Results 31 to 40 of about 12,201,289 (252)
Evaluation of Mast Cell Activation Syndromes: Impact of Pathology and Immunohistology [PDF]
, 2012 Mast cell activation syndromes (MCAS) are clinically defined disease states with a largely unknown morphological background. Since mastocytosis may be associated with MCAS, it is crucial in every patient to document or exclude mastocytosis by appropriate
Horny, H. -P., Valent, P., Sotlar, K.
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Immunity, 2019 SUMMARY Classical itch studies have focused on immunoglobulin E (IgE)-mediated mast cell activation and hista-mine release. Recently, members of the Mas-related G-protein-coupled receptor (Mrgpr) family have been identified as mast cell receptors, but ...
J. Meixiong +9 more
semanticscholar +1 more source
Frontiers in Immunology, 2021 Mast cell activators are a novel class of mucosal vaccine adjuvants. The polymeric compound, Compound 48/80 (C48/80), and cationic peptide, Mastoparan 7 (M7) are mast cell activators that provide adjuvant activity when administered by the nasal route ...
Brandi T. Johnson-Weaver +10 more
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Definitions, Criteria and Global Classification of Mast Cell Disorders with Special Reference to Mast Cell Activation Syndromes: A Consensus Proposal [PDF]
, 2011 Activation of tissue mast cells (MCs) and their abnormal growth and accumulation in various organs are typically found in primary MC disorders also referred to as mastocytosis.
Triggiani, Massimo +37 more
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House dust mites activate nociceptor-mast cell clusters to drive type 2 skin inflammation
Nature Immunology, 2019 Allergic skin diseases, such as atopic dermatitis, are clinically characterized by severe itching and type 2 immunity-associated hypersensitivity to widely distributed allergens, including those derived from house dust mites (HDMs).
N. Serhan +13 more
semanticscholar +1 more source
IL-33-mediated mast cell activation promotes gastric cancer through macrophage mobilization
Nature Communications, 2019 The contribution of mast cells in the microenvironment of solid malignancies remains controversial. Here we functionally assess the impact of tumor-adjacent, submucosal mast cell accumulation in murine and human intestinal-type gastric cancer.
M. Eissmann +16 more
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Acta Veterinaria Scandinavica, 2022 Background Mast cell density has been shown to have both enhancing and inhibiting effects on tumour progression and the ability to predict breast cancer behaviour in humans. However, prognostic results have been contradictory.
Simona Sakalauskaitė +3 more
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The dark side of mast cells and their role in metastasis [PDF]
, 2014 Komarowska Marta Diana, Korakiewicz Gabriela, Pilaszewicz Agata, Hermanowicz Adam, Reszec Joanna, Debek Wojciech, Chyczewski Lech. The dark side of mast cells and their role in metastasis. Journal of Health Sciences. 2014;4(14):273-284. ISSN 1429-9623 /
Korakiewicz, Gabriela +6 more
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Mast Cell Responses to Viruses and Pathogen Products
International Journal of Molecular Sciences, 2019 Mast cells are well accepted as important sentinel cells for host defence against selected pathogens. Their location at mucosal surfaces and ability to mobilize multiple aspects of early immune responses makes them critical contributors to effective ...
J. Marshall +2 more
semanticscholar +1 more source
Non-canonical activation of PI3Kγ by Ca²⁺/PKCβ in mast cells [PDF]
, 2014 Mast cells are key effector cells in allergic disease triggering inflammation through mediator release. Allergens activate mast cells through the high-affinity receptor for IgE (FcεRI), which initiates signalling pathways that regulate the release of
Walser, Romy
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