Role of Matrix Metalloproteinase-2 in Eosinophil-Mediated Airway Remodeling
Airway remodeling is responsible for the progressive decline of lung function in bronchial asthma. Matrix metalloproteinase-2 and fibroblast-to-myofibroblast transition are involved in tissue remodeling.
Yu Kuwabara +10 more
doaj +1 more source
Purpose. To assess the role of selected matrix metalloproteinases in defective corneal re-epithelization in patients with recurrent corneal erosions. Subjects.
Katarzyna Jadczyk-Sorek +4 more
doaj +1 more source
Contribution of Matrix Metalloproteinase-9 to Cerebral Edema and Functional Outcome following Experimental Subarachnoid Hemorrhage [PDF]
Background: Cerebral edema is an important risk factor for death and poor outcome following subarachnoid hemorrhage (SAH). However, underlying mechanisms are still poorly understood.
Karsten Schöller +9 more
core +1 more source
Serum MMP-8 and TIMP-1 as prognostic biomarkers in gastric cancer
Despite gastric cancer being rare nowadays in Western countries, it remains one of the leading causes of cancer death worldwide. The course of the disease varies, so the individual gastric cancer patient’s prognosis is difficult to determine.
Alli Laitinen +7 more
doaj +1 more source
Cardiotrophin-1 induces matrix metalloproteinase-1 in human aortic endothelial cells. [PDF]
Rupture of an atherosclerotic plaque is a key event in the development of cardiovascular disorders, in which matrix metalloproteinase-1 (MMP-1) plays a crucial role by degradation of extracellular matrix resulting in plaque instability.
Akinori Tokito +3 more
doaj +1 more source
Identification of a novel 82 kDa proMMP-9 species associated with the surface of leukaemic cells [PDF]
MMP-9 (matrix metalloproteinase 9) plays a critical role in tumour progression. Although the biochemical properties of the secreted form of proMMP-9 are well characterized, little is known about the function and activity of cell surface-associated proMMP-
Mentele, Reinhard +6 more
core +1 more source
Background: Matrix metalloproteinase-1 (MMP-1) is a member of a family of enzymes that can degrade most extracellular matrix macromolecules. Extracellularly, MMPs are controlled by tissue inhibitors of metalloproteinases (TIMPs) and by mechanisms of pro ...
Pallavi S. Ghodpage +3 more
doaj +1 more source
Early joint erosions and serum levels of matrix metalloproteinase 1, matrix metalloproteinase 3, and tissue inhibitor of metalloproteinases 1 in rheumatoid arthritis [PDF]
To further evaluate the roles of matrix metalloproteinase 1 (MMP-1), MMP-3, and tissue inhibitor of metalloproteinases 1 (TIMP-1) in the pathogenesis of joint inflammation and articular erosions in early inflammatory arthritis.Untreated patients with joint symptoms for
Cunnane G +4 more
openaire +2 more sources
Human keratinocyte cell lines differ in the expression of the collagenolytic matrix metalloproteinases-1,-8, and-13 and of TIMP-1 [PDF]
Bachmeier BE, Nerlich AG, Boukamp P, et al. Human keratinocyte cell lines differ in the expression of the collagenolytic matrix metalloproteinases-1,-8, and-13 and of TIMP-1. BIOLOGICAL CHEMISTRY.
Boukamp, P +13 more
core +1 more source
Prognostic value of determination of matrix metalloproteinase-1 and tissue inhibitor of matrix metalloproteinase-1 in follicular fluid in patients in vitro fertilization programs [PDF]
Aim. To determine the prognostic significance of matrix metalloproteinase-1 (MMP-1) and tissue metalloproteinase-1 inhibitor (TIMP-1) in the follicular fluid (FF) in patients with infertility to improve the effectiveness of in vitro fertilization (IVF ...
Olga A. Marinova +2 more
doaj +1 more source

