Results 61 to 70 of about 99 (98)

Large‐eddy simulation with Lagrangian cloud modeling and large‐scale dynamics (L3$$ {\mathrm{L}}^3 $$) for studying the marine fog life cycle

Quarterly Journal of the Royal Meteorological Society, EarlyView.
This study explores the life cycle of marine fog using a novel L3$$ {\mathrm{L}}^3 $$ coupling method, which integrates large‐eddy simulation (LES), Lagrangian cloud modeling (LCM), and large‐scale dynamics (LSD). Simulations of two fog episodes observed during the FATIMA campaign revealed key insights into the fog's microphysical and dynamic ...
Anup Barve, Ismail Gultepe, Harindra Joseph Fernando, Qing Wang, Lian Shen   +4 more
wiley   +1 more source

Potential roles of antibodies with different classes in IgG4‐related diseases

Rheumatology &Autoimmunity, EarlyView.
This review discussed the common characteristics of different classes of antibodies and their potential corresponding unique mechanisms involved in immunoglobulin G4‐related disease. Abstract Immunoglobulin G4‐related disease (IgG4‐RD), first identified two decades ago, is an immune‐mediated pro‐inflammatory and profibrotic disease entity affecting ...
Ling Li, Shaozhe Cai, Shengyan Lin, Lin Bai, Zhihua Yu, Wei Sun, Lingli Dong   +6 more
wiley   +1 more source

Interpretable Differential Abundance Signature (iDAS)

Small Methods, EarlyView.
iDAS is an ANOVA‐based framework that enhances the interpretability of differential abundance signatures in single‐cell and spatial omics data. It provides a coherent and interpretable framework for grouping gene‐level associations in complex experimental designs.
Lijia Yu, Yingxin Lin, Xiangnan Xu, Pengyi Yang, Jean Y. H. Yang   +4 more
wiley   +1 more source

The Biomaterial and Blood Clot Complex: A Crucial Early Environment for Osteo‐Coagulo‐Immunomodulation and the Advancement of Bone Biomaterials

Small Structures, EarlyView.
Various properties of bone biomaterials can modulate components of the blood clot (including the fibrin network, red blood cells, platelets, and the complement system) in vivo implantation, leading to the formation of a biomaterial–blood clot complex (BBCC) significantly impacting subsequent osteoimmunomodulation.
Zongpu Han, Jieyun Xu, Xinyu Guo, Lingyu Liang, Linjun Zhang, Yu Su, Wendong Gao, Qingming Tang, Lili Chen, Zhuofan Chen, Yin Xiao, Zetao Chen   +11 more
wiley   +1 more source

Dissecting Microscopic Colitis Immunopathophysiology: Insights From Basic Research

United European Gastroenterology Journal, EarlyView.
ABSTRACT Microscopic colitis is an inflammatory bowel disease (IBD) comprising two clinically undiscernible entities: collagenous colitis and lymphocytic colitis. Collagenous colitis associates with HLA genes and displays a Th1/Tc1–Th17/Tc17 profile with pericryptal myofibroblast activity, water malabsorption and secondary fluid loss due to altered ...
Andreas Münch, Celia Escudero‐Hernández   +1 more
wiley   +1 more source

How pandemics reshape our brain: Common links and targets between long‐haul COVID‐19, myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), oxidative stress, and neurodegeneration

Neuroprotection, EarlyView.
Mary E. Herman
wiley   +1 more source

The regulatory effects and applications of TIGIT/CD155 on the tumor microenvironment in HCC

VIEW, EarlyView.
Background The interaction between TIGIT and CD155 compromises immune cell efficacy in tumor targeting, potentially driving hepatocellular carcinoma (HCC) progression through diverse molecular pathways. What Was Done This study investigates the interplay between CD155 and TIGIT in regulating CD8+ T cell function and elucidates its implications in HCC ...
Wenting Li, Yukun Li, Yao Li, Mingqi Yang, Haichuan Peng, Hongwei Sun, Ping Jiang, Yizhun Zhu, Qiang Chen, Xiaobing Duan, Wei Zhao   +10 more
wiley   +1 more source

Circulating genomic biomarkers predict chemoradiotherapy resistance and immunotherapy response in locally advanced non‐small‐cell lung cancer

VIEW, EarlyView.
The insufficient sensitivity of single circulating tumor DNA (ctDNA)‐molecular residual disease (MRD) prediction remains unresolved and hinders the clinical implementation of ctDNA. Through prospective cohort study, independent validations, and mechanism exploration from peripheral blood and tumor tissue, we demonstrate that ctDNA‐based STK11/KEAP1 ...
Yu Wang, Canjun Li, Tao Zhang, Jianyang Wang, Wenyang Liu, Lei Deng, Ying Jiang, Jinghao Duan, Luhua Wang, Hong Ge, Nan Bi   +10 more
wiley   +1 more source

Deciphering the panvascular immune landscape of atherosclerosis

VIEW, EarlyView.
Atherosclerosis (AS) involves inflammation in major arteries and can cause severe cardiovascular events like heart attacks and strokes, yet disease patterns vary significantly between arteries, complicating diagnosis and treatment. In this study, we integrated transcriptomic and single‐cell RNA sequencing data from AS plaques across five key arterial ...
Yiming Zhong, Yifan Chen, Yuehong Wang, Wenhai Pan, Honghao Huang, Lin Lin Cao, Yili Wang, Jiawen Zhang, Yunyi Liang, Xiangyue Qian, Chenxi Shi, Xiyuan Lu, Jun Pu   +12 more
wiley   +1 more source

Spontaneous haemoperitoneum secondary to mast cell neoplasia and presumed splenic abscess rupture in a cat

Veterinary Record Case Reports, EarlyView.
Abstract A geriatric feline was presented to a university teaching hospital for lethargy and inappetence. The patient was subsequently diagnosed with spontaneous haemoperitoneum secondary to rupture of a splenic mass and was taken to surgery for splenectomy following appropriate stabilisation measures.
Jenna Collins, Nyssa Levy, Tuddow Thaiwong‐Nebelung   +2 more
wiley   +1 more source