Results 21 to 30 of about 151,660 (260)

Prognostic value of determination of matrix metalloproteinase-1 and tissue inhibitor of matrix metalloproteinase-1 in follicular fluid in patients in vitro fertilization programs [PDF]

open access: yesГинекология, 2021
Aim. To determine the prognostic significance of matrix metalloproteinase-1 (MMP-1) and tissue metalloproteinase-1 inhibitor (TIMP-1) in the follicular fluid (FF) in patients with infertility to improve the effectiveness of in vitro fertilization (IVF ...
Olga A. Marinova   +2 more
doaj   +1 more source

Tissue Inhibitor of Metalloproteinase-1: Actions beyond Matrix Metalloproteinase Inhibition [PDF]

open access: yesCardiology, 2015
Matrix metalloproteinases (MMPs) are a family of zinc-dependent enzymes, which include 25 current members. MMPs degrade structural components of extracellular matrix and process bioactive molecules including cytokines, chemokines, and growth factors [1].
Merry L. Lindsey   +2 more
openaire   +2 more sources

Regulation of extracellular matrix In patients with Q-wave myocardial infarction after thrombolytic therapy

open access: yesPatologìâ, 2014
Aims. In order to study the levels of matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1, intracardiac hemodynamics, frequency of acute cardiac aneurysm development in patients with Q-wave myocardial infarction after thrombolysis, 74 ...
V. D. Syvolap , S. M. Kyselov
doaj   +1 more source

Effect of small interfering RNAs on matrix metalloproteinase 1 expression

open access: yesBiotechnology Reports, 2014
Three small double strand siRNAs (506-MMP1, 859-MMP1 and 891-MMP1), each contains 25–26 nucleotides, with high specific to human MMP1 were designed according to mRNA sequence of human MMP1 (NCBI, NM_002421). To monitor the MMP1 gene expression, the total
Gen-Hung Chen   +3 more
doaj   +1 more source

Expression of matrix metalloproteinase-1 and tissue inhibitor of metalloproteinase-1 in ulcerative colitis

open access: yesWorld Journal of Gastroenterology, 2006
To examine the expression of metalloproteinase-1 (MMP-1) and tissue inhibitor of metalloproteinase-1 (TIMP-1) in the colonic mucosa of patients with ulcerative colitis (UC).Reverse transcription-polymerase chain reaction (RT-PCR) and immunohistochemistry were used to study the expression of MMP-1 and TIMP-1 at both mRNA and protein levels in patients ...
Ying-De, Wang, Pei-Yun, Yan
openaire   +2 more sources

Levels of matrix metalloproteinase-1 and tissue inhibitors of metalloproteinase-1 in gastric cancer

open access: yesWorld Journal of Gastroenterology, 2011
To evaluate the levels of preoperative serum matrix metalloproteinase-1 (MMP-1) and tissue inhibitor of metalloproteinase-1 (TIMP-1) in gastric cancer.One hundred gastric cancer patients who underwent gastrectomy were enrolled in this study. The serum concentrations of MMP-1 and TIMP-1 in these patients and in fifty healthy controls were determined ...
Yılmaz, Özkan   +11 more
openaire   +4 more sources

Structural Basis for Matrix Metalloproteinase 1-Catalyzed Collagenolysis [PDF]

open access: yesJournal of the American Chemical Society, 2012
The proteolysis of collagen triple-helical structure (collagenolysis) is a poorly understood yet critical physiological process. Presently, matrix metalloproteinase 1 (MMP-1) and collagen triple-helical peptide models have been utilized to characterize the events and calculate the energetics of collagenolysis via NMR spectroscopic analysis of 12 enzyme-
BERTINI, IVANO   +6 more
openaire   +3 more sources

Diagnostic value of matrix metalloproteinase 9 and tissue inhibitor of matrix metalloproteinases 1 in cholesteatoma.

open access: yesHistology and histopathology, 2016
Matrix metalloproteinase 9 (MMP-9), able to degrade type IV collagen, plays a key role in inflammatory cell migration as well as in the destructive behaviour of cholesteatoma. The aim of our study was to compare the expression of MMP-9 and TIMP-1 in cholesteatoma tissue and in the concentrations in serum and plasma concentrations.Twenty five adult ...
Ewa, Olszewska   +7 more
openaire   +4 more sources

Matrix metalloproteinase-9, its inhibitor-1 and interleukines in experimental traumatic brain injury

open access: yesPatologìâ, 2016
Traumatic brain injury (TBI) is accompanied by high rates of morbidity and mortality in both developed and undeveloped countries that makes it one of the most actual medical and social problems. In recent years matrix metalloproteinases are in increasing
S. V. Ziablitsev, Ya. S. Yuzkiv
doaj   +1 more source

Assessment of Matrix Metalloproteinases a Prognostic Indicator in Advanced Fibrotic Lung Disease: A Systematic Review

open access: yesPakistan Journal of Medicine and Dentistry
Background: Fibrotic lung diseases were seen to have devastating effects among patients globally. Matrix metalloproteinases (MMP) including MMP-7, MMP-9, and MMP-1 have become promising biomarkers for idiopathic pulmonary fibrosis (IPF), and other ...
Mehvish Aqil   +6 more
doaj   +1 more source

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