Results 111 to 120 of about 188,223,062 (256)

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

The effects of sodium–glucose cotransporter 2 inhibitors on the ‘forgotten’ right ventricle

ESC Heart Failure, Volume 12, Issue 2, Page 1045-1058, April 2025.
Abstract With the progress in diagnosis, treatment and imaging techniques, there is a growing recognition that impaired right ventricular (RV) function profoundly affects the prognosis of patients with heart failure (HF), irrespective of their left ventricular ejection fraction (LVEF).
Liangzhen Qu, Xueting Duan, Han Chen
wiley   +1 more source

Missense glucokinase mutation in maturity-onset diabetes of the young and mutation screening in late-onset diabetes

, 1992
We describe a codon 299 mutation in the glucokinase gene in a British pedigree with maturity-onset diabetes of the young (MODY) resulting in a substitution of glycine to arginine.
Wainscote, J.S., Turner, R.C., J.S. Wainscoat, Lo, Y.M., P. Patel, Stoffel, M., Bell, J.I., Bell, G.I., A.M. Lucassen, G.I. Bell, R.C. Turner, Y-M.D. Lo, R. Page, Lucassen, A., M. Stoffel, Patel, P., A.T. Hattersley, J.I. Bell, Page, R., Hattersley, A.T.   +19 more
core   +1 more source

Characteristics of patients with diagnosis of maturity-onset diabetes of the young, according to the Russian diabetes registry

Сахарный диабет
BACKGROUND: Molecular genetic testing (MGT) is increasingly accessible, improving diagnosis of monogenic diabetes (DM), particularly maturity-onset diabetes of the young (MODY).
N. V. Rusyaeva, I. V. Kononenko, O. K. Vikulova, M. A. Isakov, M. V. Shestakova, N. G. Mokrysheva   +5 more
doaj   +1 more source

Considerations for drug trials in hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1095-1112, April 2025.
Abstract Hypertrophic cardiomyopathy (HCM) is a heterogeneous condition with potentially serious manifestations. Management has traditionally comprised therapies to palliate symptoms and implantable cardioverter‐defibrillators to prevent sudden cardiac death. The need for disease‐modifying therapies has been recognized for decades.
John P. Farrant, Matthias Schmitt, Anna B. Reid, Clifford J. Garratt, William G. Newman, Aneil Malhotra, Rhys Beynon, Masliza Mahmod, Betty Raman, Robert M. Cooper, Dana Dawson, Thomas Green, Sanjay K. Prasad, Anvesha Singh, Susanna Dodd, Hugh Watkins, Stefan Neubauer, Christopher A. Miller   +17 more
wiley   +1 more source

Outcomes of patients with post‐stroke epilepsy: A scoping review on quality of life, readmissions, costs, seizure recurrence, and medication adherence

Epilepsia Open, EarlyView.
Abstract Objective Post‐stroke epilepsy (PSE) affects ≈10% of patients with stroke and is associated with adverse health and economic outcomes. We aimed to review published literature on health and economic outcomes for patients with PSE, with a specific focus on quality of life, hospital readmissions, healthcare costs, seizure recurrence, and ...
Nega Dagnew Baye, Emma Foster, Muideen T. Olaiya, Nigel C. Jones, Monique F. Kilkenny, Lachlan L. Dalli   +5 more
wiley   +1 more source

Examining the clinical and genetic spectrum of maturity-onset diabetes of the young (MODY) in Iran

Scientific Reports
Maturity-onset diabetes of the young (MODY) is an uncommon monogenic type of diabetes mellitus. Detecting genetic variants for MODY is a necessity for precise diagnosis and treatment.
Sara Asgarian, Hossein Lanjanian, Shiva Rahimipour Anaraki, Farzad Hadaegh, Maryam Moazzam-Jazi, Leila Najd-Hassan-Bonab, Sajedeh Masjoudi, Asiyeh Sadat Zahedi, Maryam Zarkesh, Bita Shalbafan, Mahdi Akbarzadeh, Sahand Tehrani Fateh, Davood Khalili, Amirabbas Momenan, Narges Sarbazi, Mehdi Hedayati, Fereidoun Azizi, Maryam S. Daneshpour   +17 more
doaj   +1 more source

Health Services Utilization by Individuals With Eating Disorders in Norway: A Nationwide Register‐Linkage Study

European Eating Disorders Review, EarlyView.
ABSTRACT Objective This study investigated healthcare utilization by individuals with an eating disorder (ED) stratified by age and ED diagnosis. Method Data were retrieved from the Norwegian Patient Registry (NPR) and the Control and Payment of Health Reimbursements (KUHR).
Anne Martina Kraus, Deborah Lynn Reas, Hege Marie Gjefsen, Øyvind Rø, Katrine Damgaard Skyrud   +4 more
wiley   +1 more source

Maturity-onset diabetes of the young with necrobiosis lipoidica and granuloma annulare

, 2006
We describe a 12-year-old white girl with granuloma annulare localized to both ankles since she was five, necrobiosis lipoidica in the left pretibial region since she was ten, and a recent history of weakness, migraine, and weight loss.
VENTURA, ALESSANDRO, MARCHETTI F, Elena Faleschini, TONINI G., Giorgio Tonini, GERARDUZZI T, FALESCHINI E, Tania Gerarduzzi, LONGO F, Federico Marchetti, Longo, Filippo, Gerarduzzi, Tania, Faleschini, Elena, Filippo Longo, Alessandro Ventura, Tonini, Giorgio, Marchetti, Federico   +16 more
core   +1 more source

Correlates and Predictors of Binge Eating Disorder in Male Populations: A Systematic Review

European Eating Disorders Review, EarlyView.
ABSTRACT Objective This PRISMA‐compliant systematic review synthesises empirical literature on correlates and predictors of DSM‐5/DSM‐IV Binge Eating Disorder (BED) in male populations (PROSPERO: CRD420250644500). Method Eligible studies used male‐only samples, sex‐stratified analyses, or comparisons involving men with BED.
Sharon L. Grant, Kathleen De Boer
wiley   +1 more source