Journal of Biological Chemistry, 2017 Aberrant activation of matrix metalloproteinases (MMPs) is a common feature of pathological cascades observed in diverse disorders, such as cancer, fibrosis, immune dysregulation, and neurodegenerative diseases.
R. Scannevin +23 more
semanticscholar +1 more source
Matrix metalloproteinase 9 polymorphism and outcome after myocardial infarction
Cardiogenetics, 2011 Matrix metalloproteinase 9 (MMP9) is functionally implicated in the process of infarct healing. Several genetic variation of the MMP9 gene have been described, among which the MMP9 Arg668Gln polymorphism.
Sophie Rodius +4 more
doaj +1 more source
Matrix Metalloproteinase-1 and Matrix Metalloproteinase-9 in the Aqueous Humor of Diabetic Macular Edema Patients. [PDF]
PLoS ONE, 2016 To assess the concentrations of matrix metalloproteinase (MMP)-1 and MMP-9 in the aqueous humor of diabetic macular edema (DME) patients.The concentrations of MMP-1 and MMP-9 in the aqueous humors of 15 cataract patients and 25 DME patients were compared.
Jin-Woo Kwon, Jin A Choi, Donghyun Jee
doaj +1 more source
Frontiers in Aging Neuroscience, 2023 IntroductionPositive intracranial arterial remodelling is a dilated lesion of the large intracranial vessels; however, its pathogenesis is currently unknown.
Ming Tang +5 more
doaj +1 more source
Identification of a novel 82 kDa proMMP-9 species associated with the surface of leukaemic cells [PDF]
, 2007 MMP-9 (matrix metalloproteinase 9) plays a critical role in tumour progression. Although the biochemical properties of the secreted form of proMMP-9 are well characterized, little is known about the function and activity of cell surface-associated proMMP-
Egea, Virginia +6 more
core +1 more source
Kupffer-derived matrix metalloproteinase-9 contributes to liver fibrosis resolution
International Journal on Biological Sciences, 2018 Kupffer cells (KCs) contribute to liver fibrosis resolution by production of a large spectrum of matrix metalloproteinases (MMPs). MMP9 is a major MMP expressed by KCs. However, its role in liver fibrosis resolution remains unclear. In this study, rodent
Min Feng +5 more
semanticscholar +1 more source
Angiotensin Type 2 Receptor Stimulation Ameliorates Left Ventricular Fibrosis and Dysfunction via Regulation of Tissue Inhibitor of Matrix Metalloproteinase 1/Matrix Metalloproteinase 9 Axis and Transforming Growth Factor β1 in the Rat Heart [PDF]
, 2014 Left ventricular (LV) remodeling is the main reason for the development of progressive cardiac dysfunction after myocardial infarction (MI). This study investigated whether stimulation of the angiotensin type 2 receptor is able to ameliorate
Dahlöf, Bjorn +10 more
core +2 more sources
Matrix metalloproteinase 9 expression: new regulatory elements [PDF]
Journal of Ocular Biology, Diseases, and Informatics, 2010 Retinal ganglion cells apoptosis is linked to matrix metalloproteinase 9 (MMP-9) controlled changes of extracellular matrix. Abnormal expression of MMP-9 is associated with glaucomatous alterations. Thus, the knowledge of MMP-9 regulation is important for the understanding the pathogenesis of glaucoma.
Irina, Surgucheva +3 more
openaire +2 more sources
Journal of Oral and Maxillofacial Pathology, 2016 Matrix metalloproteinase-9 (MMP-9) is an inducible enzyme. Oral potentially malignant disorders (OPMDs) are considered as the early tissue changes that happen due to various habits such as smoking tobacco, chewing tobacco or stress.
Archana Venugopal, T. Uma Maheswari
semanticscholar +1 more source
CXCR4-targeted and MMP-responsive iron oxide nanoparticles for enhanced magnetic resonance imaging [PDF]
, 2014 MRI offers high spatial resolution with excellent tissue penetration but it has limited sensitivity and the commonly administered contrast agents lack specificity.
Aboagye, EO +7 more
core +1 more source