Results 11 to 20 of about 151,660 (260)

Matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-1: a possible role in the pathogenesis of endometriosis [PDF]

Human Reproduction, 2002
Matrix metalloproteinases (MMPs) are a family of endopeptidases which play a role in the degradation and turnover of extracellular matrix proteins. Their action is regulated by specific tissue inhibitors called tissue inhibitors of metalloproteinases (TIMPs).We measured the concentrations of total and active MMP-9 in peritoneal fluid of infertile women
Jacek Szamatowicz, Laudański, Piotr, Tomaszewska, Izabela   +2 more
openaire   +2 more sources

Integrin α2β1 Expression Regulates Matrix Metalloproteinase-1-Dependent Bronchial Epithelial Repair in Pulmonary Tuberculosis

Frontiers in Immunology, 2018
Pulmonary tuberculosis (TB) is caused by inhalation of Mycobacterium tuberculosis, which damages the bronchial epithelial barrier to establish local infection.
Sara Brilha, Sara Brilha, Deborah L. W. Chong, Akif A. Khawaja, Catherine W. M. Ong, Catherine W. M. Ong, Naomi J. Guppy, Joanna C. Porter, Jon S. Friedland   +8 more
doaj   +1 more source

Increased Matrix Metalloproteinase-2 and Matrix Metalloproteinase-3 Concentrations in Corneal Epithelium of Patients with Recurrent Corneal Erosions

Journal of Ophthalmology, 2022
Purpose. To assess the role of selected matrix metalloproteinases in defective corneal re-epithelization in patients with recurrent corneal erosions. Subjects.
Katarzyna Jadczyk-Sorek, Wojciech Garczorz, Beata Bubała-Stachowicz, Tomasz Francuz, Ewa Mrukwa-Kominek   +4 more
doaj   +1 more source

Kallikrein‐1 Blockade Inhibits Aortic Expansion in a Mouse Model and Reduces Prostaglandin E2 Secretion From Human Aortic Aneurysm Explants

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Abdominal aortic aneurysm (AAA) is an important cause of mortality in older adults. The kinin B2 receptor agonist, bradykinin, has been implicated in AAA pathogenesis through promoting inflammation.
Corey S. Moran, Erik Biros, Smriti M. Krishna, Susan K. Morton, Daniel J. Sexton, Jonathan Golledge   +5 more
doaj   +1 more source

Role of Matrix Metalloproteinase-2 in Eosinophil-Mediated Airway Remodeling

Frontiers in Immunology, 2018
Airway remodeling is responsible for the progressive decline of lung function in bronchial asthma. Matrix metalloproteinase-2 and fibroblast-to-myofibroblast transition are involved in tissue remodeling.
Yu Kuwabara, Tetsu Kobayashi, Corina N. D'Alessandro-Gabazza, Masaaki Toda, Taro Yasuma, Kota Nishihama, Atsuro Takeshita, Hajime Fujimoto, Mizuho Nagao, Takao Fujisawa, Esteban C. Gabazza   +10 more
doaj   +1 more source

Matrix metalloproteinases in subjects with type 1 diabetes [PDF]

BMC Clinical Pathology, 2009
Abstract Background Nephropathy is serious complication of diabetes. We have previously shown that level of the proteoglycan syndecan-1 in blood is associated with ultrastructural kidney changes in young persons with type 1 diabetes.
Gharagozlian, Sedegheh, Svennevig, Katja, Bangstad, Hans-Jacob, Winberg, Jan-Olof, Olav Kolset, Svein   +4 more
openaire   +5 more sources

Serum MMP-8 and TIMP-1 as prognostic biomarkers in gastric cancer

Tumor Biology, 2018
Despite gastric cancer being rare nowadays in Western countries, it remains one of the leading causes of cancer death worldwide. The course of the disease varies, so the individual gastric cancer patient’s prognosis is difficult to determine.
Alli Laitinen, Jaana Hagström, Harri Mustonen, Arto Kokkola, Taina Tervahartiala, Timo Sorsa, Camilla Böckelman, Caj Haglund   +7 more
doaj   +1 more source

Cardiotrophin-1 induces matrix metalloproteinase-1 in human aortic endothelial cells. [PDF]

PLoS ONE, 2013
Rupture of an atherosclerotic plaque is a key event in the development of cardiovascular disorders, in which matrix metalloproteinase-1 (MMP-1) plays a crucial role by degradation of extracellular matrix resulting in plaque instability.
Akinori Tokito, Michihisa Jougasaki, Tomoko Ichiki, Shuichi Hamasaki   +3 more
doaj   +1 more source

Influence of phase I periodontal therapy on levels of matrix metalloproteinase 1 and tissue inhibitor of metalloproteinase 1

Saudi Dental Journal, 2014
Background: Matrix metalloproteinase-1 (MMP-1) is a member of a family of enzymes that can degrade most extracellular matrix macromolecules. Extracellularly, MMPs are controlled by tissue inhibitors of metalloproteinases (TIMPs) and by mechanisms of pro ...
Pallavi S. Ghodpage, Rajashri A. Kolte, Abhay P. Kolte, Madhur Gupta   +3 more
doaj   +1 more source

Early joint erosions and serum levels of matrix metalloproteinase 1, matrix metalloproteinase 3, and tissue inhibitor of metalloproteinases 1 in rheumatoid arthritis [PDF]

Arthritis & Rheumatism, 2001
To further evaluate the roles of matrix metalloproteinase 1 (MMP-1), MMP-3, and tissue inhibitor of metalloproteinases 1 (TIMP-1) in the pathogenesis of joint inflammation and articular erosions in early inflammatory arthritis.Untreated patients with joint symptoms for
Cunnane G, FitzGerald O, Beeton C, Cawston TE, Bresnihan B   +4 more
openaire   +2 more sources