Results 41 to 50 of about 31,015,536 (305)

Matrix metalloproteinase-9, its inhibitor-1 and interleukines in experimental traumatic brain injury

Patologìâ, 2016
Traumatic brain injury (TBI) is accompanied by high rates of morbidity and mortality in both developed and undeveloped countries that makes it one of the most actual medical and social problems. In recent years matrix metalloproteinases are in increasing
S. V. Ziablitsev, Ya. S. Yuzkiv
doaj   +1 more source

Clinical significance of matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1 and 2 in Kawasaki disease [PDF]

Korean Journal of Pediatrics, 2010
Purpose : Kawasaki disease (KD) is a systemic vasculitis, a leading cause of pediatric acquired heart disease. Histopathological findings of coronary artery lesion (CAL) in KD indicate destruction of the coronary artery wall with diffuse vasculitis ...
Ki Wook Yun, Sin Weon Sin, Jung Ju Lee, Soo Ahn Chae, In Seok Lim, Eung Sang Choi, Byoung Hoon Yoo, Mi-Kyung Lee   +7 more
doaj   +1 more source

Assessment of Matrix Metalloproteinases a Prognostic Indicator in Advanced Fibrotic Lung Disease: A Systematic Review

Pakistan Journal of Medicine and Dentistry
Background: Fibrotic lung diseases were seen to have devastating effects among patients globally. Matrix metalloproteinases (MMP) including MMP-7, MMP-9, and MMP-1 have become promising biomarkers for idiopathic pulmonary fibrosis (IPF), and other ...
Mehvish Aqil, Saif Ur Rahman, Muhammad Zeeshan Aslam, Mostafa Ahmed Abdellah Ahmed, Ammar Ahmed, Sidra Javaid, Ehsan Ul Haq   +6 more
doaj   +1 more source

Expression of matrix metalloproteinase-2 and 9 with their inhibitors, tissue inhibitors of metalloproteinase-1 and 2 in oral lichen planus

Journal of Orofacial Sciences, 2014
Objectives: The study aims to explore the expression of the matrix metalloproteinases (MMP-2, -9) and their inhibitors (tissue inhibitors of metalloproteinase [TIMP]-1, -2) as well as the correlation between them in the different morphological forms of ...
Natheer Hashim Al-Rawi, Thaer Kassim Al-Kassam, Ahlam Hameed Majeed   +2 more
doaj   +1 more source

Plasma matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-1 as prognostic biomarkers in critically ill patients

Open Medicine, 2020
Matrix metalloproteinase 9 (MMP-9) plays an important role in inflammatory and pathological processes by enabling the inflow of leukocytes to the site of infection or tissue damage.
Duda Izabela, Krzych Łukasz, Jędrzejowska-Szypułka Halina, Lewin-Kowalik Joana   +3 more
doaj   +1 more source

Osteopontin, a Novel Substrate for Matrix Metalloproteinase-3 (Stromelysin-1) and Matrix Metalloproteinase-7 (Matrilysin) [PDF]

Journal of Biological Chemistry, 2001
Osteopontin (OPN) is a secreted phosphoprotein shown to function in wound healing, inflammation, and tumor progression. Expression of OPN is often co-localized with members of the matrix metalloproteinase (MMP) family. We report that OPN is a novel substrate for two MMPs, MMP-3 (stromelysin-1) and MMP-7 (matrilysin).
R, Agnihotri, H C, Crawford, H, Haro, L M, Matrisian, M C, Havrda, L, Liaw   +5 more
openaire   +2 more sources

Structural Basis for Matrix Metalloproteinase 1-Catalyzed Collagenolysis [PDF]

Journal of the American Chemical Society, 2012
The proteolysis of collagen triple-helical structure (collagenolysis) is a poorly understood yet critical physiological process. Presently, matrix metalloproteinase 1 (MMP-1) and collagen triple-helical peptide models have been utilized to characterize the events and calculate the energetics of collagenolysis via NMR spectroscopic analysis of 12 enzyme-
BERTINI, IVANO, FRAGAI, MARCO, LUCHINAT, CLAUDIO, MELIKIAN, MAXIME THIERRY OLIVIER, TOCCAFONDI, MIRCO, J. L. Lauer, G. B. Fields   +6 more
openaire   +3 more sources

Exogenously added GPI-anchored tissue inhibitor of matrix metal loproteinase-1 (TIMP-1) displays enhanced and novel biological activities [PDF]

, 2004
The family of tissue inhibitors of metalloproteinases (TIMPs) exhibits diverse physiological/biological functions including the inhibition of active matrix metalloproteinases, regulation of proMMP activation, cell growth, and the modulation of ...
P.J. Nelson, Belen Vicente, A., R. Djafarzadeh, Mojaat, A., Nelson, P. J., Djafarzadeh, R., Lüttichau, I. von, I. von Lüttichau, A. Belen Vicente, A. Mojaat   +9 more
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Histopathologic Findings Associated With Matrix Metalloproteinases Proceeding to Recurrence of Primary Spontaneous Pneumothorax in Adolescents

Frontiers in Pediatrics, 2021
Background: Primary spontaneous pneumothorax is potentially life-threatening, and its recurrence is always a serious problem. Pathological examination provides molecular insights into the pathophysiology of primary spontaneous pneumothorax.Objectives: To
Chih-Yung Chiu, Jim-Ray Chen, Shun-Ying Yin, Chia-Jung Wang, Tzu-Ping Chen, Tsan-Yu Hsieh   +5 more
doaj   +1 more source

Chemokine-induced secretion of gelatinase B in primary human monocytes [PDF]

, 2001
Chemokines help control normal leukocyte trafficking as well as their infiltration into tissues during acute and chronic inflammation. Matrix metalloproteinases (MMPs) help support the extravasation and infiltration of leukocytes through limited ...
Nelson, EL, Nelson, P. J., Schlöndorff, D, C.D. Cohen, D. Schlöndorff, C.M. Klier, Horuk, R, P.J. Nelson, Schlöndorff, D., Klier, C. M., E.L. Nelson, Nelson, PJ, Cohen, CD, Horuk, R., Cohen, C. D., R. Horuk, Klier, CM, Nelson, E. L.   +17 more
core   +1 more source