Results 121 to 130 of about 4,530 (193)

Chronic Nicotine Consumption and Withdrawal Regulate Melanocortin Receptor, CRF, and CRF Receptor mRNA Levels in the Rat Brain

Brain Sciences
Alterations in the various neuropeptide systems in the mesocorticolimbic circuitry have been implicated in negative effects associated with drug withdrawal.
Oguz Gozen, Buket Aypar, Meliha Ozturk Bintepe, Fulya Tuzcu, Burcu Balkan, Ersin O. Koylu, Lutfiye Kanit, Aysegul Keser   +7 more
doaj   +1 more source

Intraventricular Injection of LKB1 Inhibits the Formation of Diet-Induced Obesity in Rats by Activating the AMPK-POMC Neurons-Sympathetic Nervous System Axis

Cellular Physiology and Biochemistry, 2018
Background/Aims: Obesity is increasingly becoming a major public health problem worldwide. Peripheral LKB1 inhibits white fat generation, but the effect of central LKB1 on diet-induced obesity (DIO) is unknown.
Pengjiao Xi, Jianying Du, Huimin Liang, Jie Han, Zhaoxia Wu, Haomin Wang, Lu He, Qiming Wang, Haize Ge, Yongmei Li, Jie Xue, Derun Tian   +11 more
doaj   +1 more source

Coordinated changes in energy intake and expenditure following hypothalamic administration of neuropeptides involved in energy balance

, 2009
OBJECTIVE: The hypothalamic control of energy balance is regulated by a complex network of neuropeptide-releasing neurons. Whilst the effect of these neuropeptides on individual aspects of energy homeostasis has been studied, the coordinated response of ...
AC Linthorst, AD Howard, AJ Dunn, AM Wren, AP Goldstone, AS Chen, C Broberger, C Fekete, C Fekete, C J Small, CB Lawrence, CJ Billington, CK Song, CM Edwards, CR Abbott, CR Abbott, D Huszar, D J L Gunner, D Qu, EC Griffiths, GL de, GS Yeo, J Le Magnen, J Le Magnen, J R C Parkinson, JE Morley, JH Strubbe, JJ Hagan, JM Vaughan, JT Clark, K G Murphy, K Hashimoto, K L Smith, KG Mountjoy, KL Smith, L Negri, M A Ghatei, M Egawa, M Egawa, M Harris, M Monda, M Rossi, M Rossi, M Yokota, MM Ollmann, MM Wirth, MS Kim, MS Kim, N M Semjonous, NJ Spiteri, R Hanada, R Poggioli, S R Bloom, S Schuhler, T Hanada, T Sakurai, Y-L Liu   +56 more
core   +1 more source

Correlation study between genetic polymorphisms of melanocortin receptors and adrenocorticotropic hormone responsiveness in infantile spasms

Chinese Journal of Contemporary Neurology and Neurosurgery, 2012
Objective To explore the possible correlation between the genetic variations of the melanocortin receptors (MCRs, including MC2R, MC3R and MC4R) and adrenocorticotropic hormone (ACTH) responsiveness in patients with infantile spasms, and to investigate ...
Xiu⁃yu SHI, Ying⁃xue DING, Zhan⁃li LIU, Kai⁃li SHI, Li⁃ping ZOU   +4 more
doaj  

Obesity and Mutations in Mc4r and Mc3r

Acta Scientifci Nutritional Health, 2023
openaire   +1 more source

Biased agonism of G protein-coupled receptors as a novel strategy for osteoarthritis therapy

Bone Research
Osteoarthritis (OA) is a prevalent degenerative joint disorder marked by chronic pain, inflammation, and cartilage loss, with current treatments limited to symptom relief.
Xiangbo Meng, Ling Qin, Xinluan Wang
doaj   +1 more source

Melanocortin Peptides: Potential Targets in Systemic Lupus Erythematosus [PDF]

, 2014
Erin Corey Connolly-Strong, Lisa Carole Loram, Melissa Elizabeth Culp, Sheila Sturgill-Koszycki   +3 more
core   +1 more source

The accessory protein MRAP2 directly interacts with melanocortin-3 receptor to enhance signaling. [PDF]

Sci Signal
Jamaluddin A, Wyatt RA, Lee J, Dowsett GKC, Tadross JA, Broichhagen J, Yeo GSH, Levitz J, Gorvin CM.   +8 more
europepmc   +1 more source

The melanocortin receptors as targets for general obesity: contextualizing clinical failures and analyzing future perspectives. [PDF]

Front Endocrinol (Lausanne)
Prindle CR, Bennett TL, Rajewski BH, Kelley KJ, Impastato AC, Potterfield R, Marks DL, Delev JY.   +7 more
europepmc   +1 more source

Glucose Intake during the Neonatal Period Modulates the Central Melanocortin System with Breed-Specific Differences. [PDF]

J Poult Sci
Kimura K, Watanabe Y, Ashizawa S, Matsushita K, Nakao N, Ohta Y, Shiraishi JI.   +6 more
europepmc   +1 more source