its influence on ...
Xin Liu+8 more
doaj +1 more source
Innate Immunity Induces the Accumulation of Lung Mast Cells During Influenza Infection
Mast cells release disease-causing mediators and accumulate in the lung of asthmatics. The most common cause of exacerbations of asthma is respiratory virus infections such as influenza. Recently, we demonstrated that influenza infection in mice triggers
Behdad Zarnegar+3 more
doaj +1 more source
Arf1 facilitates mast cell proliferation via the mTORC1 pathway
Mast cells are one of major players in allergic responses. Mast cell activation via the high affinity IgE receptor (FcεRI) causes degranulation and release of de novo synthesized proinflammatory cytokines in a process that involves vesicle trafficking ...
Yui Kotani+4 more
doaj +1 more source
Mast cells are localized throughout the body and mediate allergic, immune, and inflammatory reactions. They are heterogeneous, tissue-resident, long-lived, and granulated cells.
D. Kempuraj+9 more
semanticscholar +1 more source
Mast cells and oral inflammation [PDF]
Mast cells are mobile granule-containing secretory cells that are distributed preferentially about the microvascular endothelium in oral mucosa and dental pulp. The enzyme profile of mast cells in oral tissues resembles that of skin, with most mast cells
Walsh, L. J.
core +1 more source
siRNA knockdown of SPHK1 in vivo protects mice from systemic, type-I Allergy. [PDF]
Systemic anaphylaxis is considered to be a typical immediate hypersensitivity response, determined by the activation of immune cells, via antigen-induced aggregation of IgE-sensitized FcεRI cells.
Alirio Jose A. J. Melendez+2 more
core +2 more sources
Mast cells are rare tissue-resident immune cells that are involved in allergic reactions, and their numbers are increased in the lungs of asthmatics.
Joakim S. Dahlin+6 more
semanticscholar +1 more source