Results 81 to 90 of about 99 (98)
Functional Ecology, EarlyView.Read the free Plain Language Summary for this article on the Journal blog. Abstract Plant phenology is crucial for understanding plant growth and climate feedback. It affects canopy structure, surface albedo, and carbon and water fluxes. While the influence of environmental factors on phenology is well‐documented, the role of plant intrinsic factors ...
Yunpeng Luo +8 more
wiley +1 more source
Journal of Animal Ecology, EarlyView.Studying the spatial ecology of ecologically relevant species supports the development of effective conservation strategies. Recent technological advancements in remote tracking methods now enable researchers to study large flower‐visiting insects and important pollinators, such as carpenter bees.
Sophie Kratschmer +12 more
wiley +1 more source
Insect Science, EarlyView.We report the first high‐quality chromosome‐level genome assembly for the aphid Uroleucon formosanum, a serious pest that infests lettuce in eastern Asia. A combination of comparative genomic analyses and RNA‐seq transcriptome profiling suggests that U. formosanum employs integrative mechanisms to cope with host plant‐derived sesquiterpene lactone (STL)
Jing‐Bo Li +3 more
wiley +1 more source
Aging Cell, Volume 24, Issue 4, April 2025.We analyzed clinical data from 2412 Golden Retrievers to examine age‐related changes and their association with mortality. A biological aging clock using blood markers achieved R = 0.78 but did not improve mortality prediction. A full biomarker model predicted lifetime (C‐index = 0.763) and 1‐year mortality (AUC = 0.817) more effectively.
Kevin Perez +3 more
wiley +1 more source
A Single‐Cell Transcriptome Atlas Characterizes the Immune Landscape of Human Testes During Aging
Aging Cell, EarlyView.This study utilized single‐cell RNA sequencing to analyze immune cells in 33 human testis samples (ages 21–69). We found age‐related alterations in monocytes and MRC1hi TRM, with shifts in phagocytosis, cytokine, and antigen presentation, contributing to low‐grade inflammation in aging. These findings provide insights into immune aging in human testis.
Qiaoling Jiang +10 more
wiley +1 more source
Aging Cell, EarlyView.Senolytic therapy restores neurovascular function, blood–brain barrier integrity, and cognitive performance in aged mice by targeting endothelial senescence. Findings highlight that brain microvascular endothelial cells are highly vulnerable to aging‐induced senescence, and early intervention in middle age may be the most effective strategy to prevent ...
Boglarka Csik +20 more
wiley +1 more source
Aging Cell, EarlyView.Expression of HIRA in embryonic melanoblasts is required for proper epigenetic programing and lineage differentiation. Although HIRA deficiency results in a mild phenotype at birth and young adulthood, the melanocytic lineage is sensitive to proliferative challenge, prone to loss of stem cells and dramatically accelerated hair greying in later life ...
Farah Jaber‐Hijazi +20 more
wiley +1 more source
Aging Cell, EarlyView.Explants of human postmenopausal ovarian cortex and medulla were treated with doxorubicin for 24 h followed by culture for up to 10 days in doxorubicin‐free medium. Single nuclei sequencing and proteomics revealed an unbiased signature of ovarian senescence driven by epithelial cells in the cortex and stromal cells in the cortex and medulla ...
Pooja Raj Devrukhkar +18 more
wiley +1 more source
Allergy, Volume 80, Issue 4, Page 1074-1085, April 2025.In Europe, Omalizumab is indicated for the treatment of moderate to severe asthma, but not for IgE‐mediated food allergy. We assessed the impact of Omalizumab on efficacy, safety, and the quality of life (FA‐QoL) in patients with moderate to severe asthma and who have a history of anaphylaxis to peanut, tree nuts, fish, egg, milk, and/or wheat.
Stefania Arasi +14 more
wiley +1 more source
Allergy, EarlyView.This study investigated the therapeutic equivalence of CT‐P39 (an omalizumab biosimilar) and EU‐approved reference omalizumab (ref‐OMA) in patients with chronic spontaneous urticaria. Therapeutic equivalence between CT‐P39 and ref‑OMA (300 mg) was demonstrated by the primary endpoint – confidence intervals of the treatment difference in mean change ...
Sarbjit S. Saini +16 more
wiley +1 more source