The Matrisome Genes From Hepatitis B–Related Hepatocellular Carcinoma Unveiled [PDF]
Hepatology Communications, 2021 Chronic hepatitis B virus (HBV) infection changes the composition of the extracellular matrix (ECM) and enables the onset and progression of hepatocellular carcinoma (HCC).
Wei Chen +8 more
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Pan-Cancer analysis of the expression and regulation of matrisome genes across 32 tumor types [PDF]
Matrix Biology Plus, 2019 The microenvironment plays a central role in cancer, and neoplastic cells actively shape it to their needs by complex arrays of extracellular matrix (ECM) proteins, enzymes, cytokines and growth factors collectively referred to as the matrisome.
Valerio Izzi +6 more
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The liver matrisome – looking beyond collagensKey points [PDF]
JHEP Reports, 2020 Summary: The extracellular matrix (ECM) is a diverse microenvironment that maintains bidirectional communication with surrounding cells to regulate cell and tissue homeostasis.
Gavin E. Arteel, Alexandra Naba
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Quantitative proteomics identifies tumour matrisome signatures in patients with non-small cell lung cancer [PDF]
Frontiers in Oncology, 2023 IntroductionThe composition and remodelling of the extracellular matrix (ECM) are important factors in the development and progression of cancers, and the ECM is implicated in promoting tumour growth and restricting anti-tumour therapies through multiple
Helen F. Titmarsh +13 more
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Microgravity Effects on the Matrisome [PDF]
Cells, 2021 Gravity is fundamental factor determining all processes of development and vital activity on Earth. During evolution, a complex mechanism of response to gravity alterations was formed in multicellular organisms.
Ludmila Buravkova +3 more
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Matrix Biology Plus, 2019 Proteins are the building blocks of life. While proteins and their localization within cells and sub-cellular compartments are well defined, the proteins predicted to be secreted to form the extracellular matrix - or matrisome - remain elusive in the ...
Alina C. Teuscher +6 more
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Deciphering cell-type-and temporally specific matrisome expression signatures in human cortical development and neurodevelopmental disorders via scRNA-seq meta-analysis [PDF]
Nature CommunicationsHuman cortical development is a complex process involving the proliferation, differentiation, and migration of progenitor cells, all coordinated within a dynamic extracellular matrix (ECM).
Do Hyeon Gim +6 more
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Immune‐related matrisomes are potential biomarkers to predict the prognosis and immune microenvironment of glioma patients [PDF]
FEBS Open Bio, 2023 The extracellular matrix (ECM) plays a vital role in the progression and metastasis of glioma and is an important part of the tumor microenvironment. The matrisome is composed of ECM components and related proteins. There have been several studies on the
Hao Yu +3 more
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A prognostic matrix gene expression signature defines functional glioblastoma phenotypes and niches [PDF]
Communications BiologyInteractions among tumor, immune, and vascular niches play major roles in glioblastoma (GBM) malignancy and treatment responses. The composition and heterogeneity of extracellular core matrix proteins (CMPs) that mediate such interactions are not well ...
Monika Vishnoi +13 more
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Novel prognostic matrisome-related gene signature of head and neck squamous cell carcinoma [PDF]
Frontiers in Cell and Developmental Biology, 2022 Background: Head and neck squamous cell carcinoma (HNSCC) is a common malignancy of the mucosal epithelium of the oral cavity, pharynx, and larynx.
Chao Huang +13 more
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